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Showing 25 to 36 of 1193 entries
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Toward a Molecular Lego Approach for the Diversity-Oriented Synthesis of Cyclodextrin Analogues Designed as Scaffolds for Multivalent Systems.

The Journal of organic chemistry

Lepage ML, Schneider JP, Bodlenner A, Compain P.
PMID: 26439895
J Org Chem. 2015 Nov 06;80(21):10719-33. doi: 10.1021/acs.joc.5b01938. Epub 2015 Oct 26.

A modular strategy has been developed to access a diversity of cyclic and acyclic oligosaccharide analogues designed as prefunctionalized scaffolds for the synthesis of multivalent ligands. This convergent approach is based on bifunctional sugar building blocks with two temporarily...

Conformational Change in the Mechanism of Inclusion of Ketoprofen in β-Cyclodextrin: NMR Spectroscopy, Ab Initio Calculations, Molecular Dynamics Simulations, and Photoreactivity.

The journal of physical chemistry. B

Guzzo T, Mandaliti W, Nepravishta R, Aramini A, Bodo E, Daidone I, Allegretti M, Topai A, Paci M.
PMID: 27689813
J Phys Chem B. 2016 Oct 20;120(41):10668-10678. doi: 10.1021/acs.jpcb.6b07913. Epub 2016 Oct 11.

Inclusion of drugs in cyclodextrins (CDs) is a recognized tool for modifying several properties such as solubility, stability, bioavailability, and so on. The photoreactive behavior of the β-CD/ketoprofen (KP) complex upon UV exposure showed a significant increase in photodecarboxylation,...

Supramolecular Recognition Induces Nonsynchronous Change of Dye Fluorescence Properties.

The Journal of organic chemistry

Pereira-Vilar A, Martin-Pastor M, Pessêgo M, García-Río L.
PMID: 27385129
J Org Chem. 2016 Aug 05;81(15):6587-95. doi: 10.1021/acs.joc.6b01230. Epub 2016 Jul 21.

Fluorescence behavior of 8-anilino-1-naphthalenesulfonate (ANS) reflects a blue-shift and fluorescence enhancement on decreasing solvent polarity, with both properties affected in a synchronous way in solvent mixtures where ANS senses a homogeneous solvation shell. ANS complexation by cyclodextrins or bovine...

Electroosmosis through α-Hemolysin That Depends on Alkali Cation Type.

The journal of physical chemistry letters

Piguet F, Discala F, Breton MF, Pelta J, Bacri L, Oukhaled A.
PMID: 26273988
J Phys Chem Lett. 2014 Dec 18;5(24):4362-7. doi: 10.1021/jz502360c. Epub 2014 Dec 08.

We demonstrate experimentally the existence of an electroosmotic flow (EOF) through the wild-type nanopore of α-hemolysin in a large range of applied voltages and salt concentrations for two different salts, LiCl and KCl. EOF controls the entry frequency and...

A Typical Metal-Ion-Responsive Color-Tunable Emitting Insulated π-Conjugated Polymer Film.

Angewandte Chemie (International ed. in English)

Hosomi T, Masai H, Fujihara T, Tsuji Y, Terao J.
PMID: 27383238
Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13427-13431. doi: 10.1002/anie.201603160. Epub 2016 Jul 07.

We report the synthesis of an insulated π-conjugated polymer containing 2,2'-bipyridine moieties as metal coordination sites. Metal coordination to the polymer enabled easy and reversible tuning of the luminescent color without changes to the main chain skeleton. The permethylated...

The Mechanism of Binding of Glucoamylase I from Aspergillus awamori var. kawachi to Cyclodextrins and Raw Starch.

Bioscience, biotechnology, and biochemistry

Goto M, Tanigawa K, Kanlayakrit W, Hayashida S.
PMID: 27315704
Biosci Biotechnol Biochem. 1994 Jan;58(1):49-54. doi: 10.1271/bbb.58.49.

Glucoamylase I (GAI) bound to β-cyclodextrin (β-CD) with the binding constants of Kd = 17.7 μm and n = 1.69. Binding resulted in formation of an inclusion complex, as indicated by the fact that organic guest compounds for β-CD...

Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin-steroid interaction.

Beilstein journal of organic chemistry

Caira MR, Bourne SA, Samsodien H, Smith VJ.
PMID: 26734107
Beilstein J Org Chem. 2015 Dec 16;11:2616-30. doi: 10.3762/bjoc.11.281. eCollection 2015.

The interaction between the potent anticancer agent 2-methoxyestradiol (2ME) and a series of cyclodextrins (CDs) was investigated in the solid state using thermal analysis and X-ray diffraction, while the possibility of enhancing its poor aqueous solubility with CDs was...

Co-solvation effect on the binding mode of the α-mangostin/β-cyclodextrin inclusion complex.

Beilstein journal of organic chemistry

Rungnim C, Phunpee S, Kunaseth M, Namuangruk S, Rungsardthong K, Rungrotmongkol T, Ruktanonchai U.
PMID: 26734079
Beilstein J Org Chem. 2015 Nov 25;11:2306-2317. doi: 10.3762/bjoc.11.251. eCollection 2015.

Cyclodextrins (CDs) have been extensively utilized as host molecules to enhance the solubility, stability and bioavailability of hydrophobic drug molecules through the formation of inclusion complexes. It was previously reported that the use of co-solvents in such studies may...

Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples.

Journal of analytical methods in chemistry

Shang Y, Luo J, Wang P, Zhao X, Ye C, Guo S.
PMID: 27437160
J Anal Methods Chem. 2016;2016:7862152. doi: 10.1155/2016/7862152. Epub 2016 Jun 29.

β-Cyclodextrins/acrylic acid modified magnetic gelatin was prepared and then employed as the magnetic solid-phase extraction (MSPE) sorbent for extraction of moxidectin in milk samples. Due to the rigidity of hydrophobic cavity of β-cyclodextrins and carboxyl groups of acrylic acid,...

Potential Use of Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for siRNA.

Pharmaceuticals (Basel, Switzerland)

Arima H, Motoyama K, Higashi T.
PMID: 24288043
Pharmaceuticals (Basel). 2011 Dec 30;5(1):61-78. doi: 10.3390/ph5010061.

Cyclodextrin (CyD)-based nanoparticles and polyamidoamine (PAMAM) starburst dendrimers (dendrimers) are used as novel carriers for DNA and RNA. Recently, small interfering RNA (siRNA) complex with β-CyD-containing polycations (CDP) having adamantine-PEG or adamantine-PEG-transferrin underwent a phase I study for treatment...

First Occurrence of Tetrazines in Aqueous Solution: Electrochemistry and Fluorescence.

Chemphyschem : a European journal of chemical physics and physical chemistry

Fritea L, Audebert P, Galmiche L, Gorgy K, Le Goff A, Villalonga R, Săndulescu R, Cosnier S.
PMID: 26534906
Chemphyschem. 2015 Dec 01;16(17):3695-9. doi: 10.1002/cphc.201500544. Epub 2015 Nov 04.

The photophysical and electrochemical properties of tetrazines substituted by linear 2,3-naphtalimide antennas and/or adamantane groups specifically dedicated to host-guest interactions with cyclodextrins are studied both in organic and aqueous media. In acetonitrile solvent, the reduction potential of tetrazine leading...

Separation of phthalates by cyclodextrin modified micellar electrokinetic chromatography: quantitation in perfumes.

Analytica chimica acta

Pérez-Fernández V, González MJ, García MÁ, Marina ML.
PMID: 23708286
Anal Chim Acta. 2013 Jun 11;782:67-74. doi: 10.1016/j.aca.2013.03.072. Epub 2013 Apr 22.

A new CE method has been developed for the simultaneous separation of a group of parent phthalates. Due to the neutral character of these compounds, the addition of several bile salts as surfactants (sodium cholate (SC), sodium deoxycholate (SDC),...

Showing 25 to 36 of 1193 entries