Clin Cardiol. 1997 Mar;20(3):196-200. doi: 10.1002/clc.4960200304.

Depression and coronary heart disease: a review for cardiologists.

Clinical cardiology

R M Carney, K E Freedland, Y I Sheline, E S Weiss

PMID: 9068903 PMCID: PMC6655605 DOI: 10.1002/clc.4960200304
Free PMC Article

Abstract

Major depression is a common comorbid condition in patients with coronary heart disease (CHD). Although mild emotional distress may be a normal reaction to myocardial infarction or other manifestations of CHD, major depression should not be considered a normal reaction, nor should it be ignored. Major depression is a debilitating comorbid disorder that can seriously complicate recovery and increase the risks of further cardiac morbidity and mortality. Fortunately, it is one that can be successfully treated in the majority of cases. The purpose of this review is to present the evidence for the negative prognostic effects of depression in cardiac patients and to discuss methods for assessing and treating depression in these patients.

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MeSH terms

• Coronary Disease / complications
• Coronary Disease / psychology
• Depressive Disorder / complications
• Depressive Disorder / diagnosis
• Depressive Disorder / drug therapy
• Humans
• Prognosis

Publication Types

• Journal Article
• Research Support, U.S. Gov't, P.H.S.
• Review

Grant support

• 2 RO1 HL42427-04/HL/NHLBI NIH HHS/United States
• 5RO1 MH51419-02/MH/NIMH NIH HHS/United States

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