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Showing 13 to 24 of 6358 entries
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Proliferation and motility of hepatocellular, pancreatic and gastric cancer cells grown in a medium without glucose and arginine, but with galactose and ornithine.

Oncology letters

Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.
PMID: 28454246
Oncol Lett. 2017 Mar;13(3):1276-1280. doi: 10.3892/ol.2017.5568. Epub 2017 Jan 04.

Human primary hepatocytes are able to survive in a medium without glucose and arginine, but supplemented with galactose and ornithine (hepatocyte selection medium; HSM). To address the possibility of the application of HSM in cancer therapy, hepatocellular carcinoma cells,...

Effect of dimethyl fumarate on rats with chronic pancreatitis.

Asian Pacific journal of tropical medicine

Zhang WX, Zhao JH, Ping FM, Liu ZJ, Gu JX, Lu XQ.
PMID: 26972398
Asian Pac J Trop Med. 2016 Mar;9(3):261-4. doi: 10.1016/j.apjtm.2016.01.023. Epub 2016 Jan 11.

OBJECTIVE: To discuss the effect of dimethyl fumarate (DMF) on rats with l-arginine induced chronic pancreatitis (CP).METHODS: Male Wistar rats were given DMF treatment (25 mg/kg) by oral lavage method; then Wistar rats were given the intraperitoneal injection of...

Serine-arginine protein kinase 1 (SRPK1) is elevated in gastric cancer and plays oncogenic functions.

Oncotarget

Xu X, Wei Y, Wang S, Luo M, Zeng H.
PMID: 28977917
Oncotarget. 2017 Jun 28;8(37):61944-61957. doi: 10.18632/oncotarget.18734. eCollection 2017 Sep 22.

Serine-arginine protein kinase 1 (SRPK1) phosphorylates proteins involved in the regulation of several mRNA processing pathways including alternative splicing. SRPK1 has been reported to be over-expressed in multiple cancers including prostate, breast, lung and glioma. Several studies further identified...

Diabetes Associated Metabolomic Perturbations in NOD Mice.

Metabolomics : Official journal of the Metabolomic Society

Grapov D, Fahrmann J, Hwang J, Poudel A, Jo J, Periwal V, Fiehn O, Hara M.
PMID: 25755629
Metabolomics. 2015 Apr;11(2):425-437. doi: 10.1007/s11306-014-0706-2.

Non-obese diabetic (NOD) mice are a widely-used model oftype1 diabetes (T1D). However, not all animals develop overt diabetes. This study examined the circulating metabolomic profiles of NOD mice progressing or not progressing to T1D. Total beta-cell mass was quantified...

Impact of Adiposity and Fat Distribution on the Dynamics of Adrenocorticotropin and Cortisol Rhythms.

Current obesity reports

Roelfsema F, Pereira AM, Veldhuis JD.
PMID: 26626915
Curr Obes Rep. 2014 Dec;3(4):387-95. doi: 10.1007/s13679-014-0118-7.

Obesity impacts many hormonal systems, including pituitary hormones, as well as insulin and leptin. In this review we discuss articles which investigate the influence of obesity on the hypothalamic-pituitary-adrenal (HPA) axis. Different techniques have been used to assess the...

Helicase associated 2 domain is essential for helicase activity of RNA helicase A.

Biochimica et biophysica acta

Xing L, Zhao X, Niu M, Kleiman L.
PMID: 25062910
Biochim Biophys Acta. 2014 Oct;1844(10):1757-64. doi: 10.1016/j.bbapap.2014.07.001. Epub 2014 Jul 23.

RNA helicase A (RHA), a DExD/H box protein, plays critical roles in a wide variety of cellular or viral functions. RHA contains a conserved core helicase domain that is flanked by five other domains. Two double-stranded RNA binding domains...

Conservation of AtTZF1, AtTZF2, and AtTZF3 homolog gene regulation by salt stress in evolutionarily distant plant species.

Frontiers in plant science

D'Orso F, De Leonardis AM, Salvi S, Gadaleta A, Ruberti I, Cattivelli L, Morelli G, Mastrangelo AM.
PMID: 26136754
Front Plant Sci. 2015 Jun 16;6:394. doi: 10.3389/fpls.2015.00394. eCollection 2015.

Arginine-rich tandem zinc-finger proteins (RR-TZF) participate in a wide range of plant developmental processes and adaptive responses to abiotic stress, such as cold, salt, and drought. This study investigates the conservation of the genes AtTZF1-5 at the level of...

Analysis of the clinical and molecular characteristics of a child with achondroplasia: A case report.

Experimental and therapeutic medicine

Liu J, Tang X, Cheng J, Wang L, Yang X, Wang Y.
PMID: 26136890
Exp Ther Med. 2015 May;9(5):1763-1767. doi: 10.3892/etm.2015.2324. Epub 2015 Mar 02.

Achondroplasia (ACH) is a hereditary dwarfism caused by the disturbed proliferation and differentiation of growth plate chondrocytes, followed by impaired endochondral bone growth. ACH is caused by mutations in the gene encoding the transmembrane receptor, fibroblast growth factor receptor...

Inducible HGF-secreting Human Umbilical Cord Blood-derived MSCs Produced via TALEN-mediated Genome Editing Promoted Angiogenesis.

Molecular therapy : the journal of the American Society of Gene Therapy

Chang HK, Kim PH, Cho HM, Yum SY, Choi YJ, Son Y, Lee D, Kang I, Kang KS, Jang G, Cho JY.
PMID: 27434585
Mol Ther. 2016 Sep;24(9):1644-54. doi: 10.1038/mt.2016.120. Epub 2016 Jun 10.

Mesenchymal stem cells (MSCs) promote therapeutic angiogenesis to cure serious vascular disorders. However, their survival period and cytokine-secretory capacity are limited. Although hepatocyte growth factor (HGF) can accelerate the rate of angiogenesis, recombinant HGF is limited because of its...

Coomassie Brilliant Blue G-250 Dye: An Application for Forensic Fingerprint Analysis.

Analytical chemistry

Brunelle E, Le AM, Huynh C, Wingfield K, Halámková L, Agudelo J, Halámek J.
PMID: 28293949
Anal Chem. 2017 Apr 04;89(7):4314-4319. doi: 10.1021/acs.analchem.7b00510. Epub 2017 Mar 24.

The Bradford reagent, comprised of the Coomassie Brilliant Blue G-250 dye, methanol, and phosphoric acid, has been traditionally used for quantifying proteins. Use of this reagent in the Bradford assay relies on the binding of the Coomassie Blue G-250...

Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine.

Frontiers in pharmacology

Ghisalberti CA, Borzì RM, Cetrullo S, Flamigni F, Cairo G.
PMID: 27375482
Front Pharmacol. 2016 Jun 03;7:147. doi: 10.3389/fphar.2016.00147. eCollection 2016.

A reparative approach of disrupted epithelium in obstructive airway diseases, namely asthma and chronic obstructive pulmonary disease (COPD), may afford protection and long-lasting results compared to conventional therapies, e.g., corticosteroids or immunosuppressant drugs. Here, we propose the polyamine spermidine...

Exercise-Associated Hyponatremia: 2017 Update.

Frontiers in medicine

Hew-Butler T, Loi V, Pani A, Rosner MH.
PMID: 28316971
Front Med (Lausanne). 2017 Mar 03;4:21. doi: 10.3389/fmed.2017.00021. eCollection 2017.

Exercise-associated hyponatremia (EAH) was initially described in the 1980s in endurance athletes, and work done since then has conclusively identified that overdrinking beyond thirst and non-osmotic arginine vasopressin release are the most common etiologic factors. In recent years, EAH...

Showing 13 to 24 of 6358 entries