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Mennenga, S. E., Gerson, J. E., Dunckley, T., & Bimonte-Nelson, H. A. (2015). Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing. Physiology & behavior, 138, 260-265.
Mennenga, Sarah E., et al. "Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing." Physiology & behavior 138 (2015): 260-265.
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SE Mennenga, JE Gerson, T Dunckley… - Physiology & …, 2015 - Elsevier

Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing.

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Mennenga

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Harmine is a naturally occurring monoamine oxidase inhibitor that has recently been shown to selectively inhibit the dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (DYRK1A). We investigated the cognitive effects of 1 mg (low) Harmine and 5 mg (high) Harmine using the delayed-match-to-sample (DMS) asymmetrical 3-choice water maze task to evaluate spatial working and recent memory, and the Morris water maze task (MM) to test spatial reference memory. Animals were also tested on the visible platform task, a water …

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