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Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports.

Cases journal

Pisarik P, Kai D.
PMID: 20126318
Cases J. 2009 Sep 15;2:9237. doi: 10.4076/1757-1626-2-9237.

INTRODUCTION: Aspartame may have idiosyncratic toxic effects for some people; however, there are few case reports published in the medical literature. We present two case reports in a pair of siblings, one with a vestibular and the other with...

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Pisarik P, Kai D. Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports. Cases J. 2009;2:9237doi: 10.4076/1757-1626-2-9237.
Pisarik, P., & Kai, D. (2009). Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports. Cases journal, 29237. https://doi.org/10.4076/1757-1626-2-9237
Pisarik, Paul, and Kai, Dasha. "Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports." Cases journal vol. 2 (2009): 9237. doi: https://doi.org/10.4076/1757-1626-2-9237
Pisarik P, Kai D. Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports. Cases J. 2009 Sep 15;2:9237. doi: 10.4076/1757-1626-2-9237. PMID: 20126318; PMCID: PMC2815650.
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Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage.

Journal of food science and technology

Arora S, Shendurse AM, Sharma V, Wadhwa BK, Singh AK.
PMID: 24425980
J Food Sci Technol. 2013 Aug;50(4):770-6. doi: 10.1007/s13197-011-0386-0. Epub 2011 May 05.

In the present study, artificial sweeteners-aspartame, acesulfame-K and binary sweetener blend of aspartame x acesulfame-K were assessed for stability during storage in whey lemon beverage. A solid phase extraction method using C18 cartridges was standardized for the isolation of...

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Arora S, Shendurse AM, Sharma V, et al. Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage. J Food Sci Technol. 2011;50(4):770-6doi: 10.1007/s13197-011-0386-0.
Arora, S., Shendurse, A. M., Sharma, V., Wadhwa, B. K., & Singh, A. K. (2013). Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage. Journal of food science and technology, 50(4), 770-6. https://doi.org/10.1007/s13197-011-0386-0
Arora, Sumit, et al. "Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage." Journal of food science and technology vol. 50,4 (2013): 770-6. doi: https://doi.org/10.1007/s13197-011-0386-0
Arora S, Shendurse AM, Sharma V, Wadhwa BK, Singh AK. Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage. J Food Sci Technol. 2013 Aug;50(4):770-6. doi: 10.1007/s13197-011-0386-0. Epub 2011 May 05. PMID: 24425980; PMCID: PMC3671041.
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Design, formulation and evaluation of nicotine chewing gum.

Advanced biomedical research

Aslani A, Rafiei S.
PMID: 23326788
Adv Biomed Res. 2012;1:57. doi: 10.4103/2277-9175.100175. Epub 2012 Aug 28.

BACKGROUND: Nicotine replacement therapy (NRT) can help smokers to quit smoking. Nicotine chewing gum has attracted the attention from pharmaceutical industries to offer it to consumers as an easily accessible NRT product. However, the bitter taste of such gums...

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Aslani A, Rafiei S. Design, formulation and evaluation of nicotine chewing gum. Adv Biomed Res. 2012;1:57doi: 10.4103/2277-9175.100175.
Aslani, A., & Rafiei, S. (2012). Design, formulation and evaluation of nicotine chewing gum. Advanced biomedical research, 157. https://doi.org/10.4103/2277-9175.100175
Aslani, Abolfazl, and Rafiei, Sahar. "Design, formulation and evaluation of nicotine chewing gum." Advanced biomedical research vol. 1 (2012): 57. doi: https://doi.org/10.4103/2277-9175.100175
Aslani A, Rafiei S. Design, formulation and evaluation of nicotine chewing gum. Adv Biomed Res. 2012;1:57. doi: 10.4103/2277-9175.100175. Epub 2012 Aug 28. PMID: 23326788; PMCID: PMC3544094.
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Aspartame and PKU.

Canadian family physician Medecin de famille canadien

McSherry JA.
PMID: 21286097
Can Fam Physician. 1982 May;28:846-79.

No abstract available.

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McSherry JA. Aspartame and PKU. Can Fam Physician. 1982;28:846-79
McSherry, J. A. (1982). Aspartame and PKU. Canadian family physician Medecin de famille canadien, 28846-79.
McSherry, J A. "Aspartame and PKU." Canadian family physician Medecin de famille canadien vol. 28 (1982): 846-79.
McSherry JA. Aspartame and PKU. Can Fam Physician. 1982 May;28:846-79. PMID: 21286097; PMCID: PMC2306431.
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Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function.

Mycotoxin research

Köhler H, Heller M, Erler W, Müller G, Rosner H, Gräfe U.
PMID: 23606156
Mycotoxin Res. 2002 Jun;18:169-72. doi: 10.1007/BF02946089.

The effect of practically relevant mycotoxin concentrations on functions of immune cells was studied in in vitro experiments. Porcine mononuclear cells were exposed to a crudeAspergillus-ochraceus toxin containing OTA, a HPLC fraction identical with OTC derived from the crude...

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Köhler H, Heller M, Erler W, et al. Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function. Mycotoxin Res. 2002;18:169-72doi: 10.1007/BF02946089.
Köhler, H., Heller, M., Erler, W., Müller, G., Rosner, H., & Gräfe, U. (2002). Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function. Mycotoxin research, 18169-72. https://doi.org/10.1007/BF02946089
Köhler, H, et al. "Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function." Mycotoxin research vol. 18 (2002): 169-72. doi: https://doi.org/10.1007/BF02946089
Köhler H, Heller M, Erler W, Müller G, Rosner H, Gräfe U. Effect of ochratoxin A and ochratoxin C on the monocyte and lymphocyte function. Mycotoxin Res. 2002 Jun;18:169-72. doi: 10.1007/BF02946089. PMID: 23606156.
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Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials.

Advances in nutrition (Bethesda, Md.)

Ruiz-Ojeda FJ, Plaza-Díaz J, Sáez-Lara MJ, Gil A.
PMID: 30721958
Adv Nutr. 2019 Jan 01;10:S31-S48. doi: 10.1093/advances/nmy037.

The consumption of sugar-free foods is growing because of their low-calorie content and the health concerns about products with high sugar content. Sweeteners that are frequently several hundred thousand times sweeter than sucrose are being consumed as sugar substitutes....

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Ruiz-Ojeda FJ, Plaza-Díaz J, Sáez-Lara MJ, et al. Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials. Adv Nutr. 2019;10:S31-S48doi: 10.1093/advances/nmy037.
Ruiz-Ojeda, F. J., Plaza-Díaz, J., Sáez-Lara, M. J., & Gil, A. (2019). Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials. Advances in nutrition (Bethesda, Md.), 10S31-S48. https://doi.org/10.1093/advances/nmy037
Ruiz-Ojeda, Francisco Javier, et al. "Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials." Advances in nutrition (Bethesda, Md.) vol. 10 (2019): S31-S48. doi: https://doi.org/10.1093/advances/nmy037
Ruiz-Ojeda FJ, Plaza-Díaz J, Sáez-Lara MJ, Gil A. Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials. Adv Nutr. 2019 Jan 01;10:S31-S48. doi: 10.1093/advances/nmy037. PMID: 30721958; PMCID: PMC6363527.
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N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress.

Free radical biology & medicine

Finamor I, Pavanato MA, Pês T, Ourique G, Saccol E, Schiefelbein S, Llesuy S, Partata W.
PMID: 26461335
Free Radic Biol Med. 2014 Oct;75:S30. doi: 10.1016/j.freeradbiomed.2014.10.759. Epub 2014 Dec 10.

Long-term intake of aspartame at the acceptable daily ingestion dose causes oxidative stress in the rat kidney through the dysregulation of glutathione homeostasis. N-acetylcysteine (NAC) provides the cystein required for the production of GSH, being effective in treating disorders...

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Finamor I, Pavanato MA, Pês T, et al. N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress. Free Radic Biol Med. 2014;75:S30doi: 10.1016/j.freeradbiomed.2014.10.759.
Finamor, I., Pavanato, M. A., Pês, T., Ourique, G., Saccol, E., Schiefelbein, S., Llesuy, S., & Partata, W. (2014). N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress. Free radical biology & medicine, 75S30. https://doi.org/10.1016/j.freeradbiomed.2014.10.759
Finamor, Isabela, et al. "N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress." Free radical biology & medicine vol. 75 (2014): S30. doi: https://doi.org/10.1016/j.freeradbiomed.2014.10.759
Finamor I, Pavanato MA, Pês T, Ourique G, Saccol E, Schiefelbein S, Llesuy S, Partata W. N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress. Free Radic Biol Med. 2014 Oct;75:S30. doi: 10.1016/j.freeradbiomed.2014.10.759. Epub 2014 Dec 10. PMID: 26461335.
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Organic-Inorganic Nanohybrid Electrochemical Sensors from Multi-Walled Carbon Nanotubes Decorated with Zinc Oxide Nanoparticles and In-Situ Wrapped with Poly(2-methacryloyloxyethyl ferrocenecarboxylate) for Detection of the Content of Food Additives.

Nanomaterials (Basel, Switzerland)

Xu JW, Cui ZM, Liu ZQ, Xu F, Chen YS, Luo YL.
PMID: 31569770
Nanomaterials (Basel). 2019 Sep 27;9(10). doi: 10.3390/nano9101388.

An electrochemical sensor for detection of the content of aspartame was developed by modifying a glassy carbon electrode (GCE) with multi-walled carbon nanotubes decorated with zinc oxide nanoparticles and in-situ wrapped with poly(2-methacryloyloxyethyl ferrocenecarboxylate) (MWCNTs@ZnO/PMAEFc). MWCNTs@ZnO/PMAEFc nanohybrids were prepared...

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Xu JW, Cui ZM, Liu ZQ, et al. Organic-Inorganic Nanohybrid Electrochemical Sensors from Multi-Walled Carbon Nanotubes Decorated with Zinc Oxide Nanoparticles and In-Situ Wrapped with Poly(2-methacryloyloxyethyl ferrocenecarboxylate) for Detection of the Content of Food Additives. Nanomaterials (Basel). 2019;9(10)doi: 10.3390/nano9101388.
Xu, J. W., Cui, Z. M., Liu, Z. Q., Xu, F., Chen, Y. S., & Luo, Y. L. (2019). Organic-Inorganic Nanohybrid Electrochemical Sensors from Multi-Walled Carbon Nanotubes Decorated with Zinc Oxide Nanoparticles and In-Situ Wrapped with Poly(2-methacryloyloxyethyl ferrocenecarboxylate) for Detection of the Content of Food Additives. Nanomaterials (Basel, Switzerland), 9(10), . https://doi.org/10.3390/nano9101388
Xu, Jing-Wen, et al. "Organic-Inorganic Nanohybrid Electrochemical Sensors from Multi-Walled Carbon Nanotubes Decorated with Zinc Oxide Nanoparticles and In-Situ Wrapped with Poly(2-methacryloyloxyethyl ferrocenecarboxylate) for Detection of the Content of Food Additives." Nanomaterials (Basel, Switzerland) vol. 9,10 (2019). doi: https://doi.org/10.3390/nano9101388
Xu JW, Cui ZM, Liu ZQ, Xu F, Chen YS, Luo YL. Organic-Inorganic Nanohybrid Electrochemical Sensors from Multi-Walled Carbon Nanotubes Decorated with Zinc Oxide Nanoparticles and In-Situ Wrapped with Poly(2-methacryloyloxyethyl ferrocenecarboxylate) for Detection of the Content of Food Additives. Nanomaterials (Basel). 2019 Sep 27;9(10). doi: 10.3390/nano9101388. PMID: 31569770; PMCID: PMC6835561.
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Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve.

Journal of microscopy and ultrastructure

Okasha EF.
PMID: 30023225
J Microsc Ultrastruct. 2016 Oct-Dec;4(4):175-183. doi: 10.1016/j.jmau.2016.02.001. Epub 2016 Feb 15.

Aspartame is the most widely used artificial sweetener worldwide. There is much controversy about the effect of aspartame on different cells in the body. The aim of this study was to evaluate the effect of aspartame on the structure...

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Okasha EF. Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve. J Microsc Ultrastruct. 2016;4(4):175-183doi: 10.1016/j.jmau.2016.02.001.
Okasha, E. F. (2016). Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve. Journal of microscopy and ultrastructure, 4(4), 175-183. https://doi.org/10.1016/j.jmau.2016.02.001
Okasha, Ebtsam F. "Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve." Journal of microscopy and ultrastructure vol. 4,4 (2016): 175-183. doi: https://doi.org/10.1016/j.jmau.2016.02.001
Okasha EF. Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve. J Microsc Ultrastruct. 2016 Oct-Dec;4(4):175-183. doi: 10.1016/j.jmau.2016.02.001. Epub 2016 Feb 15. PMID: 30023225; PMCID: PMC6014252.
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Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis.

Journal of agricultural and food chemistry

Li X, Dong G, Han G, Du L, Li M.
PMID: 34874711
J Agric Food Chem. 2021 Dec 07; doi: 10.1021/acs.jafc.1c06077. Epub 2021 Dec 07.

Artificial sweeteners (ASs) are extensively used as food additives in drinks and beverages to lower calorie intake and prevent lifestyle diseases such as obesity. Although clinical and epidemiological data revealed the link between the chronic overconsumption of ASs and...

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Li X, Dong G, Han G, et al. Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis. J Agric Food Chem. 2021;doi: 10.1021/acs.jafc.1c06077.
Li, X., Dong, G., Han, G., Du, L., & Li, M. (2021). Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis. Journal of agricultural and food chemistry, . https://doi.org/10.1021/acs.jafc.1c06077
Li, Xiang, et al. "Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis." Journal of agricultural and food chemistry vol. (2021). doi: https://doi.org/10.1021/acs.jafc.1c06077
Li X, Dong G, Han G, Du L, Li M. Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis. J Agric Food Chem. 2021 Dec 07; doi: 10.1021/acs.jafc.1c06077. Epub 2021 Dec 07. PMID: 34874711.
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Comparison of aspartame- and sugar-sweetened soft drinks on postprandial metabolism.

Nutrition and health

Pearson RC, Green ES, Olenick AA, Jenkins NT.
PMID: 34841959
Nutr Health. 2021 Nov 29;2601060211057415. doi: 10.1177/02601060211057415. Epub 2021 Nov 29.

No abstract available.

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Pearson RC, Green ES, Olenick AA, et al. Comparison of aspartame- and sugar-sweetened soft drinks on postprandial metabolism. Nutr Health. 2021;2601060211057415doi: 10.1177/02601060211057415.
Pearson, R. C., Green, E. S., Olenick, A. A., & Jenkins, N. T. (2021). Comparison of aspartame- and sugar-sweetened soft drinks on postprandial metabolism. Nutrition and health, 2601060211057415. https://doi.org/10.1177/02601060211057415
Pearson, Regis C, et al. "Comparison of aspartame- and sugar-sweetened soft drinks on postprandial metabolism." Nutrition and health vol. (2021): 2601060211057415. doi: https://doi.org/10.1177/02601060211057415
Pearson RC, Green ES, Olenick AA, Jenkins NT. Comparison of aspartame- and sugar-sweetened soft drinks on postprandial metabolism. Nutr Health. 2021 Nov 29;2601060211057415. doi: 10.1177/02601060211057415. Epub 2021 Nov 29. PMID: 34841959.
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Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model.

Journal of dentistry

Augustinho do Nascimento C, Kim RR, Ferrari CR, de Souza BM, Braga AS, Magalhães AC.
PMID: 34653536
J Dent. 2021 Dec;115:103835. doi: 10.1016/j.jdent.2021.103835. Epub 2021 Oct 12.

OBJECTIVE: This study compared the effect of commercial and pure sweetener containing stevia to that of aspartame, to sucrose and xylitol on the development of dental caries.METHODS: 228 bovine enamel and root dentin were exposed to microcosm biofilm model...

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Augustinho do Nascimento C, Kim RR, Ferrari CR, et al. Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model. J Dent. 2021;115:103835doi: 10.1016/j.jdent.2021.103835.
Augustinho do Nascimento, C., Kim, R. R., Ferrari, C. R., de Souza, B. M., Braga, A. S., & Magalhães, A. C. (2021). Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model. Journal of dentistry, 115103835. https://doi.org/10.1016/j.jdent.2021.103835
Augustinho do Nascimento, Caren, et al. "Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model." Journal of dentistry vol. 115 (2021): 103835. doi: https://doi.org/10.1016/j.jdent.2021.103835
Augustinho do Nascimento C, Kim RR, Ferrari CR, de Souza BM, Braga AS, Magalhães AC. Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model. J Dent. 2021 Dec;115:103835. doi: 10.1016/j.jdent.2021.103835. Epub 2021 Oct 12. PMID: 34653536.
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Showing 13 to 24 of 143 entries