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Westmark CJ, Chuang SC, Hays SA, et al. APP Causes Hyperexcitability in Fragile X Mice. Front Mol Neurosci. 2016;9:147doi: 10.3389/fnmol.2016.00147.
Westmark, C. J., Chuang, S. C., Hays, S. A., Filon, M. J., Ray, B. C., Westmark, P. R., Gibson, J. R., Huber, K. M., & Wong, R. K. (2016). APP Causes Hyperexcitability in Fragile X Mice. Frontiers in molecular neuroscience, 9147. https://doi.org/10.3389/fnmol.2016.00147
Westmark, Cara J, et al. "APP Causes Hyperexcitability in Fragile X Mice." Frontiers in molecular neuroscience vol. 9 (2016): 147. doi: https://doi.org/10.3389/fnmol.2016.00147
Westmark CJ, Chuang SC, Hays SA, Filon MJ, Ray BC, Westmark PR, Gibson JR, Huber KM, Wong RK. APP Causes Hyperexcitability in Fragile X Mice. Front Mol Neurosci. 2016 Dec 15;9:147. doi: 10.3389/fnmol.2016.00147. eCollection 2016. PMID: 28018172; PMCID: PMC5156834.
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Front Mol Neurosci. 2016 Dec 15;9:147. doi: 10.3389/fnmol.2016.00147. eCollection 2016.

APP Causes Hyperexcitability in Fragile X Mice.

Frontiers in molecular neuroscience

Cara J Westmark, Shih-Chieh Chuang, Seth A Hays, Mikolaj J Filon, Brian C Ray, Pamela R Westmark, Jay R Gibson, Kimberly M Huber, Robert K S Wong

Affiliations

  1. Department of Neurology, University of Wisconsin-Madison, Madison Madison, WI, USA.
  2. Department of Physiology and Pharmacology, State University of New York Downstate Medical Center Brooklyn, NY, USA.
  3. Department of Neuroscience, University of Texas Southwestern Medical Center Dallas, TX, USA.
  4. Department of Medicine, University of Wisconsin-Madison, Madison Madison, WI, USA.

PMID: 28018172 PMCID: PMC5156834 DOI: 10.3389/fnmol.2016.00147

Abstract

Amyloid-beta protein precursor (APP) and metabolite levels are altered in fragile X syndrome (FXS) patients and in the mouse model of the disorder,

Keywords: amyloid-beta; amyloid-beta precursor protein; fragile X mental retardation protein; fragile X syndrome; hyperexcitability

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