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Showing 13 to 24 of 94 entries
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Influence of Body Weight Category on Outcomes in Candidemia Patients Treated With Anidulafungin.

Journal of pharmacy practice

Hutton M, Kenney RM, Vazquez JA, Davis SL.
PMID: 32648506
J Pharm Pract. 2020 Jul 10;897190020938219. doi: 10.1177/0897190020938219. Epub 2020 Jul 10.

BACKGROUND: Case reports and pharmacokinetic data suggest off-label echinocandin dosing may be needed to reach adequate serum concentrations in obese patients. Few outcome studies exist evaluating this population.OBJECTIVES: Of this study were to (1) determine the association of body...

Deacylation of Echinocandin B by Streptomyces species: a novel method for the production of Echinocandin B nucleus.

3 Biotech

Shivakumar MC, Manohar S, Ishwar B, Raghu P, Savitha J.
PMID: 31696017
3 Biotech. 2019 Nov;9(11):412. doi: 10.1007/s13205-019-1946-7. Epub 2019 Oct 23.

Anidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by

Echinocandins for management of invasive candidiasis in patients with liver disease and liver transplantation.

Infection and drug resistance

Yeoh SF, Lee TJ, Chew KL, Lin S, Yeo D, Setia S.
PMID: 29881298
Infect Drug Resist. 2018 May 30;11:805-819. doi: 10.2147/IDR.S165676. eCollection 2018.

No abstract available.

Assessment of nonreleasing antifungal surface coatings bearing covalently attached pharmaceuticals.

Biointerphases

Naderi J, Griesser HJ, Coad BR.
PMID: 34794317
Biointerphases. 2021 Nov 18;16(6):061001. doi: 10.1116/6.0001099.

There are many reports of antimicrobial coatings bearing immobilized active agents on surfaces; however, strong analytical evidence is required to verify that the agents are indeed covalently attached to the surface. In the absence of such evidence, antimicrobial activity...

Susceptibility testing of Prototheca bovis isolates from cases of bovine mastitis using the CLSI reference broth microdilution method and the Sensititre YeastOne colorimetric panel.

Medical mycology

Álvarez-Pérez S, Anega B, Díaz-de-Tuesta JA, González-Martín JV, Riesgo-Martínez M, García ME, Blanco JL.
PMID: 34643716
Med Mycol. 2021 Dec 03;59(12):1257-1261. doi: 10.1093/mmy/myab063.

A total of 62 Prototheca bovis isolates from cases of bovine mastitis were tested for susceptibility to different antifungal compounds by the Clinical and Laboratory Standards Institute (CLSI) reference microdilution method and a commercial colorimetric microdilution panel (Sensititre YeastOne)....

In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against .

Pharmaceutics

Caballero U, Eraso E, Quindós G, Jauregizar N.
PMID: 34575409
Pharmaceutics. 2021 Aug 25;13(9). doi: 10.3390/pharmaceutics13091333.

Treatment of invasive infections caused by

DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis.

Antimicrobial agents and chemotherapy

Ambati S, Pham T, Lewis ZA, Lin X, Meagher RB.
PMID: 34633846
Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0146721. doi: 10.1128/AAC.01467-21. Epub 2021 Oct 11.

Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall, exopolysaccharide matrix, and biofilm rich in oligoglucans and oligomannans help

Functional expression of an echinocandin B deacylase from Actinoplanes utahensis in Escherichia coli.

International journal of biological macromolecules

Zou SP, Han X, Zhu HY, Sheng Q, Tang H, Liu ZQ, Zheng YG.
PMID: 34339787
Int J Biol Macromol. 2021 Sep 30;187:850-857. doi: 10.1016/j.ijbiomac.2021.07.146. Epub 2021 Jul 30.

Echinocandin B deacylase (ECBD) from Actinoplanes utahensis can be applied to produce echinocandin B nucleus (ECBN), an essential intermediate of the echinocandins antifungal drugs such as anidulafungin. To date, the expression of ECBD has been limited to Streptomyces. To...

Epidemiology of echinocandin resistance in .

Current fungal infection reports

Grossman NT, Chiller TM, Lockhart SR.
PMID: 29780439
Curr Fungal Infect Rep. 2014 Dec;8(4):243-248. doi: 10.1007/s12281-014-0209-7. Epub 2014 Sep 21.

Echinocandins are the newest antifungal agents approved for use in treating

Successful Treatment of Azole-Resistant Candida Esophagitis in an Immunocompromised Pregnant Woman Using Anidulafungin.

The Annals of pharmacotherapy

Blackwell CO, Sheth AN, Nguyen ML, Badell ML.
PMID: 28660773
Ann Pharmacother. 2017 Nov;51(11):1033-1034. doi: 10.1177/1060028017717998. Epub 2017 Jun 29.

No abstract available.

Anidulafungin: advantage for the newcomer?.

Expert review of clinical pharmacology

Rüping MJ, Vehreschild JJ, Farowski F, Cornely OA.
PMID: 24422646
Expert Rev Clin Pharmacol. 2008 Mar;1(2):207-16. doi: 10.1586/17512433.1.2.207.

Anidulafungin is the most recently approved compound of the echinocandin antifungal class. Its mode of action is the noncompetitive inhibition of β-(1,3)-D-glucan synthesis. Potent fungicidal activity has been demonstrated against many Candida spp., including non-albicansCandida spp. and fluconazole-resistant strains,...

Candida utilis catheter-related bloodstream infection.

Medical mycology case reports

Scoppettuolo G, Donato C, De Carolis E, Vella A, Vaccaro L, La Greca A, Fantoni M.
PMID: 25473600
Med Mycol Case Rep. 2014 Nov 04;6:70-2. doi: 10.1016/j.mmcr.2014.10.003. eCollection 2014 Oct.

Central venous catheter-related fungemia are increasing in the last years, also due to rare fungi. We report the case of a Candida utilis catheter-related bloodstream infection in a patient with metastatic carcinoma of the bladder and a long term...

Showing 13 to 24 of 94 entries