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Nalçacıoğlu P, Çakar Özdal P, Şimşek M. Clinical Characteristics of Fuchs' Uveitis Syndrome. Turk J Ophthalmol. 2016;46(2):52-57doi: 10.4274/tjo.99897.
Nalçacıoğlu, P., Çakar Özdal, P., & Şimşek, M. (2016). Clinical Characteristics of Fuchs' Uveitis Syndrome. Turkish journal of ophthalmology, 46(2), 52-57. https://doi.org/10.4274/tjo.99897
Nalçacıoğlu, Pınar, et al. "Clinical Characteristics of Fuchs' Uveitis Syndrome." Turkish journal of ophthalmology vol. 46,2 (2016): 52-57. doi: https://doi.org/10.4274/tjo.99897
Nalçacıoğlu P, Çakar Özdal P, Şimşek M. Clinical Characteristics of Fuchs' Uveitis Syndrome. Turk J Ophthalmol. 2016 Apr;46(2):52-57. doi: 10.4274/tjo.99897. Epub 2016 Apr 05. PMID: 27800260; PMCID: PMC5082249.
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Turk J Ophthalmol. 2016 Apr;46(2):52-57. doi: 10.4274/tjo.99897. Epub 2016 Apr 05.

Clinical Characteristics of Fuchs' Uveitis Syndrome.

Turkish journal of ophthalmology

Pınar Nalçacıoğlu, Pınar Çakar Özdal, Mert Şimşek

Affiliations

  1. Y?ld?r?m Beyaz?t University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey.
  2. Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

PMID: 27800260 PMCID: PMC5082249 DOI: 10.4274/tjo.99897

Abstract

OBJECTIVES: To evaluate the clinical and demographic properties of Fuchs' uveitis syndrome (FUS) in Turkish patients.

MATERIALS AND METHODS: The medical records of 161 patients with FUS followed in the Uveitis Division of Ulucanlar Eye Hospital between 1996 and 2014 were respectively reviewed. The mean age at diagnosis, sex, the number of affected eyes, follow-up period, clinical findings at presentation, complications during the follow-up period, medical and surgical treatments, and best corrected visual acuity at the initial and final visits were recorded.

RESULTS: The study included 171 eyes of 161 patients diagnosed with FUS. Of the patients, 94 (58.4%) were female and 67 (41.6%) were male. The mean age at presentation was 35.2±11.0 (11-65) years. The mean follow-up period was 23.5±32.8 (2-216) months. Ten (6.2%) patients had bilateral involvement. The most common symptoms at presentation were decreased visual acuity or blurred vision in 63 (39.1%) and floaters in 19 (11.8%) patients. Clinical findings at presentation included diffuse small, round, white keratic precipitates in 128 (74.8%) eyes, anterior chamber reaction in 82 (47.9%), vitreous cells in 122 (71.3%), heterochromia in 47 (27.4%) and iris nodules in 32 (18.7%) eyes. During the follow-up period, elevated intraocular pressure occured in 31 (18.1%) eyes and the most common complication was cataract development (89 eyes, 52.0%).

CONCLUSION: Heterochromia was observed in 27.4% of patients in our study. However, the diffuse small, round keratic precipitates, low-grade anterior chamber reaction and varying degrees of vitreous reaction are more common clinical characteristics that are helpful in making the diagnosis.

Keywords: Cataract; Fuchs’ uveitis syndrome; complications; heterochromia; intraocular pressure

Conflict of interest statement

No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study received no financial support.

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