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Showing 61 to 69 of 69 entries
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The effects of cyclooxygenase inhibitors on the gastric emptying and small intestine transit in the male rats following traumatic brain injury.

Iranian journal of basic medical sciences

Keshavarzi Z, Khaksari M, Shahrokhi N.
PMID: 25140201
Iran J Basic Med Sci. 2014 Jun;17(6):406-10.

OBJECTIVES: This study was carried out to investigate the effects of COX-2 selective inhibitor (Celecoxib) or non-selective COX inhibitor (Ibuprofen) on gastrointestinal motility.MATERIALS AND METHODS: THE RATS WERE RANDOMLY DIVIDED INTO FIVE GROUPS INCLUDING: intact, sham, traumatic brain injury...

Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression.

Journal of gynecologic oncology

Lee JP, Hahn HS, Hwang SJ, Choi JY, Park JS, Lee IH, Kim TJ.
PMID: 23875078
J Gynecol Oncol. 2013 Jul;24(3):273-9. doi: 10.3802/jgo.2013.24.3.273. Epub 2013 Jul 04.

OBJECTIVE: The purpose of this study was to investigate whether selective cyclooxygenase (COX) inhibitors promote paclitaxel-induced apoptosis in taxane-resistant ovarian cancer cells by suppressing MDR1/P-glycoprotein (P-gp) expression.METHODS: Taxane-resistant ovarian cancer cells were cultured with paclitaxel alone or combined with...

In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines.

Journal of dentistry (Shiraz, Iran)

Hashemipour MA, Mehrabizadeh Honarmand H, Falsafi F, Tahmasebi Arashlo M, Rajabalian S, Gandjalikhan Nassab SA.
PMID: 27602398
J Dent (Shiraz). 2016 Sep;17(3):219-25.

STATEMENT OF THE PROBLEM: Use of cyclooxygenase inhibitors as chemotherapy agents has attracted the attention of a large number of investigators in recent years. Given the importance of cancer therapy, only a limited number of studies have been carried...

Cyclic Systems Distribution Along Similarity Measures: Insights for an Application to Activity Landscape Modeling.

Molecular informatics

Pérez-Villanueva J, Méndez-Lucio O, Soria-Arteche O, Izquierdo T, Concepción Lozada M, Gloria-Greimel WA, Medina-Franco JL.
PMID: 27481279
Mol Inform. 2013 Feb;32(2):179-90. doi: 10.1002/minf.201200127. Epub 2013 Feb 10.

The emerging concept of the activity landscape has been widely applied for structureactivity relationships (SAR) characterization. Since chemical space representation plays a crucial role in activity landscape modeling, an adequate selection of similarity measures is desirable. Herein a set...

Aspirin Responsive Thrombotic Complications in Thrombocythemia Vera. A Novel Platelet-Mediated Arterial Thrombophilia.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Michiels JJ.
PMID: 27264763
Turk J Haematol. 2002 Jun 05;19(2):225-33.

Erythromelalgia is the main, pathognomonic and presenting symptom in patients with Essential Thrombocythemia and thrombocythemia associated with Polycythemia Vera. Complete relief of erythromelalgic and acrocyanotic pain is obtained with the cyclooxygenase inhibitors aspirin and indomethacin, but not with sodiumsalicylate,...

Response to "No Obvious Extra Cardiovascular Risk Associated With Low-Dose NSAIDs," "Do NSAIDs Actually Protect Against Myocardial Infarction and Death?," and "Are Myocardial Infarctions and Death in Healthy Individuals Associated With the Use of Cyclooxygenase Inhibitors?".

Clinical pharmacology and therapeutics

Fosbøl EL, Gislason GH, Køber L, Torp-Pedersen C.
PMID: 28547832
Clin Pharmacol Ther. 2009 Dec;86(6):602-604. doi: 10.1038/clpt.2009.204.

No abstract available.

Assessment of Platelet Function in Traumatic Brain Injury-A Retrospective Observational Study in the Neuro-Critical Care Setting.

Frontiers in neurology

Lindblad C, Thelin EP, Nekludov M, Frostell A, Nelson DW, Svensson M, Bellander BM.
PMID: 29434566
Front Neurol. 2018 Jan 26;9:15. doi: 10.3389/fneur.2018.00015. eCollection 2018.

BACKGROUND: Despite seemingly functional coagulation, hemorrhagic lesion progression is a common and devastating condition following traumatic brain injury (TBI), stressing the need for new diagnostic techniques. Multiple electrode aggregometry (MEA) measures platelet function and could aid in coagulopathy assessment...

Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants.

Korean journal of pediatrics

Shin J, Lee EH, Lee JH, Choi BM, Hong YS.
PMID: 28690644
Korean J Pediatr. 2017 Jun;60(6):175-180. doi: 10.3345/kjp.2017.60.6.175. Epub 2017 Jun 22.

PURPOSE: Plasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal closure. We investigated the usefulness of serial BNP measurement...

Current Controversy on Platelets and Patent Ductus Arteriosus Closure in Preterm Infants.

Frontiers in pediatrics

Sallmon H, Timme N, Atasay B, Erdeve Ö, Hansmann G, Singh Y, Weber SC, Shelton EL.
PMID: 33718298
Front Pediatr. 2021 Feb 25;9:612242. doi: 10.3389/fped.2021.612242. eCollection 2021.

Platelets are critically involved in murine patent ductus arteriosus (PDA) closure. To date, the clinical significance of these findings in human preterm infants with PDA is still controversial. We discuss the available study data on the role of platelets...

Showing 61 to 69 of 69 entries