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Iran J Psychiatry Behav Sci. 2016 Aug 15;10(3):e681. doi: 10.17795/ijpbs-681. eCollection 2016 Sep.

Combined Administration of .

Iranian journal of psychiatry and behavioral sciences

Mohaddese Mahboubi, Mohsen Taghizadeh, Sayyed Alireza Talaei, Sayyed Mehdi Takht Firozeh, Ali Akbar Rashidi, Omid Reza Tamtaji

Affiliations

  1. Microbiology Department, Medicinal Plant Research Center of Barij Essence, Kashan, IR Iran.
  2. Research Center for Biochemistry and Nutrition in Metabolic disorders, Kashan University of Medical Sciences, Kashan, IR Iran.
  3. Physiology Research Center, Kashan University of Medical Sciences, Kashan, IR Iran.

PMID: 27822272 PMCID: PMC5097832 DOI: 10.17795/ijpbs-681

Abstract

OBJECTIVES: In this study, we evaluated the protective effects of combined form of these extracts on memory improvement of scopolamine treated rats by the Morris water maze method.

MATERIALS AND METHODS: Two groups (group 1 and 2) of animals were pretreated with combined extracts of

RESULTS: For time spent and distance, there was no substantial difference between groups 1, 2 and 4, while they had statistical difference with group 3 (P = 0.001). The spatial memory evaluation showed no significant difference between treated groups and normal group.

CONCLUSIONS: Therefore, the combination of the two extracts had the ability to improve memory as its traditional use.

Keywords: Boswellia serrata; Melissa officinalis; Rat; Scopolamine; Spatial Memory

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