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Y Liu, H Meng, S Konst, R Sarmiento… - … applied materials & …, 2014 - ACS Publications

Injectable dopamine-modified poly (ethylene glycol) nanocomposite hydrogel with enhanced adhesive property and bioactivity.

Louis Stokes Alliances for Minority Participation AND Program Evaluation

Liu, Meng, Sarmiento

GSID: tDT4wXp2TaoJ

Excerpt

A synthetic mimic of mussel adhesive protein, dopamine-modified four-armed poly (ethylene glycol)(PEG-D4), was combined with a synthetic nanosilicate, Laponite (Na0. 7+(Mg5. 5Li0. 3Si8) O20 (OH) 4) 0.7–), to form an injectable naoncomposite tissue adhesive hydrogel. Incorporation of up to 2 wt% Laponite significantly reduced the cure time while enhancing the bulk mechanical and adhesive properties of the adhesive due to strong interfacial binding between dopamine and Laponite. The addition of Laponite did not alter the …

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