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Showing 925 to 936 of 936 entries
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Distribution of virulence factors, antimicrobial resistance genes and phylogenetic relatedness among Shiga toxin-producing Escherichia coli serogroup O91 from human infections.

International journal of medical microbiology : IJMM

Nüesch-Inderbinen M, Stevens MJA, Cernela N, Müller A, Biggel M, Stephan R.
PMID: 34757276
Int J Med Microbiol. 2021 Oct 26;311(8):151541. doi: 10.1016/j.ijmm.2021.151541. Epub 2021 Oct 26.

Shiga toxin-producing Escherichia coli (STEC) belonging to the serogroup O91 are among the most common non-O157 STEC serogroups associated with human illness in Europe. This study aimed to analyse the virulence factors, antimicrobial resistance genes and phylogenetic relatedness among...

Distribution of virulence factors, antimicrobial resistance genes and phylogenetic relatedness among Shiga toxin-producing Escherichia coli serogroup O91 from human infections.

International journal of medical microbiology : IJMM

Nüesch-Inderbinen M, Stevens MJA, Cernela N, Müller A, Biggel M, Stephan R.
PMID: 34757276
Int J Med Microbiol. 2021 Oct 26;311(8):151541. doi: 10.1016/j.ijmm.2021.151541. Epub 2021 Oct 26.

Shiga toxin-producing Escherichia coli (STEC) belonging to the serogroup O91 are among the most common non-O157 STEC serogroups associated with human illness in Europe. This study aimed to analyse the virulence factors, antimicrobial resistance genes and phylogenetic relatedness among...

Pharmacokinetics of Tobramycin Administered at the Beginning of Intermittent Hemodialysis Session (ESRD Study).

Canadian journal of kidney health and disease

Giroux M, Bouchard N, Henderson A, Lam L, Tran VAS, Projean D, Tessier JF, Lepage L, Gavra P, Ouellet G, Vallée M, Lafrance JP.
PMID: 33680482
Can J Kidney Health Dis. 2021 Feb 19;8:2054358120987061. doi: 10.1177/2054358120987061. eCollection 2021.

BACKGROUND AND OBJECTIVES: There is a renewed interest in the successful use of aminoglycosides due to increasing resistance in gram-negative infections. Few studies to date have examined the pharmacokinetics (PK) of intradialytic infusions of tobramycin. This study sought to...

Prevalence of Genes Encoding Aminoglycoside-Modifying Enzymes and armA among Acinetobacter baumannii Clinical Isolates in Alexandria, Egypt.

Infectious disorders drug targets

ELsheredy A, Yousif Z, Elghazzawi E, Elmenshawy A, Ghazal A.
PMID: 33632111
Infect Disord Drug Targets. 2021;21(8):e300821191828. doi: 10.2174/1871526521666210225113041.

INTRODUCTION: Acinetobacter baumannii (A.baumannii) is a ubiquitous pathogen responsible for serious infections in hospitalized patients with a high propensity to develop resistance to antimicrobial agents. The study aimed to determine the antimicrobial resistance patterns and the prevalence of aminoglycoside...

Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.

JCI insight

Kenyon EJ, Kirkwood NK, Kitcher SR, Goodyear RJ, Derudas M, Cantillon DM, Baxendale S, de la Vega de León A, Mahieu VN, Osgood RT, Wilson CD, Bull JC, Waddell SJ, Whitfield TT, Ward SE, Kros CJ, Richardson GP.
PMID: 33735112
JCI Insight. 2021 Apr 08;6(7). doi: 10.1172/jci.insight.145704.

To identify small molecules that shield mammalian sensory hair cells from the ototoxic side effects of aminoglycoside antibiotics, 10,240 compounds were initially screened in zebrafish larvae, selecting for those that protected lateral-line hair cells against neomycin and gentamicin. When...

Study of class 1 integrons and plasmid profile among multiple drug resistant uropathogenic Escherichia coli.

Pakistan journal of pharmaceutical sciences

Javed S, Mirani ZA, Pirzada ZA.
PMID: 33867342
Pak J Pharm Sci. 2020 Nov;33(6):2643-2649.

The emergence of multidrug resistance in uropathogenic Escherichia coli (UPEC) is associated with the presence of drug resistant plasmids and integrons which facilitate horizontal gene transfer which impose serious challenges in patients with urinary tract infections (UTIs). The proposed...

Distribution of virulence factors, antimicrobial resistance genes and phylogenetic relatedness among Shiga toxin-producing Escherichia coli serogroup O91 from human infections.

International journal of medical microbiology : IJMM

Nüesch-Inderbinen M, Stevens MJA, Cernela N, Müller A, Biggel M, Stephan R.
PMID: 34757276
Int J Med Microbiol. 2021 Dec;311(8):151541. doi: 10.1016/j.ijmm.2021.151541. Epub 2021 Oct 26.

Shiga toxin-producing Escherichia coli (STEC) belonging to the serogroup O91 are among the most common non-O157 STEC serogroups associated with human illness in Europe. This study aimed to analyse the virulence factors, antimicrobial resistance genes and phylogenetic relatedness among...

Genomic insights of Acinetobacter baumannii ST374 reveal wide and increasing resistome and virulome.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Fedrigo NH, Xavier DE, Cerdeira L, Fuga B, Marini PVB, Shinohara DR, Carrara-Marroni FE, Lincopan N, Tognim MCB.
PMID: 34801753
Infect Genet Evol. 2021 Nov 19;97:105148. doi: 10.1016/j.meegid.2021.105148. Epub 2021 Nov 19.

WGS-based surveillance has significantly improved the ability to track global spread and emergence of multidrug-resistant clones of clinically relevant pathogens. In this study, we performed the genomic characterization and comparative analysis of an Acinetobacter baumannii (strain Ac56) belonging to...

Outbreaks of Streptococcus gallolyticus subsp. pasteurianus in goslings characterized by central nervous symptoms.

Avian diseases

Hess C, Jandreski-Cvetkovic D, Liebhart D, Bilic I, Hess M.
PMID: 33284329
Avian Dis. 2020 Dec 07; doi: 10.1637/aviandiseases-D-20-00101. Epub 2020 Dec 07.

SummaryThe present report describes outbreaks of Streptococcus gallolyticus subsp. pasteurianus in young geese flocks in Austria. The flocks, which comprised 160-1450 goslings of 2 to 3 weeks of age, experienced increased mortalities The clinical signs were characterized by severe...

Identification and characterization of class 1 integrons among multidrug-resistant uropathogenic Escherichia coli strains in Mexico.

Microbial pathogenesis

González-Villalobos E, Ribas-Aparicio RM, Belmont-Monroy L, Aparicio-Ozores G, Manjarrez-Hernández HÁ, Gavilanes-Parra S, Balcázar JL, Molina-López J.
PMID: 34871727
Microb Pathog. 2021 Dec 03;162:105348. doi: 10.1016/j.micpath.2021.105348. Epub 2021 Dec 03.

This study aimed to identify and characterize integrons among multidrug-resistant (MDR) uropathogenic Escherichia coli (UPEC) from outpatients in Mexico City, Mexico. PCR assays were used to screen for the presence of class 1, 2 and 3 integrons, whose PCR...

Genomic insights of Acinetobacter baumannii ST374 reveal wide and increasing resistome and virulome.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Fedrigo NH, Xavier DE, Cerdeira L, Fuga B, Marini PVB, Shinohara DR, Carrara-Marroni FE, Lincopan N, Tognim MCB.
PMID: 34801753
Infect Genet Evol. 2021 Nov 19;97:105148. doi: 10.1016/j.meegid.2021.105148. Epub 2021 Nov 19.

WGS-based surveillance has significantly improved the ability to track global spread and emergence of multidrug-resistant clones of clinically relevant pathogens. In this study, we performed the genomic characterization and comparative analysis of an Acinetobacter baumannii (strain Ac56) belonging to...

Therapeutic Drug Monitoring of Antibiotics in Critically Ill Patients: Current Practice and Future Perspectives With a Focus on Clinical Outcome.

Therapeutic drug monitoring

Koch BCP, Muller AE, Hunfeld NGM, de Winter BCM, Ewoldt TMJ, Abdulla A, Endeman H.
PMID: 34772892
Ther Drug Monit. 2022 Feb 01;44(1):11-18. doi: 10.1097/FTD.0000000000000942.

PURPOSE: Early initiation of antibiotics is essential for ameliorating infections in critically ill patients. The correct dosage of antibiotics is imperative to ensure their adequate exposure. Critically ill patients have altered pharmacokinetic parameters and are often infected by less...

Showing 925 to 936 of 936 entries