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Turk Pediatri Ars. 2016 Sep 01;51(3):166-168. doi: 10.5152/TurkPediatriArs.2016.2001. eCollection 2016 Sep.

Sjögren's syndrome associated with systemic lupus erythematosus.

Turk pediatri arsivi

Mehmet Taşdemir, Chiar Hasan, Ayşe Ağbaş, Özgür Kasapçopur, Nur Canpolat, Lale Sever, Salim Çalışkan

Affiliations

  1. Department of Pediatrics, Division of Pediatric Nephrology, ?stanbul University Cerrahpa?a School of Medicine, ?stanbul, Turkey.
  2. Department of Pediatrics, ?stanbul University Cerrahpa?a School of Medicine, ?stanbul, Turkey.
  3. Department of Pediatrics, Division of Pediatric Rheumatology, ?stanbul University Cerrahpa?a School of Medicine, ?stanbul, Turkey.

PMID: 27738403 PMCID: PMC5047367 DOI: 10.5152/TurkPediatriArs.2016.2001

Abstract

Systemic lupus erythematosus and Sjögren's syndrome are chronic auto- inflammatory disorders which can lead to serious organ damage. Although systemic lupus erythematosus and Sjögren's syndrome were previously considered two forms of the same disease because of presence of clinical coexistence of these two conditions, the view that they are two different conditions with mutual characteristics has become prominent in recent years. In this paper, we reported a 16 year-old girl who was followed up with a diagnosis of Sjögren's syndrome for six years and then was observed to have overlap of systemic lupus erythematosus. In the baseline, she did not have any clinical or serological evidence for systemic lupus erythematosus. After six year, massive proteinuria and serological findings developed and systemic lupus erythematosus nephritis was diagnosed by kidney biopsy. Currently, systemic lupus erythematosus and Sjögren's syndrome cannot be differentiated definetely. We need more valuable diagnostic and classification criteria to differentiate these two important conditions.

Keywords: Childhood; Sjögren’s syndrome; systemic lupus erythematosus

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