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SM Castellino, NJ Ullrich, MJ Whelen… - Journal of the National …, 2014 - academic.oup.com

Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.

Stem career interventions

[No authors listed]

GSID: nMIDJegM7k4J

Excerpt

Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction, commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic leukemia (ALL), or tumors involving the head and neck. Risk factors for cancer-related cognitive dysfunction include young age at diagnosis, treatment with cranial irradiation, use of parenteral or intrathecal methotrexate, female sex, and pre-existing comorbidities. Limiting use and reducing doses and volume of cranial irradiation while intensifying …

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