Display options
Cite
Rudnick MR, Berns JS, Cohen RM, et al. Contrast media-associated nephrotoxicity. Curr Opin Nephrol Hypertens. 1996;5(2):127-33doi: 10.1097/00041552-199603000-00005.
Rudnick, M. R., Berns, J. S., Cohen, R. M., & Goldfarb, S. (1996). Contrast media-associated nephrotoxicity. Current opinion in nephrology and hypertension, 5(2), 127-33. https://doi.org/10.1097/00041552-199603000-00005
Rudnick, M R, et al. "Contrast media-associated nephrotoxicity." Current opinion in nephrology and hypertension vol. 5,2 (1996): 127-33. doi: https://doi.org/10.1097/00041552-199603000-00005
Rudnick MR, Berns JS, Cohen RM, Goldfarb S. Contrast media-associated nephrotoxicity. Curr Opin Nephrol Hypertens. 1996 Mar;5(2):127-33. doi: 10.1097/00041552-199603000-00005. PMID: 8744533.
Copy Download .nbib Format: NLM
Share it on

Curr Opin Nephrol Hypertens. 1996 Mar;5(2):127-33. doi: 10.1097/00041552-199603000-00005.

Contrast media-associated nephrotoxicity.

Current opinion in nephrology and hypertension

M R Rudnick, J S Berns, R M Cohen, S Goldfarb

Affiliations

  1. Department of Medicine, Graduate Hospital, Philadelphia, Pennsylvania 19146, USA.

PMID: 8744533 DOI: 10.1097/00041552-199603000-00005

Abstract

Contrast media-associated nephrotoxicity continues to be a common cause of acute renal failure. We review recent developments in our understanding of the pathogenesis of this complication, focusing on the role of vasoactive substances which include adenosine, endothelium-derived relaxing factor, and endothelin. An overview of clinical features is presented with an emphasis on the value of low osmolar contrast media in azotemic patients. Prophylactic strategies are reviewed focusing on saline hydration alone, vasoactive pharmacological agents, theophylline, 'prophylactic hemodialysis', and possible differences in how these maneuvers affect diabetic and non-diabetic azotemic patients are discussed.

Substances

MeSH terms

Publication Types