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Photonic nanojet array for fast detection of single nanoparticles in a flow.

Nano letters

Yang H, Cornaglia M, Gijs MA.
PMID: 25664916
Nano Lett. 2015 Mar 11;15(3):1730-5. doi: 10.1021/nl5044067. Epub 2015 Feb 18.

We detect by optical microscopy Au and fluorescent nanoparticles (NPs) during their motion in water-based medium, using an array of dielectric microspheres that are patterned in a microwell array template. The microspheres act as lenses focusing the light originating...

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Yang H, Cornaglia M, Gijs MA. Photonic nanojet array for fast detection of single nanoparticles in a flow. Nano Lett. 2015;15(3):1730-5doi: 10.1021/nl5044067.
Yang, H., Cornaglia, M., & Gijs, M. A. (2015). Photonic nanojet array for fast detection of single nanoparticles in a flow. Nano letters, 15(3), 1730-5. https://doi.org/10.1021/nl5044067
Yang, Hui, et al. "Photonic nanojet array for fast detection of single nanoparticles in a flow." Nano letters vol. 15,3 (2015): 1730-5. doi: https://doi.org/10.1021/nl5044067
Yang H, Cornaglia M, Gijs MA. Photonic nanojet array for fast detection of single nanoparticles in a flow. Nano Lett. 2015 Mar 11;15(3):1730-5. doi: 10.1021/nl5044067. Epub 2015 Feb 18. PMID: 25664916.
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β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway.

Biomolecules & therapeutics

Yu HY, Kim SO, Jin CY, Kim GY, Kim WJ, Yoo YH, Choi YH.
PMID: 25009698
Biomol Ther (Seoul). 2014 May;22(3):184-92. doi: 10.4062/biomolther.2014.026.

β-lapachone is a naturally occurring quinone that selectively induces apoptotic cell death in a variety of human cancer cells in vitro and in vivo; however, its mechanism of action needs to be further elaborated. In this study, we investigated...

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Yu HY, Kim SO, Jin CY, et al. β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway. Biomol Ther (Seoul). 2014;22(3):184-92doi: 10.4062/biomolther.2014.026.
Yu, H. Y., Kim, S. O., Jin, C. Y., Kim, G. Y., Kim, W. J., Yoo, Y. H., & Choi, Y. H. (2014). β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway. Biomolecules & therapeutics, 22(3), 184-92. https://doi.org/10.4062/biomolther.2014.026
Yu, Hai Yang, et al. "β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway." Biomolecules & therapeutics vol. 22,3 (2014): 184-92. doi: https://doi.org/10.4062/biomolther.2014.026
Yu HY, Kim SO, Jin CY, Kim GY, Kim WJ, Yoo YH, Choi YH. β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway. Biomol Ther (Seoul). 2014 May;22(3):184-92. doi: 10.4062/biomolther.2014.026. PMID: 25009698; PMCID: PMC4060078.
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Involvement of Transglutaminase-2 in α-MSH-Induced Melanogenesis in SK-MEL-2 Human Melanoma Cells.

Biomolecules & therapeutics

Kim HJ, Lee HJ, Park MK, Gang KJ, Byun HJ, Park JH, Kim MK, Kim SY, Lee CH.
PMID: 25009701
Biomol Ther (Seoul). 2014 May;22(3):207-12. doi: 10.4062/biomolther.2014.031.

Skin hyperpigmentation is one of the most common skin disorders caused by abnormal melanogenesis. The mechanism and key factors at play are not fully understood. Previous reports have indicated that cystamine (CTM) inhibits melanin synthesis, though its molecular mechanism...

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Kim HJ, Lee HJ, Park MK, et al. Involvement of Transglutaminase-2 in α-MSH-Induced Melanogenesis in SK-MEL-2 Human Melanoma Cells. Biomol Ther (Seoul). 2014;22(3):207-12doi: 10.4062/biomolther.2014.031.
Kim, H. J., Lee, H. J., Park, M. K., Gang, K. J., Byun, H. J., Park, J. H., Kim, M. K., Kim, S. Y., & Lee, C. H. (2014). Involvement of Transglutaminase-2 in α-MSH-Induced Melanogenesis in SK-MEL-2 Human Melanoma Cells. Biomolecules & therapeutics, 22(3), 207-12. https://doi.org/10.4062/biomolther.2014.031
Kim, Hyun Ji, et al. "Involvement of Transglutaminase-2 in α-MSH-Induced Melanogenesis in SK-MEL-2 Human Melanoma Cells." Biomolecules & therapeutics vol. 22,3 (2014): 207-12. doi: https://doi.org/10.4062/biomolther.2014.031
Kim HJ, Lee HJ, Park MK, Gang KJ, Byun HJ, Park JH, Kim MK, Kim SY, Lee CH. Involvement of Transglutaminase-2 in α-MSH-Induced Melanogenesis in SK-MEL-2 Human Melanoma Cells. Biomol Ther (Seoul). 2014 May;22(3):207-12. doi: 10.4062/biomolther.2014.031. PMID: 25009701; PMCID: PMC4060083.
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Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol.

Biomolecules & therapeutics

Jung YY, Lee YJ, Choi DY, Hong JT.
PMID: 25009704
Biomol Ther (Seoul). 2014 May;22(3):232-8. doi: 10.4062/biomolther.2014.030.

Alzheimer's disease (AD) is the most common neurodegenerative disease without known ways to cure. A key neuropathologic manifestation of the disease is extracellular deposition of beta-amyloid peptide (Aβ). Specific mechanisms underlying the development of the disease have not yet...

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Jung YY, Lee YJ, Choi DY, et al. Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol. Biomol Ther (Seoul). 2014;22(3):232-8doi: 10.4062/biomolther.2014.030.
Jung, Y. Y., Lee, Y. J., Choi, D. Y., & Hong, J. T. (2014). Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol. Biomolecules & therapeutics, 22(3), 232-8. https://doi.org/10.4062/biomolther.2014.030
Jung, Yu-Yeon, et al. "Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol." Biomolecules & therapeutics vol. 22,3 (2014): 232-8. doi: https://doi.org/10.4062/biomolther.2014.030
Jung YY, Lee YJ, Choi DY, Hong JT. Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol. Biomol Ther (Seoul). 2014 May;22(3):232-8. doi: 10.4062/biomolther.2014.030. PMID: 25009704; PMCID: PMC4060074.
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Ion aggregation in high salt solutions. V. Graph entropy analyses of ion aggregate structure and water hydrogen bonding network.

The Journal of chemical physics

Choi JH, Cho M.
PMID: 27250298
J Chem Phys. 2016 May 28;144(20):204126. doi: 10.1063/1.4952648.

Dissolved ions in water tend to form polydisperse ion aggregates such as ion pairs, relatively compact ion clusters, and even spatially extended ion networks with increasing salt concentration. Combining molecular dynamics simulation and graph theoretical analysis methods, we recently...

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Choi JH, Cho M. Ion aggregation in high salt solutions. V. Graph entropy analyses of ion aggregate structure and water hydrogen bonding network. J Chem Phys. 2016;144(20):204126doi: 10.1063/1.4952648.
Choi, J. H., & Cho, M. (2016). Ion aggregation in high salt solutions. V. Graph entropy analyses of ion aggregate structure and water hydrogen bonding network. The Journal of chemical physics, 144(20), 204126. https://doi.org/10.1063/1.4952648
Choi, Jun-Ho, and Cho, Minhaeng. "Ion aggregation in high salt solutions. V. Graph entropy analyses of ion aggregate structure and water hydrogen bonding network." The Journal of chemical physics vol. 144,20 (2016): 204126. doi: https://doi.org/10.1063/1.4952648
Choi JH, Cho M. Ion aggregation in high salt solutions. V. Graph entropy analyses of ion aggregate structure and water hydrogen bonding network. J Chem Phys. 2016 May 28;144(20):204126. doi: 10.1063/1.4952648. PMID: 27250298.
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Insulin as a Potent Stimulator of Akt, ERK and Inhibin-βE Signaling in Osteoblast-Like UMR-106 Cells.

Biomolecules & therapeutics

Ramalingam M, Kwon YD, Kim SJ.
PMID: 27302964
Biomol Ther (Seoul). 2016 Nov 01;24(6):589-594. doi: 10.4062/biomolther.2016.030.

Insulin is a peptide hormone of the endocrine pancreas and exerts a wide variety of physiological actions in insulin sensitive tissues, such as regulation of glucose homeostasis, cell growth, differentiation, learning and memory. However, the role of insulin in...

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Ramalingam M, Kwon YD, Kim SJ. Insulin as a Potent Stimulator of Akt, ERK and Inhibin-βE Signaling in Osteoblast-Like UMR-106 Cells. Biomol Ther (Seoul). 2016;24(6):589-594doi: 10.4062/biomolther.2016.030.
Ramalingam, M., Kwon, Y. D., & Kim, S. J. (2016). Insulin as a Potent Stimulator of Akt, ERK and Inhibin-βE Signaling in Osteoblast-Like UMR-106 Cells. Biomolecules & therapeutics, 24(6), 589-594. https://doi.org/10.4062/biomolther.2016.030
Ramalingam, Mahesh, et al. "Insulin as a Potent Stimulator of Akt, ERK and Inhibin-βE Signaling in Osteoblast-Like UMR-106 Cells." Biomolecules & therapeutics vol. 24,6 (2016): 589-594. doi: https://doi.org/10.4062/biomolther.2016.030
Ramalingam M, Kwon YD, Kim SJ. Insulin as a Potent Stimulator of Akt, ERK and Inhibin-βE Signaling in Osteoblast-Like UMR-106 Cells. Biomol Ther (Seoul). 2016 Nov 01;24(6):589-594. doi: 10.4062/biomolther.2016.030. PMID: 27302964; PMCID: PMC5098537.
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Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes.

Biomolecules & therapeutics

Park JS, Kim DK, Shin HD, Lee HJ, Jo HS, Jeong JH, Choi YL, Lee CJ, Hwang SC.
PMID: 26902085
Biomol Ther (Seoul). 2016 Mar 01;24(2):163-70. doi: 10.4062/biomolther.2015.217.

We examined whether apigenin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the knee joint of rat to evaluate the potential...

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Park JS, Kim DK, Shin HD, et al. Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes. Biomol Ther (Seoul). 2016;24(2):163-70doi: 10.4062/biomolther.2015.217.
Park, J. S., Kim, D. K., Shin, H. D., Lee, H. J., Jo, H. S., Jeong, J. H., Choi, Y. L., Lee, C. J., & Hwang, S. C. (2016). Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes. Biomolecules & therapeutics, 24(2), 163-70. https://doi.org/10.4062/biomolther.2015.217
Park, Jin Sung, et al. "Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes." Biomolecules & therapeutics vol. 24,2 (2016): 163-70. doi: https://doi.org/10.4062/biomolther.2015.217
Park JS, Kim DK, Shin HD, Lee HJ, Jo HS, Jeong JH, Choi YL, Lee CJ, Hwang SC. Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes. Biomol Ther (Seoul). 2016 Mar 01;24(2):163-70. doi: 10.4062/biomolther.2015.217. PMID: 26902085; PMCID: PMC4774497.
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Accuracy of the detection of binding events using 3D single particle tracking.

BMC biophysics

Carozza S, Culkin J, van Noort J.
PMID: 28344779
BMC Biophys. 2017 Mar 23;10:3. doi: 10.1186/s13628-017-0035-8. eCollection 2017.

BACKGROUND: Nanoparticles can be used as markers to track the position of biomolecules, such as single proteins, inside living cells. The activity of a protein can sometimes be inferred from changes in the mobility of the attached particle. Mean...

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Carozza S, Culkin J, van Noort J. Accuracy of the detection of binding events using 3D single particle tracking. BMC Biophys. 2017;10:3doi: 10.1186/s13628-017-0035-8.
Carozza, S., Culkin, J., & van Noort, J. (2017). Accuracy of the detection of binding events using 3D single particle tracking. BMC biophysics, 103. https://doi.org/10.1186/s13628-017-0035-8
Carozza, Sara, et al. "Accuracy of the detection of binding events using 3D single particle tracking." BMC biophysics vol. 10 (2017): 3. doi: https://doi.org/10.1186/s13628-017-0035-8
Carozza S, Culkin J, van Noort J. Accuracy of the detection of binding events using 3D single particle tracking. BMC Biophys. 2017 Mar 23;10:3. doi: 10.1186/s13628-017-0035-8. eCollection 2017. PMID: 28344779; PMCID: PMC5364544.
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Bioorthogonal Chemical Activation of Kinases in Living Systems.

ACS central science

Zhang G, Li J, Xie R, Fan X, Liu Y, Zheng S, Ge Y, Chen PR.
PMID: 27280167
ACS Cent Sci. 2016 May 25;2(5):325-31. doi: 10.1021/acscentsci.6b00024. Epub 2016 Apr 27.

Selective manipulation of protein kinases under living conditions is highly desirable yet extremely challenging, particularly in a gain-of-function fashion. Here we employ our recently developed bioorthogonal cleavage reaction as a general strategy for intracellular activation of individual kinases. Site-specific...

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Zhang G, Li J, Xie R, et al. Bioorthogonal Chemical Activation of Kinases in Living Systems. ACS Cent Sci. 2016;2(5):325-31doi: 10.1021/acscentsci.6b00024.
Zhang, G., Li, J., Xie, R., Fan, X., Liu, Y., Zheng, S., Ge, Y., & Chen, P. R. (2016). Bioorthogonal Chemical Activation of Kinases in Living Systems. ACS central science, 2(5), 325-31. https://doi.org/10.1021/acscentsci.6b00024
Zhang, Gong, et al. "Bioorthogonal Chemical Activation of Kinases in Living Systems." ACS central science vol. 2,5 (2016): 325-31. doi: https://doi.org/10.1021/acscentsci.6b00024
Zhang G, Li J, Xie R, Fan X, Liu Y, Zheng S, Ge Y, Chen PR. Bioorthogonal Chemical Activation of Kinases in Living Systems. ACS Cent Sci. 2016 May 25;2(5):325-31. doi: 10.1021/acscentsci.6b00024. Epub 2016 Apr 27. PMID: 27280167; PMCID: PMC4882735.
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Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells.

Biomolecules & therapeutics

Kim HJ, Kim J, Kang KS, Lee KT, Yang HO.
PMID: 25143804
Biomol Ther (Seoul). 2014 Jul;22(4):275-81. doi: 10.4062/biomolther.2014.068.

Autophagy is a series of catabolic process mediating the bulk degradation of intracellular proteins and organelles through formation of a double-membrane vesicle, known as an autophagosome, and fusing with lysosome. Autophagy plays an important role of death-survival decisions in...

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Kim HJ, Kim J, Kang KS, et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014;22(4):275-81doi: 10.4062/biomolther.2014.068.
Kim, H. J., Kim, J., Kang, K. S., Lee, K. T., & Yang, H. O. (2014). Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomolecules & therapeutics, 22(4), 275-81. https://doi.org/10.4062/biomolther.2014.068
Kim, Hee Ju, et al. "Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells." Biomolecules & therapeutics vol. 22,4 (2014): 275-81. doi: https://doi.org/10.4062/biomolther.2014.068
Kim HJ, Kim J, Kang KS, Lee KT, Yang HO. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells. Biomol Ther (Seoul). 2014 Jul;22(4):275-81. doi: 10.4062/biomolther.2014.068. PMID: 25143804; PMCID: PMC4131520.
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Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma.

Biomolecules & therapeutics

Ou Y, Li Q, Wang J, Li K, Zhou S.
PMID: 25143814
Biomol Ther (Seoul). 2014 Jul;22(4):341-6. doi: 10.4062/biomolther.2013.106.

Paeonol is a major phenolic micromolecular component of Moutan cortex Radicis, a traditional Chinese Medicine. It has shown antitumor effects in previous studies; however, the underlying mechanisms remain unknown. This study investigated the mechanism by giving treatments of placebo,...

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Ou Y, Li Q, Wang J, et al. Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma. Biomol Ther (Seoul). 2014;22(4):341-6doi: 10.4062/biomolther.2013.106.
Ou, Y., Li, Q., Wang, J., Li, K., & Zhou, S. (2014). Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma. Biomolecules & therapeutics, 22(4), 341-6. https://doi.org/10.4062/biomolther.2013.106
Ou, Yetao, et al. "Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma." Biomolecules & therapeutics vol. 22,4 (2014): 341-6. doi: https://doi.org/10.4062/biomolther.2013.106
Ou Y, Li Q, Wang J, Li K, Zhou S. Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma. Biomol Ther (Seoul). 2014 Jul;22(4):341-6. doi: 10.4062/biomolther.2013.106. PMID: 25143814; PMCID: PMC4131527.
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From Classical to Quantum and Back: A Hamiltonian Scheme for Adaptive Multiresolution Classical/Path-Integral Simulations.

Journal of chemical theory and computation

Kreis K, Tuckerman ME, Donadio D, Kremer K, Potestio R.
PMID: 27214610
J Chem Theory Comput. 2016 Jul 12;12(7):3030-9. doi: 10.1021/acs.jctc.6b00242. Epub 2016 Jun 08.

Quantum delocalization of atomic nuclei affects the physical properties of many hydrogen-rich liquids and biological systems even at room temperature. In computer simulations, quantum nuclei can be modeled via the path-integral formulation of quantum statistical mechanics, which implies a...

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Kreis K, Tuckerman ME, Donadio D, et al. From Classical to Quantum and Back: A Hamiltonian Scheme for Adaptive Multiresolution Classical/Path-Integral Simulations. J Chem Theory Comput. 2016;12(7):3030-9doi: 10.1021/acs.jctc.6b00242.
Kreis, K., Tuckerman, M. E., Donadio, D., Kremer, K., & Potestio, R. (2016). From Classical to Quantum and Back: A Hamiltonian Scheme for Adaptive Multiresolution Classical/Path-Integral Simulations. Journal of chemical theory and computation, 12(7), 3030-9. https://doi.org/10.1021/acs.jctc.6b00242
Kreis, Karsten, et al. "From Classical to Quantum and Back: A Hamiltonian Scheme for Adaptive Multiresolution Classical/Path-Integral Simulations." Journal of chemical theory and computation vol. 12,7 (2016): 3030-9. doi: https://doi.org/10.1021/acs.jctc.6b00242
Kreis K, Tuckerman ME, Donadio D, Kremer K, Potestio R. From Classical to Quantum and Back: A Hamiltonian Scheme for Adaptive Multiresolution Classical/Path-Integral Simulations. J Chem Theory Comput. 2016 Jul 12;12(7):3030-9. doi: 10.1021/acs.jctc.6b00242. Epub 2016 Jun 08. PMID: 27214610.
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Showing 13 to 24 of 8292 entries