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V Arora, A Kuhad, K Chopra - The Journal of Pain, 2012 - jpain.org

Diversification of biogenic amines, substance P and neurotrophic factor produces chronic muscular pain and tactile allodynia accompanied by depression--A putative ….

STEM and diversification

Arora

GSID: X6YFPAbT4RIJ

Excerpt

Numerous studies point to the frequent co-morbidity between pain and depression. In clinical practice, depression is often associated with an increased incidence of clinical pain complaints and thus, the co-morbidity of pain and depression has been suggested to be a common phenomenon. This complex interaction is often labeled as Depression-Pain syndrome or Pain-Depression dyad, implying that the condition often coexist and respond to similar treatments, exacerbate one another, and share biological pathways. The biochemical …

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