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Rodríguez CH, Nastro M, Calvo JL, et al. In vitro activity of colistin against Stenotrophomonas maltophilia. J Glob Antimicrob Resist. 2014;2(4):316-317doi: 10.1016/j.jgar.2014.04.004.
Rodríguez, C. H., Nastro, M., Calvo, J. L., Fariña, M. E., Dabos, L., & Famiglietti, A. (2014). In vitro activity of colistin against Stenotrophomonas maltophilia. Journal of global antimicrobial resistance, 2(4), 316-317. https://doi.org/10.1016/j.jgar.2014.04.004
Rodríguez, Carlos Hernan, et al. "In vitro activity of colistin against Stenotrophomonas maltophilia." Journal of global antimicrobial resistance vol. 2,4 (2014): 316-317. doi: https://doi.org/10.1016/j.jgar.2014.04.004
Rodríguez CH, Nastro M, Calvo JL, Fariña ME, Dabos L, Famiglietti A. In vitro activity of colistin against Stenotrophomonas maltophilia. J Glob Antimicrob Resist. 2014 Dec;2(4):316-317. doi: 10.1016/j.jgar.2014.04.004. Epub 2014 Jun 05. PMID: 27873694.
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J Glob Antimicrob Resist. 2014 Dec;2(4):316-317. doi: 10.1016/j.jgar.2014.04.004. Epub 2014 Jun 05.

In vitro activity of colistin against Stenotrophomonas maltophilia.

Journal of global antimicrobial resistance

Carlos Hernan Rodríguez, Marcela Nastro, Jimena Lopez Calvo, Maria Elisa Fariña, Laura Dabos, Angela Famiglietti

Affiliations

  1. Laboratorio de Bacteriología, Departamento de Bioquímica Clínica, Hospital de Clínicas José de San Martín, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina. Electronic address: [email protected].
  2. Laboratorio de Bacteriología, Departamento de Bioquímica Clínica, Hospital de Clínicas José de San Martín, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  3. Servicio de Farmacia, Hospital de Clínicas José de San Martín, Universidad de Buenos Aires, Buenos Aires, Argentina.

PMID: 27873694 DOI: 10.1016/j.jgar.2014.04.004

Abstract

Colistin is one of the few antimicrobials that retains activity against multidrug-resistant Gram-negative bacteria. However, the emergence of colistin resistance has been described recently. The aims of this study were to determine the activity of colistin against isolates of Stenotrophomonas maltophilia. In total, 641 S. maltophilia clinical isolates were obtained from single patients admitted to a university hospital in Buenos Aires city, Argentina, between the years 1996 and 2013. Susceptibility to colistin was determined by the agar dilution method. An increase in colistin resistance from 8% in 1996 to 45% in 2013 was observed, which correlated with a marked increase in colistin consumption of 11.4-fold during the same period.

Copyright © 2014 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

Keywords: Colistin resistance; Colistin usage; Stenotrophomonas maltophilia

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