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Eur Heart J Case Rep. 2020 Jun 24;4(4):1-5. doi: 10.1093/ehjcr/ytaa122. eCollection 2020 Aug.

A case report of isolated right ventricular lymphocytic myocarditis.

European heart journal. Case reports

Praveen Indraratna, Vanathi Sivasubramaniam, Trent Davidson, Simon Eggleton

Affiliations

  1. Department of Cardiology, Level 3 Campus Centre, Prince of Wales Hospital, Barker St., Sydney, NSW 2031, Australia.
  2. Faculty of Medicine, The University of New South Wales, High St., Kensington, Sydney 2052, Australia.
  3. Department of Anatomical Pathology, St. Vincent's Hospital, Victoria St., Darlinghurst, Sydney 2010, Australia.
  4. New South Wales Health Pathology East, Prince of Wales Hospital, Barker St., Randwick, Sydney, NSW 2031, Australia.

PMID: 32974433 PMCID: PMC7501889 DOI: 10.1093/ehjcr/ytaa122

Abstract

BACKGROUND: Lymphocytic myocarditis is an uncommon condition with a variety of clinical presentations. Isolated involvement of the right ventricle (RV) is very rare. We present a case of a young woman who developed right ventricular dysfunction and arrhythmias as a consequence of this condition, which appeared to be chronic at diagnosis.

CASE SUMMARY: A 26-year-old lady was admitted to hospital following routine echocardiography, requested for screening of pulmonary hypertension in the context of known hypersensitivity pneumonitis. This echocardiogram demonstrated severe right ventricular dilatation and impairment. She was also experiencing atrial fibrillation and non-sustained, symptomatic episodes of ventricular tachycardia. Endomyocardial biopsy revealed lymphocytic myocarditis. She was managed with azathioprine and prednisone, as well as sotalol and apixaban for her atrial fibrillation, and has had no complications in the 12 months since discharge.

DISCUSSION: Lymphocytic myocarditis isolated to the RV has only been reported in two previous cases, both of which were acute, dramatic presentations. This is the first report of a chronic example of this disease process. Due to her intercurrent immunosuppression, this patient may have been pre-disposed to the condition either by re-activation of a latent viral infection or partial treatment of a true autoimmune lymphocytic myocarditis.

© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.

Keywords: Atrial fibrillation; Cardiomyopathy; Case report; Lymphocytic myocarditis; Right ventricle

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