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SUBRAMANIAM, Krishanthi S., et al. Anti-α-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by Leishmania major. Parasitology, 2018, vol. 145, no 13, p. 1758-1764.
Subramaniam, K. S., Austin, V., Schocker, N. S., Montoya, A. L., Anderson, M. S., Ashmus, R. A., ... & Acosta-Serrano, A. (2018). Anti-α-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by Leishmania major. Parasitology, 145(13), 1758-1764.
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KS Subramaniam, V Austin, NS Schocker, AL Montoya… - Parasitology, 2018 - cambridge.org

Anti-α-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by Leishmania major.

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Montoya, Schocker, Subramaniam

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Excerpt

Outbreaks of Old World cutaneous leishmaniasis (CL) have significantly increased due to the conflicts in the Middle East, with most of the cases occurring in resource-limited areas such as refugee settlements. The standard methods of diagnosis include microscopy and parasite culture, which have several limitations. To address the growing need for a CL diagnostic that can be field applicable, we have identified five candidate neoglycoproteins (NGPs): Galα (NGP3B), Galα (1, 3) Galα (NGP17B), Galα (1, 3) Galβ (NGP9B), Galα (1 …

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