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McDougald WA, Miyaoka RS, Alessio AM, et al. A study of SPECT/CT camera stability for quantitative imaging. EJNMMI Phys. 2016;3(1):14doi: 10.1186/s40658-016-0150-7.
McDougald, W. A., Miyaoka, R. S., Alessio, A. M., Harrison, R. L., & Lewellen, T. K. (2016). A study of SPECT/CT camera stability for quantitative imaging. EJNMMI physics, 3(1), 14. https://doi.org/10.1186/s40658-016-0150-7
McDougald, Wendy A, et al. "A study of SPECT/CT camera stability for quantitative imaging." EJNMMI physics vol. 3,1 (2016): 14. doi: https://doi.org/10.1186/s40658-016-0150-7
McDougald WA, Miyaoka RS, Alessio AM, Harrison RL, Lewellen TK. A study of SPECT/CT camera stability for quantitative imaging. EJNMMI Phys. 2016 Dec;3(1):14. doi: 10.1186/s40658-016-0150-7. Epub 2016 Jul 29. PMID: 27473290; PMCID: PMC4967048.
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EJNMMI Phys. 2016 Dec;3(1):14. doi: 10.1186/s40658-016-0150-7. Epub 2016 Jul 29.

A study of SPECT/CT camera stability for quantitative imaging.

EJNMMI physics

Wendy A McDougald, Robert S Miyaoka, Adam M Alessio, Robert L Harrison, Thomas K Lewellen

Affiliations

  1. Imaging Research Laboratory, Department of Radiology, University of Washington, 222 Portage Bay Building, Box 357987, Seattle, WA, 98195-7987, USA. [email protected].
  2. Imaging Research Laboratory, Department of Radiology, University of Washington, 222 Portage Bay Building, Box 357987, Seattle, WA, 98195-7987, USA.

PMID: 27473290 PMCID: PMC4967048 DOI: 10.1186/s40658-016-0150-7

Abstract

BACKGROUND: The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for quantitative SPECT. Using a cylindrical water phantom filled with measured amounts of (99m)Tc, factors were calculated to convert counts/cc to activity/cps. Measurements were made over an 18-month period. System sensitivity data calculated from (57)Co daily quality assurance (DQA) flood acquisitions were then compared to the (99m)Tc calibration factors to determine the relationship of the factors.

RESULTS: The coefficient of variation is 2.7 % for the (99m)Tc cylinder conversion factors and 2.6 % for the (57)Co DQA flood data. The greatest difference between the cylinder conversion factors and the flood data is less than 3 %.

CONCLUSIONS: Based on the results, the camera was stable within 3 % over an 18-month time period. The daily flood source acquisitions can be a reliable source for tracking camera stability and may provide information on updating the calibration factor for quantitative imaging.

Keywords: Conversion factor; SUV accuracy; Single photon emission tomography with computer tomography (SPECT/CT) quantitation

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