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A Hurria, L Jones, HB Muss - American Society of Clinical Oncology …, 2016 - ascopubs.org

Cancer treatment as an accelerated aging process: assessment, biomarkers, and interventions.

Stem career interventions

Jones

GSID: RMdhnGPqIl4J

Excerpt

KEY POINTS Cancer and/or its treatment may contribute to an accelerated aging phenotype. A key survivorship issue facing older adults is the short-and long-term impact of cancer therapy on the aging process. Clinical (geriatric assessment) and biologic markers of aging hold great promise as independent predictors of patient outcomes including toxicity, functional reserve, and survival. Standard cancer treatment causes significant and marked impairments in global cardiovascular function, which may persist years after the cessation of …

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GSID: _-Bj3qkfkjsJ