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Showing 25 to 36 of 157 entries
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Lamotrigine augmentation of serotonin reuptake inhibitors in severe and long-term treatment-resistant obsessive-compulsive disorder.

Case reports in psychiatry

Arrojo-Romero M, Tajes Alonso M, de Leon J.
PMID: 23936714
Case Rep Psychiatry. 2013;2013:612459. doi: 10.1155/2013/612459. Epub 2013 Jul 14.

The treatment recommendations in obsessive-compulsive disorder (OCD) after lack of response to selective serotonin reuptake inhibitors (SSRIs) include augmentation with other drugs, particularly clomipramine, a more potent serotonin reuptake inhibitor (SRI), or antipsychotics. We present two cases of response...

The anxiety factor in depression.

Journal of psychopharmacology (Oxford, England)

Nutt D.
PMID: 22297237
J Psychopharmacol. 1995 Jan;9(2):185-9. doi: 10.1177/0269881195009002031.

Anxiety symptoms are commonly associated with depression, and contribute to a poorer patient prognosis. An increase in serotonergic function is implicated in the pathogenesis of anxiety and there is good evidence that the selective serotonin re-uptake inhibitors (SSRIs) may...

Influence of antidepressants on mitogen stimulation of human lymphocytes.

Toxicology in vitro : an international journal published in association with BIBRA

Mårtensson U, Nässberger L.
PMID: 20732195
Toxicol In Vitro. 1993 May;7(3):241-5. doi: 10.1016/0887-2333(93)90007-r.

Exposure to antidepressants inhibited mitogen stimulation of cultured human lymphocytes. The lowest concentration that cause total inhibition of mitogen (phytohaemagglutinin, PHA) stimulation (the minimum inhibitory concentration, MIC) was 20, 30, 40, 60 and 120 mumol/litre for fluoxetine, clomipramine, amitriptyline,...

Clomipramine, a better reference drug for panic/agoraphobia. I. Effectiveness comparison with imipramine.

Journal of psychopharmacology (Oxford, England)

Gentil V, Lotufo-Neto F, Andrade L, Cordás T, Bernik M, Ramos R, Maciel L, Miyakawa E, Gorenstein C.
PMID: 22290994
J Psychopharmacol. 1993 Jan;7(4):316-24. doi: 10.1177/026988119300700402.

An 8-week, double-blind, flexible-dose trial comparing low doses of clomipramine (mean=50 mg) with moderate doses of imipramine (mean=113.8 mg and propanteline (active placebo), was carried out in 60 out-patients with panic disorder with or without agoraphobia. Efficacy evaluation included...

Clomipramine induced mania.

Indian journal of psychiatry

Sathyanarayana V, Khanna S, Channabasavanna SM.
PMID: 21927502
Indian J Psychiatry. 1991 Jul;33(3):206-11.

A case of Obsessive Compulsive Disorder with no contributory or past history who developed delusional mania while on clomipramine is presented. The manic symptoms resolved after discontinuation of drug. The link between serotonin and mania is speculated upon. The...

Oxidation of tricyclic antidepressant drugs with chloramine-T in acidic solutions: kinetic, mechanistic and thermodynamic studies.

SpringerPlus

Sukhdev A, Puttaswamy P.
PMID: 23543721
Springerplus. 2013 Dec;2(1):30. doi: 10.1186/2193-1801-2-30. Epub 2013 Jan 30.

The kinetics of the oxidation of two tricyclic antidepressants (TCA) namely, imipramine (IMP) and clomipramine (CLM) with sodium N-chloro-p-toluenesulfonamide or chloramine-T (CAT) in HClO4 medium was studied at 300 K. The two reactions followed identical kinetics with a first-order...

High dose methylphenidate treatment in adult attention deficit hyperactivity disorder: a case report.

Journal of medical case reports

Liebrenz M, Hof D, Buadze A, Stohler R, Eich D.
PMID: 22583957
J Med Case Rep. 2012 May 14;6:125. doi: 10.1186/1752-1947-6-125.

INTRODUCTION: Stimulant medication improves hyperactivity, inattention, and impulsivity in both pediatric and adult populations with Attention Deficit Hyperactivity Disorder (ADHD). However, data regarding the optimal dosage in adults is still limited.CASE PRESENTATION: We report the case of a 38-year-old...

Intravenous lipid emulsion therapy for acute clomipramine intoxication in rats.

Acute medicine & surgery

Tsuji T, Hattori Y, Komori K, Yoshida Y, Banno R, Kohno T.
PMID: 29988692
Acute Med Surg. 2018 May 17;5(3):272-277. doi: 10.1002/ams2.344. eCollection 2018 Jul.

AIM: In this study, to assess the utility of lipid emulsion (ILE) therapy as a treatment option for overdoses of lipophilic drugs, we examined the detoxification effect of ILE therapy in rats that were administered overdoses of the tricyclic...

Beneficial Effect of Phenytoin and Carbamazepine on .

Frontiers in pharmacology

Bachetti T, Zanni ED, Adamo A, Rosamilia F, Sechi MM, Solla P, Bozzo M, Ceccherini I, Sechi G.
PMID: 34950024
Front Pharmacol. 2021 Dec 07;12:723218. doi: 10.3389/fphar.2021.723218. eCollection 2021.

Alexander's disease (AxD) is a rare, usually relentlessly progressive disorder of astroglial cells in the central nervous system related to mutations in the gene encoding the type III intermediate filament protein, glial fibrillary acidic protein (GFAP). The pathophysiology of...

Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Maski K, Trotti LM, Kotagal S, Robert Auger R, Swick TJ, Rowley JA, Hashmi SD, Watson NF.
PMID: 34743790
J Clin Sleep Med. 2021 Sep 01;17(9):1895-1945. doi: 10.5664/jcsm.9326.

INTRODUCTION: This systematic review provides supporting evidence for the accompanying clinical practice guideline on the treatment of central disorders of hypersomnolence in adults and children. The review focuses on prescription medications with U.S. Food & Drug Administration approval and...

Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant.

Frontiers in psychiatry

Vento AE, de Persis S, De Filippis S, Schifano F, Napoletano F, Corkery JM, Kotzalidis GD.
PMID: 33868054
Front Psychiatry. 2021 Mar 31;12:640218. doi: 10.3389/fpsyt.2021.640218. eCollection 2021.

Kratom or

Green synthesis and characterization of Solanum xanthocarpum capped silver nanoparticles and its antimicrobial effect on multidrug-resistant bacterial (MDR) isolates.

Chemical biology & drug design

Pungle R, Nile SH, Kharat AS.
PMID: 34453485
Chem Biol Drug Des. 2021 Aug 28; doi: 10.1111/cbdd.13945. Epub 2021 Aug 28.

Plant extracts and their bioactive compounds are considered as the promising options for green synthesis of nanoparticles instead expensive and hazardous materials. Here, Solanum xanthocarpum fruit was used for synthesis of silver nanoparticles (AgNP). The synthesized AgNPs were characterized...

Showing 25 to 36 of 157 entries