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Showing 13 to 15 of 15 entries
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Practical application of mammalian cytochrome P450.

Journal of bioscience and bioengineering

Sakaki T, Inouye K.
PMID: 16232916
J Biosci Bioeng. 2000;90(6):583-90. doi: 10.1263/jbb.90.583.

Heterologous expression systems play an important role in the analysis of structure-function relationships of mammalian P450s. In addition, these expression systems allow practical application of mammalian P450s. Genetically engineered fused enzymes between mammalian P450 and yeast NADPH-P450 reductase have...

Steroidogenic electron-transfer factors and their diseases.

Annals of pediatric endocrinology & metabolism

Miller WL.
PMID: 34610701
Ann Pediatr Endocrinol Metab. 2021 Sep;26(3):138-148. doi: 10.6065/apem.2142154.077. Epub 2021 Sep 30.

Most steroidogenesis disorders are caused by mutations in genes encoding the steroidogenic enzymes, but work in the past 20 years has identified related disorders caused by mutations in the genes encoding the cofactors that transport electrons from NADPH to...

Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding.

Biochemistry

Jay N, Duffy SR, Estrada DF.
PMID: 34979083
Biochemistry. 2022 Jan 18;61(2):57-66. doi: 10.1021/acs.biochem.1c00770. Epub 2022 Jan 03.

The improper maintenance of the bioactivated form of vitamin-D (1α,25(OH)

Showing 13 to 15 of 15 entries