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Front Physiol. 2020 Aug 21;11:1049. doi: 10.3389/fphys.2020.01049. eCollection 2020.

Baroreflex Modulation During Acute High-Altitude Exposure in Rats.

Frontiers in physiology

Ana Rosa Beltrán, Alexis Arce-Álvarez, Rodrigo Ramirez-Campillo, Manuel Vásquez-Muñoz, Magdalena von Igel, Marco A Ramírez, Rodrigo Del Rio, David C Andrade

Affiliations

  1. Departamento de Educación, Facultad de Educación, Universidad de Antofagasta, Antofagasta, Chile.
  2. Laboratorio de Fisiología Celular, Departamento Biomédico, Facultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.
  3. Escuela de Kinesiología, Facultad de Salud, Universidad Católica Silva Henríquez, Santiago, Chile.
  4. Laboratory of Human Performance, Quality of Life and Wellness Research Group, Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile.
  5. Centro de Investigación en Fisiología del Ejercicio, Facultad de Ciencias, Universidad Mayor, Santiago, Chile.
  6. Laboratory of Cardiorespiratory Control, Department of Physiology, Pontificia Universidad Católica de Chile, Santiago, Chile.
  7. Centro de Envejecimiento y Regeneración (CARE), Pontificia Universidad Católica de Chile, Santiago, Chile.
  8. Centro de Excelencia en Biomedicina de Magallanes (CEBIMA), Universidad de Magallanes, Punta Arenas, Chile.
  9. Pedagogía en Educación Física, Deportes y Recreación, Universidad Mayor, Santiago, Chile.

PMID: 32973562 PMCID: PMC7472463 DOI: 10.3389/fphys.2020.01049

Abstract

Baroreflex (BR) control is critically dependent of sympathetic and parasympathetic modulation. It has been documented that during acute hypobaric hypoxia there is a BR control impairment, however, the effect of a natural hypoxic environment on BR function is limited and controversial. Therefore, the aim of this study was to determine the effect of acute High-Altitude exposure on sympathetic/parasympathetic modulation of BR control in normal rats. Male Sprague Dawley rats were randomly allocated into Sea-Level (

Copyright © 2020 Beltrán, Arce-Álvarez, Ramirez-Campillo, Vásquez-Muñoz, von Igel, Ramírez, Del Rio and Andrade.

Keywords: autonomic nervous system; baroreceptors; baroreflex; parasympathetic nervous system; sympathetic nervous system

References

  1. Hypertension. 2016 Aug;68(2):436-45 - PubMed
  2. Am J Physiol Regul Integr Comp Physiol. 2002 Oct;283(4):R815-26 - PubMed
  3. J Physiol. 1972 Jun;223(2):525-48 - PubMed
  4. Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2364-72 - PubMed
  5. Aviat Space Environ Med. 2006 Sep;77(9):915-20 - PubMed
  6. PLoS One. 2014 May 01;9(5):e94927 - PubMed
  7. Front Physiol. 2014 Nov 12;5:434 - PubMed
  8. Eur J Appl Physiol Occup Physiol. 1994;69(6):502-7 - PubMed
  9. Circ Res. 1975 Apr;36(4):536-46 - PubMed
  10. J Am Coll Cardiol. 2013 Dec 24;62(25):2422-2430 - PubMed
  11. Bull Exp Biol Med. 2000 Apr;129(4):327-9 - PubMed
  12. Wilderness Environ Med. 2019 Sep;30(3):260-267 - PubMed
  13. J Appl Physiol (1985). 2017 Sep 1;123(3):567-577 - PubMed
  14. Am J Physiol Regul Integr Comp Physiol. 2007 Jul;293(1):R3-R12 - PubMed
  15. Eur J Appl Physiol. 2017 Dec;117(12):2401-2407 - PubMed
  16. J Physiol. 2017 Mar 1;595(5):1619-1626 - PubMed
  17. Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H2269-76 - PubMed
  18. Sheng Li Xue Bao. 2004 Jun 25;56(3):269-81 - PubMed
  19. PLoS One. 2014 Jan 03;9(1):e84274 - PubMed
  20. Clin Sci (Lond). 2019 Feb 5;133(3):393-405 - PubMed
  21. J Appl Physiol (1985). 2004 Sep;97(3):935-40 - PubMed
  22. J Physiol. 2003 Oct 1;552(Pt 1):295-302 - PubMed
  23. PLoS One. 2018 Jan 12;13(1):e0190830 - PubMed
  24. J Physiol. 2010 Apr 1;588(Pt 7):1129-38 - PubMed
  25. Hypertension. 2007 Jul;50(1):6-13 - PubMed
  26. Am J Physiol. 1993 Aug;265(2 Pt 2):R365-70 - PubMed
  27. J Physiol. 2019 May;597(9):2379-2390 - PubMed
  28. Am J Physiol Regul Integr Comp Physiol. 2002 Aug;283(2):R284-6 - PubMed
  29. J Vis Exp. 2015 Jan 30;(95): - PubMed
  30. J Clin Invest. 1991 Jun;87(6):1953-7 - PubMed
  31. Clin Auton Res. 2007 Feb;17(1):13-9 - PubMed
  32. Am J Physiol. 1999 Feb;276(2):R500-4 - PubMed
  33. Acta Physiol Scand. 1998 Mar;162(3):389-99 - PubMed
  34. Adv Exp Med Biol. 1996;410:439-42 - PubMed
  35. Am J Physiol. 1997 Oct;273(4):R1219-23 - PubMed
  36. Am J Cardiol. 1992 Feb 15;69(5):523-31 - PubMed

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