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Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life.

Frontiers in pharmacology

Nifli AP, Tsolaki M, Tournoy J, Ide K.
PMID: 33584301
Front Pharmacol. 2021 Jan 29;11:618344. doi: 10.3389/fphar.2020.618344. eCollection 2020.

No abstract available.

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Nifli AP, Tsolaki M, Tournoy J, et al. Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life. Front Pharmacol. 2021;11:618344doi: 10.3389/fphar.2020.618344.
Nifli, A. P., Tsolaki, M., Tournoy, J., & Ide, K. (2020). Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life. Frontiers in pharmacology, 11618344. https://doi.org/10.3389/fphar.2020.618344
Nifli, Artemissia-Phoebe, et al. "Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life." Frontiers in pharmacology vol. 11 (2020): 618344. doi: https://doi.org/10.3389/fphar.2020.618344
Nifli AP, Tsolaki M, Tournoy J, Ide K. Editorial: Cognitive Impairment: Therapy Momentum in the Continuum of Life. Front Pharmacol. 2021 Jan 29;11:618344. doi: 10.3389/fphar.2020.618344. eCollection 2020. PMID: 33584301; PMCID: PMC7878524.
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Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review.

Current Alzheimer research

Musaeus CS, Nilsson C, Cooper C, Kramberger MG, Verdelho A, Stefanova E, Religa D, Waldemar G, Frederiksen KS.
PMID: 34825872
Curr Alzheimer Res. 2021;18(9):689-694. doi: 10.2174/1567205018666211126121529.

BACKGROUND: Patients with dementia have an increased risk of developing epilepsy, especially in patients with vascular dementia and Alzheimer's disease. In selecting the optimal anti- epileptic drug (AED), the possible side effects such as drowsiness and worsening of cognitive...

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Musaeus CS, Nilsson C, Cooper C, et al. Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review. Curr Alzheimer Res. 2021;18(9):689-694doi: 10.2174/1567205018666211126121529.
Musaeus, C. S., Nilsson, C., Cooper, C., Kramberger, M. G., Verdelho, A., Stefanova, E., Religa, D., Waldemar, G., & Frederiksen, K. S. (2021). Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review. Current Alzheimer research, 18(9), 689-694. https://doi.org/10.2174/1567205018666211126121529
Musaeus, Christian S, et al. "Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review." Current Alzheimer research vol. 18,9 (2021): 689-694. doi: https://doi.org/10.2174/1567205018666211126121529
Musaeus CS, Nilsson C, Cooper C, Kramberger MG, Verdelho A, Stefanova E, Religa D, Waldemar G, Frederiksen KS. Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review. Curr Alzheimer Res. 2021;18(9):689-694. doi: 10.2174/1567205018666211126121529. PMID: 34825872.
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Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative.

Alzheimer's & dementia (New York, N. Y.)

Stage E, Svaldi D, Sokolow S, Risacher SL, Marosi K, Rotter JI, Saykin AJ, Apostolova LG.
PMID: 35005201
Alzheimers Dement (N Y). 2021 Dec 31;7(1):e12168. doi: 10.1002/trc2.12168. eCollection 2021.

INTRODUCTION: Analyses of off-label use of acetylcholinesterase inhibitors (AChEIs) in mild cognitive impairment (MCI) has produced mixed results. Post hoc analyses of observational cohorts, such as the Alzheimer's Disease Neuroimaging Initiative (ADNI), have reported deleterious effects in AChEI-treated subjects...

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Stage E, Svaldi D, Sokolow S, et al. Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement (N Y). 2021;7(1):e12168doi: 10.1002/trc2.12168.
Stage, E., Svaldi, D., Sokolow, S., Risacher, S. L., Marosi, K., Rotter, J. I., Saykin, A. J., Apostolova, L. G. (2021). Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative. Alzheimer's & dementia (New York, N. Y.), 7(1), e12168. https://doi.org/10.1002/trc2.12168
Stage, Eddie, et al. "Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative." Alzheimer's & dementia (New York, N. Y.) vol. 7,1 (2021): e12168. doi: https://doi.org/10.1002/trc2.12168
Stage E, Svaldi D, Sokolow S, Risacher SL, Marosi K, Rotter JI, Saykin AJ, Apostolova LG. Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement (N Y). 2021 Dec 31;7(1):e12168. doi: 10.1002/trc2.12168. eCollection 2021. PMID: 35005201; PMCID: PMC8719350.
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Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.

Bioorganic & medicinal chemistry

Singh YP, Shankar G, Jahan S, Singh G, Kumar N, Barik A, Upadhyay P, Singh L, Kamble K, Singh GK, Tiwari S, Garg P, Gupta S, Modi G.
PMID: 34481338
Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385. Epub 2021 Aug 28.

In our earlier paper, we described ferulic acid (FA) template based novel series of multifunctional cholinesterase (ChE) inhibitors for the management of AD. This report has further extended the structure-activity relationship (SAR) studies of this series of molecules in...

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Singh YP, Shankar G, Jahan S, et al. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorg Med Chem. 2021;46:116385doi: 10.1016/j.bmc.2021.116385.
Singh, Y. P., Shankar, G., Jahan, S., Singh, G., Kumar, N., Barik, A., Upadhyay, P., Singh, L., Kamble, K., Singh, G. K., Tiwari, S., Garg, P., Gupta, S., & Modi, G. (2021). Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorganic & medicinal chemistry, 46116385. https://doi.org/10.1016/j.bmc.2021.116385
Singh, Yash Pal, et al. "Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease." Bioorganic & medicinal chemistry vol. 46 (2021): 116385. doi: https://doi.org/10.1016/j.bmc.2021.116385
Singh YP, Shankar G, Jahan S, Singh G, Kumar N, Barik A, Upadhyay P, Singh L, Kamble K, Singh GK, Tiwari S, Garg P, Gupta S, Modi G. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385. Epub 2021 Aug 28. PMID: 34481338.
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Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test.

Behavioural brain research

Fitzgerald PJ, Hale PJ, Ghimire A, Watson BO.
PMID: 33910028
Behav Brain Res. 2021 Jul 09;409:113323. doi: 10.1016/j.bbr.2021.113323. Epub 2021 Apr 25.

There is high clinical interest in improving the pharmacological treatment of individuals with Major Depressive Disorder (MDD). This neuropsychiatric disorder continues to cause significant morbidity and mortality worldwide, where existing pharmaceutical treatments such as selective serotonin reuptake inhibitors often...

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Fitzgerald PJ, Hale PJ, Ghimire A, et al. Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test. Behav Brain Res. 2021;409:113323doi: 10.1016/j.bbr.2021.113323.
Fitzgerald, P. J., Hale, P. J., Ghimire, A., & Watson, B. O. (2021). Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test. Behavioural brain research, 409113323. https://doi.org/10.1016/j.bbr.2021.113323
Fitzgerald, Paul J, et al. "Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test." Behavioural brain research vol. 409 (2021): 113323. doi: https://doi.org/10.1016/j.bbr.2021.113323
Fitzgerald PJ, Hale PJ, Ghimire A, Watson BO. Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test. Behav Brain Res. 2021 Jul 09;409:113323. doi: 10.1016/j.bbr.2021.113323. Epub 2021 Apr 25. PMID: 33910028; PMCID: PMC8493636.
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Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report.

The American journal of emergency medicine

Endo T, Amagasa S, Kashiura M, Kubota Y, Moriya T.
PMID: 34030906
Am J Emerg Med. 2021 Dec;50:811.e1-811.e2. doi: 10.1016/j.ajem.2021.05.027. Epub 2021 May 14.

A cholinergic crisiss is a state characterized by excess acetylcholine owing to the ingestion of cholinesterase inhibitors or cholinergic agonists. We report the first case of a cholinergic crisis after the ingestion of a carpronium chloride solution, a topical...

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Endo T, Amagasa S, Kashiura M, et al. Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report. Am J Emerg Med. 2021;50:811.e1-811.e2doi: 10.1016/j.ajem.2021.05.027.
Endo, T., Amagasa, S., Kashiura, M., Kubota, Y., & Moriya, T. (2021). Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report. The American journal of emergency medicine, 50811.e1-811.e2. https://doi.org/10.1016/j.ajem.2021.05.027
Endo, Takayuki, et al. "Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report." The American journal of emergency medicine vol. 50 (2021): 811.e1-811.e2. doi: https://doi.org/10.1016/j.ajem.2021.05.027
Endo T, Amagasa S, Kashiura M, Kubota Y, Moriya T. Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report. Am J Emerg Med. 2021 Dec;50:811.e1-811.e2. doi: 10.1016/j.ajem.2021.05.027. Epub 2021 May 14. PMID: 34030906.
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Cholinesterases in Tripartite Neuromuscular Synapse.

Frontiers in molecular neuroscience

Petrov KA, Proskurina SE, Krejci E.
PMID: 35002624
Front Mol Neurosci. 2021 Dec 23;14:811220. doi: 10.3389/fnmol.2021.811220. eCollection 2021.

The neuromuscular junction (NMJ) is a tripartite synapse in which not only presynaptic and post-synaptic cells participate in synaptic transmission, but also terminal Schwann cells (TSC). Acetylcholine (ACh) is the neurotransmitter that mediates the signal between the motor neuron...

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Petrov KA, Proskurina SE, Krejci E. Cholinesterases in Tripartite Neuromuscular Synapse. Front Mol Neurosci. 2021;14:811220doi: 10.3389/fnmol.2021.811220.
Petrov, K. A., Proskurina, S. E., & Krejci, E. (2021). Cholinesterases in Tripartite Neuromuscular Synapse. Frontiers in molecular neuroscience, 14811220. https://doi.org/10.3389/fnmol.2021.811220
Petrov, Konstantin A, et al. "Cholinesterases in Tripartite Neuromuscular Synapse." Frontiers in molecular neuroscience vol. 14 (2021): 811220. doi: https://doi.org/10.3389/fnmol.2021.811220
Petrov KA, Proskurina SE, Krejci E. Cholinesterases in Tripartite Neuromuscular Synapse. Front Mol Neurosci. 2021 Dec 23;14:811220. doi: 10.3389/fnmol.2021.811220. eCollection 2021. PMID: 35002624; PMCID: PMC8733319.
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Showing 409 to 415 of 415 entries