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Opendak M, Sullivan RM. Unique neurobiology during the sensitive period for attachment produces distinctive infant trauma processing. Eur J Psychotraumatol. 2016;7:31276doi: 10.3402/ejpt.v7.31276.
Opendak, M., & Sullivan, R. M. (2016). Unique neurobiology during the sensitive period for attachment produces distinctive infant trauma processing. European journal of psychotraumatology, 731276. https://doi.org/10.3402/ejpt.v7.31276
Opendak, Maya, and Sullivan, Regina M. "Unique neurobiology during the sensitive period for attachment produces distinctive infant trauma processing." European journal of psychotraumatology vol. 7 (2016): 31276. doi: https://doi.org/10.3402/ejpt.v7.31276
Opendak M, Sullivan RM. Unique neurobiology during the sensitive period for attachment produces distinctive infant trauma processing. Eur J Psychotraumatol. 2016 Nov 08;7:31276. doi: 10.3402/ejpt.v7.31276. eCollection 2016. PMID: 27837581; PMCID: PMC5106868.
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Eur J Psychotraumatol. 2016 Nov 08;7:31276. doi: 10.3402/ejpt.v7.31276. eCollection 2016.

Unique neurobiology during the sensitive period for attachment produces distinctive infant trauma processing.

European journal of psychotraumatology

Maya Opendak, Regina M Sullivan

Affiliations

  1. Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
  2. Child Study Center, Child & Adolescent Psychiatry, New York University School of Medicine, New York, NY, USA; [email protected].
  3. Child Study Center, Child & Adolescent Psychiatry, New York University School of Medicine, New York, NY, USA.

PMID: 27837581 PMCID: PMC5106868 DOI: 10.3402/ejpt.v7.31276

Abstract

BACKGROUND: Trauma has neurobehavioral effects when experienced at any stage of development, but trauma experienced in early life has unique neurobehavioral outcomes related to later life psychiatric sequelae. Recent evidence has further highlighted the context of infant trauma as a critical variable in determining its immediate and enduring consequences. Trauma experienced from an attachment figure, such as occurs in cases of caregiver child maltreatment, is particularly detrimental.

METHODS: Using data primarily from rodent models, we review the literature on the interaction between trauma and attachment in early life, which highlights the role of the caregiver's presence in engagement of attachment brain circuitry and suppressing threat processing by the amygdala. We then consider how trauma with and without the caregiver produces long-term changes in emotionality and behavior, and suggest that these experiences initiate distinct pathways to pathology.

RESULTS: Together these data suggest that infant trauma processing and its enduring effects are impacted by both the immaturity of brain areas for processing trauma and the unique functioning of the early-life brain, which is biased toward processing information within the attachment circuitry.

CONCLUSION: An understanding of developmental differences in trauma processing as well as the critical role of the caregiver in further altering early life brain processing of trauma is important for developing age-relevant treatment and interventions.

Keywords: Trauma; amygdala; attachment; development; infant; maternal care; sensitive period; stress

Conflict of interest statement

and funding There is no conflict of interest in the present study for any of the authors.

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