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Lynch, B., Crawford, K., Baruti, O., Abdulahad, A., Webster, M., Puetzer, J., ... & Mendenhall, J. (2017). The effect of hypoxia on thermosensitive poly (N‐vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105(7), 1863-1873.
Lynch, Brandon, et al. "The effect of hypoxia on thermosensitive poly (N‐vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering." Journal of Biomedical Materials Research Part B: Applied Biomaterials 105.7 (2017): 1863-1873.
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B Lynch, K Crawford, O Baruti… - … Research Part B …, 2017 - Wiley Online Library

The effect of hypoxia on thermosensitive poly(N‐vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering.

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Excerpt

Cartilage repair presents a daunting challenge in tissue engineering applications due to the low oxygen conditions (hypoxia) affiliated in diseased states. Hence, the use of biomaterial scaffolds with unique variability is imperative to treat diseased or damaged cartilage. Thermosensitive hydrogels show promise as injectable materials that can be used as tissue scaffolds for cartilage tissue regeneration. However, uses in clinical applications are limited to due mechanical stability and therapeutic efficacy to treat diseased tissue. In this study …

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