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Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model.

Autoimmunity

Di Liddo R, Valente S, Taurone S, Zwergel C, Marrocco B, Turchetta R, Conconi MT, Scarpa C, Bertalot T, Schrenk S, Mai A, Artico M.
PMID: 26789595
Autoimmunity. 2016 Jan 20;1-11. doi: 10.3109/08916934.2015.1134510. Epub 2016 Jan 20.

Among epigenetic enzymes, histone deacetylases (HDACs) are responsible for regulating the expression of an extensive array of genes by reversible deacetylation of nuclear histones as well as a large number of non-histone proteins. Initially proposed for cancer therapy, recently...

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Di Liddo R, Valente S, Taurone S, et al. Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model. Autoimmunity. 2016;1-11doi: 10.3109/08916934.2015.1134510.
Di Liddo, R., Valente, S., Taurone, S., Zwergel, C., Marrocco, B., Turchetta, R., Conconi, M. T., Scarpa, C., Bertalot, T., Schrenk, S., Mai, A., & Artico, M. (2016). Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model. Autoimmunity, 1-11. https://doi.org/10.3109/08916934.2015.1134510
Di Liddo, Rosa, et al. "Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model." Autoimmunity vol. (2016): 1-11. doi: https://doi.org/10.3109/08916934.2015.1134510
Di Liddo R, Valente S, Taurone S, Zwergel C, Marrocco B, Turchetta R, Conconi MT, Scarpa C, Bertalot T, Schrenk S, Mai A, Artico M. Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model. Autoimmunity. 2016 Jan 20;1-11. doi: 10.3109/08916934.2015.1134510. Epub 2016 Jan 20. PMID: 26789595.
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Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs.

Frontiers in immunology

Ramos I, Fernandez-Sesma A.
PMID: 26257731
Front Immunol. 2015 Jul 20;6:361. doi: 10.3389/fimmu.2015.00361. eCollection 2015.

Infection by influenza A viruses (IAV) is frequently characterized by robust inflammation that is usually more pronounced in the case of avian influenza. It is becoming clearer that the morbidity and pathogenesis caused by IAV are consequences of this...

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Ramos I, Fernandez-Sesma A. Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs. Front Immunol. 2015;6:361doi: 10.3389/fimmu.2015.00361.
Ramos, I., & Fernandez-Sesma, A. (2015). Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs. Frontiers in immunology, 6361. https://doi.org/10.3389/fimmu.2015.00361
Ramos, Irene, and Fernandez-Sesma, Ana. "Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs." Frontiers in immunology vol. 6 (2015): 361. doi: https://doi.org/10.3389/fimmu.2015.00361
Ramos I, Fernandez-Sesma A. Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs. Front Immunol. 2015 Jul 20;6:361. doi: 10.3389/fimmu.2015.00361. eCollection 2015. PMID: 26257731; PMCID: PMC4507467.
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Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy.

Journal of cutaneous and aesthetic surgery

Goh CL, Noppakun N, Micali G, Azizan NZ, Boonchai W, Chan Y, Cheong WK, Chiu PC, Etnawati K, Gulmatico-Flores Z, Foong H, Kubba R, Paz-Lao P, Lee YY, Loo S, Modi F, Nguyen TH, Pham TL, Shih YH, Sitohang IB, Wong SN.
PMID: 27398008
J Cutan Aesthet Surg. 2016 Apr-Jun;9(2):85-92. doi: 10.4103/0974-2077.184043.

Conventional acne treatment presents several challenges such as intolerable side effects and antibiotic resistance. Dermocosmetic products may be used to reduce these unwanted effects. Dermocosmetics include skin cleansers, topical sebum-controllers, skin antimicrobial/anti-inflammatory agents, moisturizers, sunscreens, and camouflage products. Appropriate...

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Goh CL, Noppakun N, Micali G, et al. Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy. J Cutan Aesthet Surg. 2016;9(2):85-92doi: 10.4103/0974-2077.184043.
Goh, C. L., Noppakun, N., Micali, G., Azizan, N. Z., Boonchai, W., Chan, Y., Cheong, W. K., Chiu, P. C., Etnawati, K., Gulmatico-Flores, Z., Foong, H., Kubba, R., Paz-Lao, P., Lee, Y. Y., Loo, S., Modi, F., Nguyen, T. H., Pham, T. L., Shih, Y. H., Sitohang, I. B., & Wong, S. N. (2016). Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy. Journal of cutaneous and aesthetic surgery, 9(2), 85-92. https://doi.org/10.4103/0974-2077.184043
Goh, Chee Leok, et al. "Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy." Journal of cutaneous and aesthetic surgery vol. 9,2 (2016): 85-92. doi: https://doi.org/10.4103/0974-2077.184043
Goh CL, Noppakun N, Micali G, Azizan NZ, Boonchai W, Chan Y, Cheong WK, Chiu PC, Etnawati K, Gulmatico-Flores Z, Foong H, Kubba R, Paz-Lao P, Lee YY, Loo S, Modi F, Nguyen TH, Pham TL, Shih YH, Sitohang IB, Wong SN. Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy. J Cutan Aesthet Surg. 2016 Apr-Jun;9(2):85-92. doi: 10.4103/0974-2077.184043. PMID: 27398008; PMCID: PMC4924420.
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Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease.

World journal of hepatology

Heebøll S, Thomsen KL, Pedersen SB, Vilstrup H, George J, Grønbæk H.
PMID: 24799987
World J Hepatol. 2014 Apr 27;6(4):188-98. doi: 10.4254/wjh.v6.i4.188.

The prevalence of obesity and related conditions like non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and therapeutic options are limited. Alternative treatment options are therefore intensively sought after. An interesting candidate is the natural polyphenol resveratrol (RSV) that...

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Heebøll S, Thomsen KL, Pedersen SB, et al. Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease. World J Hepatol. 2014;6(4):188-98doi: 10.4254/wjh.v6.i4.188.
Heebøll, S., Thomsen, K. L., Pedersen, S. B., Vilstrup, H., George, J., & Grønbæk, H. (2014). Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease. World journal of hepatology, 6(4), 188-98. https://doi.org/10.4254/wjh.v6.i4.188
Heebøll, Sara, et al. "Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease." World journal of hepatology vol. 6,4 (2014): 188-98. doi: https://doi.org/10.4254/wjh.v6.i4.188
Heebøll S, Thomsen KL, Pedersen SB, Vilstrup H, George J, Grønbæk H. Effects of resveratrol in experimental and clinical non-alcoholic fatty liver disease. World J Hepatol. 2014 Apr 27;6(4):188-98. doi: 10.4254/wjh.v6.i4.188. PMID: 24799987; PMCID: PMC4009474.
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Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana.

Biomolecules & therapeutics

Li W, Yan XT, Sun YN, Ngan TT, Shim SH, Kim YH, Sovacool BK, Axsen J, Sorrell S.
PMID: 25143813
Biomol Ther (Seoul). 2014 Jul;22(4):334-40. doi: 10.4062/biomolther.2014.047.

In this study, 23 oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. The NF-κB inhibitory activity of the isolated compounds was measured in TNFα-treated HepG2 cells using a luciferase reporter system. Compounds...

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Li W, Yan XT, Sun YN, et al. Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana. Biomol Ther (Seoul). 2014;22(4):334-40doi: 10.4062/biomolther.2014.047.
Li, W., Yan, X. T., Sun, Y. N., Ngan, T. T., Shim, S. H., Kim, Y. H., Sovacool, B. K., Axsen, J., & Sorrell, S. (2014). Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana. Biomolecules & therapeutics, 22(4), 334-40. https://doi.org/10.4062/biomolther.2014.047
Li, Wei, et al. "Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana." Biomolecules & therapeutics vol. 22,4 (2014): 334-40. doi: https://doi.org/10.4062/biomolther.2014.047
Li W, Yan XT, Sun YN, Ngan TT, Shim SH, Kim YH, Sovacool BK, Axsen J, Sorrell S. Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana. Biomol Ther (Seoul). 2014 Jul;22(4):334-40. doi: 10.4062/biomolther.2014.047. PMID: 25143813; PMCID: PMC4131524.
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Musculoskeletal pelvic pain in a pediatric and adolescent gynecology practice.

Journal of pediatric and adolescent gynecology

Schroeder B, Sanfilippo JS, Hertweck SP.
PMID: 10869976
J Pediatr Adolesc Gynecol. 2000 May;13(2):90. doi: 10.1016/s1083-3188(00)00019-x.

Background: Pelvic pain is a common complaint encountered in pediatric and adolescent gynecology. Etiologies are similar to those found in adult women, but the incidence and presentations vary with age. The purpose of this study is to review musculoskeletal...

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Schroeder B, Sanfilippo JS, Hertweck SP. Musculoskeletal pelvic pain in a pediatric and adolescent gynecology practice. J Pediatr Adolesc Gynecol. 2000;13(2):90doi: 10.1016/s1083-3188(00)00019-x.
Schroeder, B., Sanfilippo, J. S., & Hertweck, S. P. (2000). Musculoskeletal pelvic pain in a pediatric and adolescent gynecology practice. Journal of pediatric and adolescent gynecology, 13(2), 90. https://doi.org/10.1016/s1083-3188(00)00019-x
Schroeder, et al. "Musculoskeletal pelvic pain in a pediatric and adolescent gynecology practice." Journal of pediatric and adolescent gynecology vol. 13,2 (2000): 90. doi: https://doi.org/10.1016/s1083-3188(00)00019-x
Schroeder B, Sanfilippo JS, Hertweck SP. Musculoskeletal pelvic pain in a pediatric and adolescent gynecology practice. J Pediatr Adolesc Gynecol. 2000 May;13(2):90. doi: 10.1016/s1083-3188(00)00019-x. PMID: 10869976.
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Synthesis and anti-inflammatory activity of N-substituted 2-oxo-2H-1-benzopyran-3-carboxamides and their 2-iminoanalogues.

European journal of medicinal chemistry

Bylov IE, Vasylyev MV, Bilokin YV.
PMID: 10889323
Eur J Med Chem. 1999 Nov 01;34(11):997-1001. doi: 10.1016/s0223-5234(99)00119-1.

Aseries of N-arylsubstituted 2-imino-2H-1-benzopyran-3-carboxamides 3a and b and 2-oxo-2H-1-benzopyran-3-carboxamides 4a-h were synthesized and evaluated for their anti-inflammatory activity in carrageenan-induced rat paw oedema assays and in acetic acid-induced peritonitis tests in albino rats. The resulting products were found to...

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Bylov IE, Vasylyev MV, Bilokin YV. Synthesis and anti-inflammatory activity of N-substituted 2-oxo-2H-1-benzopyran-3-carboxamides and their 2-iminoanalogues. Eur J Med Chem. 1999;34(11):997-1001doi: 10.1016/s0223-5234(99)00119-1.
Bylov, I. E., Vasylyev, M. V., & Bilokin, Y. V. (1999). Synthesis and anti-inflammatory activity of N-substituted 2-oxo-2H-1-benzopyran-3-carboxamides and their 2-iminoanalogues. European journal of medicinal chemistry, 34(11), 997-1001. https://doi.org/10.1016/s0223-5234(99)00119-1
Bylov, et al. "Synthesis and anti-inflammatory activity of N-substituted 2-oxo-2H-1-benzopyran-3-carboxamides and their 2-iminoanalogues." European journal of medicinal chemistry vol. 34,11 (1999): 997-1001. doi: https://doi.org/10.1016/s0223-5234(99)00119-1
Bylov IE, Vasylyev MV, Bilokin YV. Synthesis and anti-inflammatory activity of N-substituted 2-oxo-2H-1-benzopyran-3-carboxamides and their 2-iminoanalogues. Eur J Med Chem. 1999 Nov 01;34(11):997-1001. doi: 10.1016/s0223-5234(99)00119-1. PMID: 10889323.
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Pediatric patient with systemic lupus erythematosus & congenital acquired immunodeficiency syndrome: An unusual case and a review of the literature.

Pediatric rheumatology online journal

Chalom EC, Rezaee F, Mendelson J.
PMID: 18452619
Pediatr Rheumatol Online J. 2008 May 01;6:7. doi: 10.1186/1546-0096-6-7.

The coexistence of systemic lupus erythematosus (SLE) in patients with congenital human immunodeficiency virus (HIV) infection is rare. This is a case report of a child diagnosed with SLE at nine years of age. She initially did well on...

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Chalom EC, Rezaee F, Mendelson J. Pediatric patient with systemic lupus erythematosus & congenital acquired immunodeficiency syndrome: An unusual case and a review of the literature. Pediatr Rheumatol Online J. 2008;6:7doi: 10.1186/1546-0096-6-7.
Chalom, E. C., Rezaee, F., & Mendelson, J. (2008). Pediatric patient with systemic lupus erythematosus & congenital acquired immunodeficiency syndrome: An unusual case and a review of the literature. Pediatric rheumatology online journal, 67. https://doi.org/10.1186/1546-0096-6-7
Chalom, Elizabeth C, et al. "Pediatric patient with systemic lupus erythematosus & congenital acquired immunodeficiency syndrome: An unusual case and a review of the literature." Pediatric rheumatology online journal vol. 6 (2008): 7. doi: https://doi.org/10.1186/1546-0096-6-7
Chalom EC, Rezaee F, Mendelson J. Pediatric patient with systemic lupus erythematosus & congenital acquired immunodeficiency syndrome: An unusual case and a review of the literature. Pediatr Rheumatol Online J. 2008 May 01;6:7. doi: 10.1186/1546-0096-6-7. PMID: 18452619; PMCID: PMC2390549.
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Clonidine--a potent analgesic adjuvant.

Current opinion in anaesthesiology

Tryba M, Gehling M.
PMID: 17019247
Curr Opin Anaesthesiol. 2002 Oct;15(5):511-7. doi: 10.1097/00001503-200210000-00007.

PURPOSE OF REVIEW: The alpha(2)-adrenoceptor agonist clonidine is one of the most widely investigated substances in anaesthesia and pain therapy. Recently, numerous experimental and clinical studies have allowed a better understanding of its underlying mechanisms of action and interactions...

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Tryba M, Gehling M. Clonidine--a potent analgesic adjuvant. Curr Opin Anaesthesiol. 2002;15(5):511-7doi: 10.1097/00001503-200210000-00007.
Tryba, M., & Gehling, M. (2002). Clonidine--a potent analgesic adjuvant. Current opinion in anaesthesiology, 15(5), 511-7. https://doi.org/10.1097/00001503-200210000-00007
Tryba, Michael, and Gehling, Markus. "Clonidine--a potent analgesic adjuvant." Current opinion in anaesthesiology vol. 15,5 (2002): 511-7. doi: https://doi.org/10.1097/00001503-200210000-00007
Tryba M, Gehling M. Clonidine--a potent analgesic adjuvant. Curr Opin Anaesthesiol. 2002 Oct;15(5):511-7. doi: 10.1097/00001503-200210000-00007. PMID: 17019247.
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Experimental Urinary Tract Infection in Rats Caused by Candida albicans.

Antimicrobial agents and chemotherapy

Miraglia GJ, Renz KJ.
PMID: 16557673
Antimicrob Agents Chemother. 1973 Apr;3(4):474-7. doi: 10.1128/AAC.3.4.474.

The increased clinical use of broad-spectrum antibiotics, immunosuppressives, and anti-inflammatory agents is thought to have contributed to the increased incidence of renal infections due to Candida albicans. To aid in the search for improved anticandidal agents, we developed an...

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Miraglia GJ, Renz KJ. Experimental Urinary Tract Infection in Rats Caused by Candida albicans. Antimicrob Agents Chemother. 1973;3(4):474-7doi: 10.1128/AAC.3.4.474.
Miraglia, G. J., & Renz, K. J. (1973). Experimental Urinary Tract Infection in Rats Caused by Candida albicans. Antimicrobial agents and chemotherapy, 3(4), 474-7. https://doi.org/10.1128/AAC.3.4.474
Miraglia, G J, and Renz, K J. "Experimental Urinary Tract Infection in Rats Caused by Candida albicans." Antimicrobial agents and chemotherapy vol. 3,4 (1973): 474-7. doi: https://doi.org/10.1128/AAC.3.4.474
Miraglia GJ, Renz KJ. Experimental Urinary Tract Infection in Rats Caused by Candida albicans. Antimicrob Agents Chemother. 1973 Apr;3(4):474-7. doi: 10.1128/AAC.3.4.474. PMID: 16557673; PMCID: PMC444437.
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The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review.

Archives of gerontology and geriatrics

Miquel J, Bernd A, Sempere JM, Díaz-Alperi J, Ramírez A.
PMID: 14764309
Arch Gerontol Geriatr. 2002 Feb;34(1):37-46. doi: 10.1016/s0167-4943(01)00194-7.

In agreement with the predictions of the oxygen-stress theory of aging and age-related degenerative diseases, diet supplementation with a number of phenolic or thiolic antioxidants has been able to increase the life span of laboratory animals, protect against senescent...

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Miquel J, Bernd A, Sempere JM, et al. The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review. Arch Gerontol Geriatr. 2002;34(1):37-46doi: 10.1016/s0167-4943(01)00194-7.
Miquel, J., Bernd, A., Sempere, J. M., Díaz-Alperi, J., & Ramírez, A. (2002). The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review. Archives of gerontology and geriatrics, 34(1), 37-46. https://doi.org/10.1016/s0167-4943(01)00194-7
Miquel, J, et al. "The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review." Archives of gerontology and geriatrics vol. 34,1 (2002): 37-46. doi: https://doi.org/10.1016/s0167-4943(01)00194-7
Miquel J, Bernd A, Sempere JM, Díaz-Alperi J, Ramírez A. The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review. Arch Gerontol Geriatr. 2002 Feb;34(1):37-46. doi: 10.1016/s0167-4943(01)00194-7. PMID: 14764309.
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PPARgamma, neuroinflammation, and disease.

Journal of neuroinflammation

Mrak RE, Landreth GE.
PMID: 15285797
J Neuroinflammation. 2004 May 14;1(1):5. doi: 10.1186/1742-2094-1-5.

BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are a class of nuclear transcription factors that are activated by fatty acids and their derivatives. One of these, PPARgamma, regulates responsiveness to insulin in adipose cells, and PPARgamma-activating drugs such as pioglitazone are...

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Mrak RE, Landreth GE. PPARgamma, neuroinflammation, and disease. J Neuroinflammation. 2004;1(1):5doi: 10.1186/1742-2094-1-5.
Mrak, R. E., & Landreth, G. E. (2004). PPARgamma, neuroinflammation, and disease. Journal of neuroinflammation, 1(1), 5. https://doi.org/10.1186/1742-2094-1-5
Mrak, Robert E, and Landreth, Gary E. "PPARgamma, neuroinflammation, and disease." Journal of neuroinflammation vol. 1,1 (2004): 5. doi: https://doi.org/10.1186/1742-2094-1-5
Mrak RE, Landreth GE. PPARgamma, neuroinflammation, and disease. J Neuroinflammation. 2004 May 14;1(1):5. doi: 10.1186/1742-2094-1-5. PMID: 15285797; PMCID: PMC483058.
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Showing 13 to 24 of 943 entries