H Bayrak, A Demirbas, N Demirbas… - European journal of …, 2009 - Elsevier

Synthesis of some new 1, 2, 4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities.

evaluation

Bayrak, Demirbas, Demirbas

GSID: JDTlwllibDMJ

Excerpt

5-Pyridin-4-yl-1,3,4-oxadiazole-2-thiol (2) was obtained from the reaction of isonicotinic acid hydrazide with carbon disulfide in basic media and converted into 4-amino-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (5) by the treatment with hydrazine hydrate. The synthesis of 3 and 6 …

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