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Showing 25 to 36 of 38 entries
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The history of barbiturates a century after their clinical introduction.

Neuropsychiatric disease and treatment

López-Muñoz F, Ucha-Udabe R, Alamo C.
PMID: 18568113
Neuropsychiatr Dis Treat. 2005 Dec;1(4):329-43.

The present work offers an analysis of the historical development of the discovery and use of barbiturates in the field of psychiatry and neurology, a century after their clinical introduction. Beginning with the synthesis of malonylurea by von Baeyer...

Amobarbital evaluation of neurobehavioral function prior to therapeutic occlusion of brain arteriovenous malformations: a new neuropsychological procedure.

Applied neuropsychology

Lee GP, Meador KJ, Murro AM, Bauzá-Armstrong JA, Loring DW, Gover CB, Drane DL.
PMID: 16318539
Appl Neuropsychol. 1996 Feb;3(1):1-7. doi: 10.1207/s15324826an0301_1.

Because untreated arteriovenous malformations (AVMs) frequently result in some form of permanent neurological complication, treatment of AVMs is aggressively pursued A relatively new treatment consists of sending micropellets into blood vessels supplying the AVM core to block blood flow...

Use of Lorazepam in drug-assisted interviews: two cases of dissociative amnesia.

Psychiatry investigation

Lee SS, Park S, Park SS.
PMID: 22216050
Psychiatry Investig. 2011 Dec;8(4):377-80. doi: 10.4306/pi.2011.8.4.377. Epub 2011 Nov 03.

Drug-assisted interviews are useful for psychiatric diagnosis and treatment. However, amobarbital, a typical medication used for this purpose, is associated with elevated risk of respiratory depression. Benzodiazepines are good substitutes for amobarbital, with similar therapeutic effects and fewer complications....

In vitro screening for anticonvulsant-induced teratogenesis: Structure-activity relationships in the barbiturate and branched chain carboxylic acid classes.

Toxicology in vitro : an international journal published in association with BIBRA

Regan CM, Larsson OM, Martin ML, Schousboe A, Williams DC.
PMID: 20732000
Toxicol In Vitro. 1991;5(1):77-82. doi: 10.1016/0887-2333(91)90050-n.

The ability of in vitro antiproliferative and cytotoxicity assay systems to discriminate teratogenic potential in closely related anticonvulsant agents is described. A non-teratogenic analogue of valproate-valpramide-had no antiproliferative effect in C6 glioma over the concentration range in which it...

Functional magnetic resonance imaging for language mapping in temporal lobe epilepsy.

Epilepsy research and treatment

Wang A, Peters TM, de Ribaupierre S, Mirsattari SM.
PMID: 22934161
Epilepsy Res Treat. 2012;2012:198183. doi: 10.1155/2012/198183. Epub 2012 Jul 25.

Functional magnetic resonance imaging (fMRI) is a noninvasive technique that is increasingly used to understand the cerebral cortical networks and organizations. In this paper, we describe the role of fMRI for mapping language networks in the presurgical workup of...

Preoperative evaluation for epilepsy surgery: Process improvement.

Neurology. Clinical practice

Drees C, Sillau S, Brown MG, Abosch A.
PMID: 30107011
Neurol Clin Pract. 2017 Jun;7(3):205-213. doi: 10.1212/CPJ.0000000000000357.

BACKGROUND: Epilepsy surgery (ES) can improve seizure outcome. A prolonged duration of presurgical evaluation contributes to epilepsy-related morbidity and mortality. We introduced process changes to decrease evaluation time (ET) and increase ES numbers (excluding vagus nerve stimulation).METHODS: The University...

Intracarotid amobarbital disrupts synchronous and nested oscillatory activity ipsilateral to injection.

Epilepsy & behavior case reports

Young JJ, Friedman JS, Oxley TJ, Palmese C, Panov F, Ghatan S, Fifi JT, Marcuse LV.
PMID: 30013931
Epilepsy Behav Case Rep. 2018 Apr 25;10:25-28. doi: 10.1016/j.ebcr.2018.04.003. eCollection 2018.

The mechanism of amobarbital action during the intracarotid amobarbital procedure is poorly understood. We report a patient case who underwent IAP while implanted with bilateral stereo-EEG. We analyzed the spectral power, phase amplitude coupling, and cluster-phase group synchrony during...

Seizure in Patient with Neurofibromatosis and Amygdala Low-Grade Glioma.

World neurosurgery

Carnevale JA, Goldberg JL, Schwartz T.
PMID: 34600159
World Neurosurg. 2022 Jan;157:54-55. doi: 10.1016/j.wneu.2021.09.097. Epub 2021 Sep 29.

A 31-year-old male with history of bipolar disorder, suicidal attempts requiring inpatient hospitalization, and seizures on antiepileptic medications presented with increasing seizure frequency. He was neurologically intact yet had multiple facial, axillary, and inguinal flat pigmented macules (cafe au...

Electrical Wada for pre-surgical memory testing: a case report.

Epileptic disorders : international epilepsy journal with videotape

Kaestner E, Pedersen NP, Hu R, Vosoughi A, Alwaki A, Ruiz AR, Staikova E, Hewitt KC, Epstein C, McDonald CR, Gross RE, Drane DL.
PMID: 34874269
Epileptic Disord. 2021 Dec 07; doi: 10.1684/epd.2021.1390. Epub 2021 Dec 07.

We report a case study of a surgical candidate, a 51-year-old woman with left temporal lobe epilepsy, who failed a left injection intracarotid amobarbital procedure (e.g., Wada test), scoring 0 of 8 items. This raised concerns for postoperative memory...

Action of amobarbital on microsomal and mitochondrial respiratory state in perfused rat liver with and without phenobarbital induction.

FEBS letters

Brauser B, Sies H, Bücher T.
PMID: 11946302
FEBS Lett. 1969 Jan;2(3):170-172. doi: 10.1016/0014-5793(69)80009-8.

No abstract available.

Implementation of Intraoperative Neurophysiological Monitoring during Endovascular Procedures in the Central Nervous System.

Interventional neurology

Martinez Piñeiro A, Cubells C, Garcia P, Castaño C, Dávalos A, Coll-Canti J.
PMID: 26019712
Interv Neurol. 2015 Mar;3(2):85-100. doi: 10.1159/000371453.

BACKGROUND AND OBJECTIVE: Intraoperative monitoring (IOM) has been used in different surgical disciplines since the 1980s. Nonetheless, regular routine use of IOM in interventional neuroradiology units has only been reported in a few centers. The aim of this study...

The Wada test in the evaluation for epilepsy surgery.

Neurosciences (Riyadh, Saudi Arabia)

Loring DW, Meador KJ, Westerveld M.
PMID: 24276596
Neurosciences (Riyadh). 2000 Oct;5(4):203-8.

The Wada test is the standard part of the pre-operative evaluation for epilepsy surgery. The procedure involves the slow injection of sodium amobarbital (typically 100-500mg) into the internal carotid artery following a transfermoral approach. The amobarbital anesthetizes the anterior...

Showing 25 to 36 of 38 entries