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Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Gendy AM, Elnagar MR, Allam MM, Mousa MR, Khodir AE, El-Haddad AE, Elnahas OS, Fayez SM, El-Mancy SS.
PMID: 34489150
Biomed Pharmacother. 2022 Jan;145:112122. doi: 10.1016/j.biopha.2021.112122. Epub 2021 Sep 04.

OBJECTIVE: Berberine (BBR) is a known alkaloid that has verified its protective effects against ischemia/reperfusion (I/RN) lesion in multiple organs but its poor oral bioavailability limited its use. Despite the previous works, its possible impact on the warm hepatic...

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Gendy AM, Elnagar MR, Allam MM, et al. Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy. Biomed Pharmacother. 2021;145:112122doi: 10.1016/j.biopha.2021.112122.
Gendy, A. M., Elnagar, M. R., Allam, M. M., Mousa, M. R., Khodir, A. E., El-Haddad, A. E., Elnahas, O. S., Fayez, S. M., & El-Mancy, S. S. (2022). Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 145112122. https://doi.org/10.1016/j.biopha.2021.112122
Gendy, Abdallah M, et al. "Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 145 (2022): 112122. doi: https://doi.org/10.1016/j.biopha.2021.112122
Gendy AM, Elnagar MR, Allam MM, Mousa MR, Khodir AE, El-Haddad AE, Elnahas OS, Fayez SM, El-Mancy SS. Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy. Biomed Pharmacother. 2022 Jan;145:112122. doi: 10.1016/j.biopha.2021.112122. Epub 2021 Sep 04. PMID: 34489150.
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Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice.

Bioorganic & medicinal chemistry

Yang L, Yu S, Yang Y, Wu H, Zhang X, Lei Y, Lei Z.
PMID: 34979291
Bioorg Med Chem. 2021 Dec 30;55:116598. doi: 10.1016/j.bmc.2021.116598. Epub 2021 Dec 30.

Liver injury mediated by endoplasmic reticulum (ER) stress can cause many kinds of liver diseases including hepatic glucose and lipid metabolic disorders, and long term liver injury would lead to cirrhosis and hepatic cancer. Therefore, effective drugs for treating...

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Yang L, Yu S, Yang Y, et al. Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice. Bioorg Med Chem. 2021;55:116598doi: 10.1016/j.bmc.2021.116598.
Yang, L., Yu, S., Yang, Y., Wu, H., Zhang, X., Lei, Y., & Lei, Z. (2021). Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice. Bioorganic & medicinal chemistry, 55116598. https://doi.org/10.1016/j.bmc.2021.116598
Yang, Lanxiang, et al. "Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice." Bioorganic & medicinal chemistry vol. 55 (2021): 116598. doi: https://doi.org/10.1016/j.bmc.2021.116598
Yang L, Yu S, Yang Y, Wu H, Zhang X, Lei Y, Lei Z. Berberine improves liver injury induced glucose and lipid metabolic disorders via alleviating ER stress of hepatocytes and modulating gut microbiota in mice. Bioorg Med Chem. 2021 Dec 30;55:116598. doi: 10.1016/j.bmc.2021.116598. Epub 2021 Dec 30. PMID: 34979291.
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Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice.

Naunyn-Schmiedeberg's archives of pharmacology

Mombeini MA, Kalantar H, Sadeghi E, Goudarzi M, Khalili H, Kalantar M.
PMID: 34994821
Naunyn Schmiedebergs Arch Pharmacol. 2022 Feb;395(2):187-194. doi: 10.1007/s00210-021-02182-3. Epub 2022 Jan 07.

PURPOSE: Cyclophosphamide is an alkylating agent with nephrotoxicity that constrains its clinical application. Berberine is an isoquinoline derivative alkaloid with biological functions like antioxidant and anti-inflammatory. The current research intended to examine the nephroprotective impacts of berberine against cyclophosphamide-stimulated...

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Mombeini MA, Kalantar H, Sadeghi E, et al. Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice. Naunyn Schmiedebergs Arch Pharmacol. 2022;395(2):187-194doi: 10.1007/s00210-021-02182-3.
Mombeini, M. A., Kalantar, H., Sadeghi, E., Goudarzi, M., Khalili, H., & Kalantar, M. (2022). Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice. Naunyn-Schmiedeberg's archives of pharmacology, 395(2), 187-194. https://doi.org/10.1007/s00210-021-02182-3
Mombeini, Mohammad Amin, et al. "Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice." Naunyn-Schmiedeberg's archives of pharmacology vol. 395,2 (2022): 187-194. doi: https://doi.org/10.1007/s00210-021-02182-3
Mombeini MA, Kalantar H, Sadeghi E, Goudarzi M, Khalili H, Kalantar M. Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice. Naunyn Schmiedebergs Arch Pharmacol. 2022 Feb;395(2):187-194. doi: 10.1007/s00210-021-02182-3. Epub 2022 Jan 07. PMID: 34994821.
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Berberine as a Potential Anticancer Agent: A Comprehensive Review.

Molecules (Basel, Switzerland)

Rauf A, Abu-Izneid T, Khalil AA, Imran M, Shah ZA, Emran TB, Mitra S, Khan Z, Alhumaydhi FA, Aljohani ASM, Khan I, Rahman MM, Jeandet P, Gondal TA.
PMID: 34885950
Molecules. 2021 Dec 04;26(23). doi: 10.3390/molecules26237368.

Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of...

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Rauf A, Abu-Izneid T, Khalil AA, et al. Berberine as a Potential Anticancer Agent: A Comprehensive Review. Molecules. 2021;26(23)doi: 10.3390/molecules26237368.
Rauf, A., Abu-Izneid, T., Khalil, A. A., Imran, M., Shah, Z. A., Emran, T. B., Mitra, S., Khan, Z., Alhumaydhi, F. A., Aljohani, A. S. M., Khan, I., Rahman, M. M., Jeandet, P., & Gondal, T. A. (2021). Berberine as a Potential Anticancer Agent: A Comprehensive Review. Molecules (Basel, Switzerland), 26(23), . https://doi.org/10.3390/molecules26237368
Rauf, Abdur, et al. "Berberine as a Potential Anticancer Agent: A Comprehensive Review." Molecules (Basel, Switzerland) vol. 26,23 (2021). doi: https://doi.org/10.3390/molecules26237368
Rauf A, Abu-Izneid T, Khalil AA, Imran M, Shah ZA, Emran TB, Mitra S, Khan Z, Alhumaydhi FA, Aljohani ASM, Khan I, Rahman MM, Jeandet P, Gondal TA. Berberine as a Potential Anticancer Agent: A Comprehensive Review. Molecules. 2021 Dec 04;26(23). doi: 10.3390/molecules26237368. PMID: 34885950; PMCID: PMC8658774.
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Showing 1381 to 1384 of 1384 entries