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Showing 325 to 335 of 335 entries
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Clinical and laboratory findings in patients with leukocyte adhesion deficiency type I: A multicenter study in Turkey.

Clinical and experimental immunology

Yaz I, Ozbek B, Bildik HN, Tan C, Oskay Halacli S, Soyak Aytekin E, Esenboga S, Cekic S, Kilic SS, Keskin O, van Leeuwen K, Roos D, Cagdas D, Tezcan I.
PMID: 34310689
Clin Exp Immunol. 2021 Oct;206(1):47-55. doi: 10.1111/cei.13645. Epub 2021 Aug 05.

Leukocyte adhesion deficiency type I is a rare primary immunodeficiency disorder characterized by mutations in the ITGB2 gene encoding CD18. We present clinical and immunological features of 15 patients with leukocyte adhesion deficiency type 1 (LAD-1). Targeted next-generation sequencing...

Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon.

Clinical and experimental immunology

Mbani Mpega Ntigui CN, Oyegue-Liabagui SL, Kouna LC, Imboumy KR, Tsafack Tegomo NP, Okouga AP, Ontoua S, Lekana-Douki JB.
PMID: 34363699
Clin Exp Immunol. 2021 Dec;206(3):395-409. doi: 10.1111/cei.13653. Epub 2021 Sep 06.

Cytokines are soluble mediators of the immune response, and their evolution influences the disease outcome. Gaining knowledge on cytokines has become important, as they can constitute biomarkers allowing the diagnosis of malaria and preventing severe forms of the disease....

Corrigendum.

Clinical and experimental immunology

[No authors listed]
PMID: 33890286
Clin Exp Immunol. 2021 May;204(2):283. doi: 10.1111/cei.13586. Epub 2021 Mar 25.

No abstract available.

Double-negative (DN) B cells: an under-recognized effector memory B cell subset in autoimmunity.

Clinical and experimental immunology

Li Y, Li Z, Hu F.
PMID: 33969476
Clin Exp Immunol. 2021 Aug;205(2):119-127. doi: 10.1111/cei.13615. Epub 2021 Jun 06.

Human B cells could be divided into four classical subsets based on CD27 and immunoglobulin (Ig)D expression. Distinct from the other three well-studied subsets, CD27

A.

Clinical and experimental immunology

Riff R, Naamani O, Mazar J, Haviv YS, Chaimovitz C, Douvdevani A.
PMID: 33894002
Clin Exp Immunol. 2021 Sep;205(3):278-287. doi: 10.1111/cei.13607. Epub 2021 Jun 02.

Adenosine is a potent modulator that has a tremendous effect on the immune system. Adenosine affects T cell activity, and is necessary in maintaining the T helper/regulatory T cell (T

Can cinnamon spice down autoimmune diseases?.

Journal of clinical & experimental immunology

Pahan S, Pahan K.
PMID: 33294884
J Clin Exp Immunol. 2020;5(6):252-258. doi: 10.33140/jcei.05.06.01. Epub 2020 Nov 23.

Autoimmune diseases are one of the dreadful group of human diseases that have always been of keen interest to researchers. Due to complex and broad-spectrum nature, scientists are not yet able to pinpoint the pathogenesis of and delineate effective...

Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis.

Clinical and experimental immunology

Isailovic N, Ceribelli A, Cincinelli G, Vecellio M, Guidelli G, Caprioli M, Luciano N, Motta F, Selmi C, De Santis M.
PMID: 33899926
Clin Exp Immunol. 2021 Aug;205(2):142-149. doi: 10.1111/cei.13609. Epub 2021 May 28.

Tofacitinib is an oral small molecule targeting the intracellular Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathways approved for the treatment of active rheumatoid arthritis (RA). We investigated the effects of tofacitinib on the response of RA lymphocytes...

Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis.

Clinical and experimental immunology

García-Laorden MI, Hoogendijk AJ, Wiewel MA, van Vught LA, Schultz MJ, Bovenschen N, de Vos AF, van der Poll T.
PMID: 33866542
Clin Exp Immunol. 2021 Aug;205(2):222-231. doi: 10.1111/cei.13601. Epub 2021 May 27.

Sepsis is a complex syndrome related to an infection-induced exaggerated inflammatory response, which is associated with a high mortality. Granzymes (Gzm) are proteases mainly found in cytotoxic lymphocytes that not only have a role in target cell death, but...

PMA induces the differentiation of monocytes into immunosuppressive MDSCs.

Clinical and experimental immunology

Wang H, Ji J, Zhuang Y, Zhou X, Zhao Y, Zhang X.
PMID: 34453319
Clin Exp Immunol. 2021 Nov;206(2):216-225. doi: 10.1111/cei.13657. Epub 2021 Sep 09.

The induction of immune tolerance without the use of immunosuppressive drugs is a crucial problem in organ transplantation. The use of myeloid-derived suppressor cells (MDSCs) as a cell-based adjuvant immunosuppressive therapy is a bright clinical prospect in organ transplantation....

Circulating regulatory T cells in adult-onset Still's disease: Focusing on their plasticity and stability.

Clinical and experimental immunology

Shimojima Y, Ichikawa T, Kishida D, Takamatsu R, Sekijima Y.
PMID: 34319596
Clin Exp Immunol. 2021 Nov;206(2):184-195. doi: 10.1111/cei.13648. Epub 2021 Aug 12.

We investigated the characteristics of regulatory T cells in adult-onset Still's disease (AOSD) with a focus on their plasticity, stability and relationship to disease severity. The proportion of circulating CD4

Reduced infiltration of regulatory T cells in tumours from mice fed daily with gamma-tocotrienol supplementation.

Clinical and experimental immunology

Subramaniam S, Anandha Rao JS, Ramdas P, Ng MH, Kannan Kutty M, Selvaduray KR, Radhakrishnan AK.
PMID: 34331768
Clin Exp Immunol. 2021 Nov;206(2):161-172. doi: 10.1111/cei.13650. Epub 2021 Aug 18.

Gamma-tocotrienol (γT3) is an analogue of vitamin E with beneficial effects on the immune system, including immune-modulatory properties. This study reports the immune-modulatory effects of daily supplementation of γT3 on host T helper (Th) and T regulatory cell (T

Showing 325 to 335 of 335 entries