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M Gomes, A Ghosh, K Roelofs… - Journal of …, 2010 - journalofsurgicalresearch.com

Increased Serine Protease Activation Is Associated with AAA Formation in Males, But Not in Females, in The Elastase Induced Rodent Aneurysm Model.

STEM and males

[No authors listed]

GSID: EmtjCFmTH_gJ

Excerpt

Purpose: Paralysis from spinal cord blood supply interruption after endovascular thoracic aortic repair remains a significant risk. The purpose of this study was to develop an animal model of thoracic cord paralysis resulting from covered stent placement and investigate the molecular basis of injury. Methods: A rabbit model of thoracic endovascular repair was created as follows: animals were treated with aortography alone (Control, n ¼ 5) or thoracic aortic stent (n ¼ 6). Each animal was scored in the postoperative period by the Tarlov scale …

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