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Showing 25 to 36 of 93 entries
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A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal.

The primary care companion for CNS disorders

Bhatia MS, Kaur J, Gautam P.
PMID: 26644949
Prim Care Companion CNS Disord. 2015 May 21;17(3). doi: 10.4088/PCC.14l01762. eCollection 2015.

No abstract available.

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Bhatia MS, Kaur J, Gautam P. A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal. Prim Care Companion CNS Disord. 2015;17(3)doi: 10.4088/PCC.14l01762.
Bhatia, M. S., Kaur, J., & Gautam, P. (2015). A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal. The primary care companion for CNS disorders, 17(3), . https://doi.org/10.4088/PCC.14l01762
Bhatia, Manjeet S, et al. "A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal." The primary care companion for CNS disorders vol. 17,3 (2015). doi: https://doi.org/10.4088/PCC.14l01762
Bhatia MS, Kaur J, Gautam P. A Case of Serotonin Syndrome Following Cyproheptadine Withdrawal. Prim Care Companion CNS Disord. 2015 May 21;17(3). doi: 10.4088/PCC.14l01762. eCollection 2015. PMID: 26644949; PMCID: PMC4578901.
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Cyproheptadine in the treatment of reversible cerebral vasoconstriction syndrome.

Acta neurologica Belgica

Chima J, Mullaguri N, Fan T, George P, Newey CR.
PMID: 32895901
Acta Neurol Belg. 2021 Dec;121(6):1871-1874. doi: 10.1007/s13760-020-01487-z. Epub 2020 Sep 08.

No abstract available.

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Chima J, Mullaguri N, Fan T, et al. Cyproheptadine in the treatment of reversible cerebral vasoconstriction syndrome. Acta Neurol Belg. 2020;121(6):1871-1874doi: 10.1007/s13760-020-01487-z.
Chima, J., Mullaguri, N., Fan, T., George, P., & Newey, C. R. (2021). Cyproheptadine in the treatment of reversible cerebral vasoconstriction syndrome. Acta neurologica Belgica, 121(6), 1871-1874. https://doi.org/10.1007/s13760-020-01487-z
Chima, Jennifer, et al. "Cyproheptadine in the treatment of reversible cerebral vasoconstriction syndrome." Acta neurologica Belgica vol. 121,6 (2021): 1871-1874. doi: https://doi.org/10.1007/s13760-020-01487-z
Chima J, Mullaguri N, Fan T, George P, Newey CR. Cyproheptadine in the treatment of reversible cerebral vasoconstriction syndrome. Acta Neurol Belg. 2021 Dec;121(6):1871-1874. doi: 10.1007/s13760-020-01487-z. Epub 2020 Sep 08. PMID: 32895901.
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Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS).

Molecular pharmaceutics

Fuguet E, Subirats X, Ràfols C, Bosch E, Avdeef A.
PMID: 33983741
Mol Pharm. 2021 Jun 07;18(6):2311-2321. doi: 10.1021/acs.molpharmaceut.1c00131. Epub 2021 May 13.

It is widely accepted that solubility-pH profiles of ionizable compounds follow the Henderson-Hasselbalch equation. However, several studies point out that compounds often undergo additional processes in saturated solutions, such as sub-micellar oligomerization, micellar aggregation, or drug-buffer complexation among others,...

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Fuguet E, Subirats X, Ràfols C, et al. Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS). Mol Pharm. 2021;18(6):2311-2321doi: 10.1021/acs.molpharmaceut.1c00131.
Fuguet, E., Subirats, X., Ràfols, C., Bosch, E., & Avdeef, A. (2021). Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS). Molecular pharmaceutics, 18(6), 2311-2321. https://doi.org/10.1021/acs.molpharmaceut.1c00131
Fuguet, Elisabet, et al. "Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS)." Molecular pharmaceutics vol. 18,6 (2021): 2311-2321. doi: https://doi.org/10.1021/acs.molpharmaceut.1c00131
Fuguet E, Subirats X, Ràfols C, Bosch E, Avdeef A. Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions Using Mass Spectrometry (ESI-Q-TOF-MS/MS). Mol Pharm. 2021 Jun 07;18(6):2311-2321. doi: 10.1021/acs.molpharmaceut.1c00131. Epub 2021 May 13. PMID: 33983741.
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Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series.

SAGE open medical case reports

Keith P, Saint-Jour M, Pusey F, Hodges J, Jalali F, Scott LK.
PMID: 34290872
SAGE Open Med Case Rep. 2021 Jul 08;9:2050313X211032089. doi: 10.1177/2050313X211032089. eCollection 2021.

Clinicians and researchers have reported an array of neurological abnormalities in coronavirus disease 2019 (COVID-19), and while serotonin excess has been observed we are unaware of reports of central nervous system serotonin toxicity in COVID-19. We present two cases...

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Keith P, Saint-Jour M, Pusey F, et al. Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series. SAGE Open Med Case Rep. 2021;9:2050313X211032089doi: 10.1177/2050313X211032089.
Keith, P., Saint-Jour, M., Pusey, F., Hodges, J., Jalali, F., & Scott, L. K. (2021). Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series. SAGE open medical case reports, 92050313X211032089. https://doi.org/10.1177/2050313X211032089
Keith, Philip, et al. "Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series." SAGE open medical case reports vol. 9 (2021): 2050313X211032089. doi: https://doi.org/10.1177/2050313X211032089
Keith P, Saint-Jour M, Pusey F, Hodges J, Jalali F, Scott LK. Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series. SAGE Open Med Case Rep. 2021 Jul 08;9:2050313X211032089. doi: 10.1177/2050313X211032089. eCollection 2021. PMID: 34290872; PMCID: PMC8274092.
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Blockade of 5-HT.

Journal of neurophysiology

Goodlich BI, Horan SA, Kavanagh JJ.
PMID: 34936830
J Neurophysiol. 2022 Jan 01;127(1):150-160. doi: 10.1152/jn.00470.2021. Epub 2021 Dec 22.

Serotonin (5-HT) is a neuromodulator that is critical for regulating the excitability of spinal motoneurons and the generation of muscle torque. However, the role of 5-HT in modulating human motor unit activity during rapid contractions has yet to be...

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Goodlich BI, Horan SA, Kavanagh JJ. Blockade of 5-HT. J Neurophysiol. 2021;127(1):150-160doi: 10.1152/jn.00470.2021.
Goodlich, B. I., Horan, S. A., & Kavanagh, J. J. (2022). Blockade of 5-HT. Journal of neurophysiology, 127(1), 150-160. https://doi.org/10.1152/jn.00470.2021
Goodlich, Benjamin I, et al. "Blockade of 5-HT." Journal of neurophysiology vol. 127,1 (2022): 150-160. doi: https://doi.org/10.1152/jn.00470.2021
Goodlich BI, Horan SA, Kavanagh JJ. Blockade of 5-HT. J Neurophysiol. 2022 Jan 01;127(1):150-160. doi: 10.1152/jn.00470.2021. Epub 2021 Dec 22. PMID: 34936830.
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Review of the pharmacotherapy of irritability of autism.

Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent

Elbe D, Lalani Z.
PMID: 22548111
J Can Acad Child Adolesc Psychiatry. 2012 May;21(2):130-46.

OBJECTIVE: To review the randomized controlled trial data regarding pharmacotherapy of irritability of autism.METHOD: A LITERATURE REVIEW WAS CONDUCTED USING THE MEDLINE SEARCH TERMS: 'autism' OR 'autism spectrum disorder' with the following limits: Randomized Controlled Trials (RCTs), human trials,...

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Elbe D, Lalani Z. Review of the pharmacotherapy of irritability of autism. J Can Acad Child Adolesc Psychiatry. 2012;21(2):130-46
Elbe, D., & Lalani, Z. (2012). Review of the pharmacotherapy of irritability of autism. Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent, 21(2), 130-46.
Elbe, Dean, and Lalani, Zaahira. "Review of the pharmacotherapy of irritability of autism." Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent vol. 21,2 (2012): 130-46.
Elbe D, Lalani Z. Review of the pharmacotherapy of irritability of autism. J Can Acad Child Adolesc Psychiatry. 2012 May;21(2):130-46. PMID: 22548111; PMCID: PMC3338180.
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Blockade of 5-HT.

Journal of neurophysiology

Goodlich BI, Horan SA, Kavanagh JJ.
PMID: 34936830
J Neurophysiol. 2021 Dec 22; doi: 10.1152/jn.00470.2021. Epub 2021 Dec 22.

Serotonin (5-HT) is a neuromodulator that is critical for regulating the excitability of spinal motoneurons and the generation of muscle torque. However, the role of 5-HT in modulating human motor unit activity during rapid contractions has yet to be...

Cite
Goodlich BI, Horan SA, Kavanagh JJ. Blockade of 5-HT. J Neurophysiol. 2021;doi: 10.1152/jn.00470.2021.
Goodlich, B. I., Horan, S. A., & Kavanagh, J. J. (2021). Blockade of 5-HT. Journal of neurophysiology, . https://doi.org/10.1152/jn.00470.2021
Goodlich, Benjamin Ian, et al. "Blockade of 5-HT." Journal of neurophysiology vol. (2021). doi: https://doi.org/10.1152/jn.00470.2021
Goodlich BI, Horan SA, Kavanagh JJ. Blockade of 5-HT. J Neurophysiol. 2021 Dec 22; doi: 10.1152/jn.00470.2021. Epub 2021 Dec 22. PMID: 34936830.
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Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report.

Toxicology reports

Thumtecho S, Wainipitapong S, Suteparuk S.
PMID: 34815949
Toxicol Rep. 2021 Nov 06;8:1846-1848. doi: 10.1016/j.toxrep.2021.11.003. eCollection 2021.

BACKGROUND: Psychotropic drugs can cause neurological effects when overdosed. This study reports a case of psychotropic drugs overdose presenting with serotonin toxicity and encephalopathy.CASE PRESENTATION: A 20-year-old female with major depression presented with agitation 3 h after an overdose...

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Thumtecho S, Wainipitapong S, Suteparuk S. Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report. Toxicol Rep. 2021;8:1846-1848doi: 10.1016/j.toxrep.2021.11.003.
Thumtecho, S., Wainipitapong, S., & Suteparuk, S. (2021). Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report. Toxicology reports, 81846-1848. https://doi.org/10.1016/j.toxrep.2021.11.003
Thumtecho, Suthimon, et al. "Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report." Toxicology reports vol. 8 (2021): 1846-1848. doi: https://doi.org/10.1016/j.toxrep.2021.11.003
Thumtecho S, Wainipitapong S, Suteparuk S. Escitalopram, bupropion, lurasidone, lamotrigine and possible vortioxetine overdose presented with serotonin syndrome and diffuse encephalopathy: A case report. Toxicol Rep. 2021 Nov 06;8:1846-1848. doi: 10.1016/j.toxrep.2021.11.003. eCollection 2021. PMID: 34815949; PMCID: PMC8591335.
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Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract.

European journal of pharmacology

de Oliveira DMN, Oliveira-Silva CA, Pinheiro CG, de Carvalho EF, Gadelha KKL, Lima-Silva K, Cavalcante AKM, Belém MO, Paula SM, Dos Santos AA, Magalhães PJC.
PMID: 34265293
Eur J Pharmacol. 2021 Oct 05;908:174339. doi: 10.1016/j.ejphar.2021.174339. Epub 2021 Jul 12.

This study tested the effects of β-methylphenylethylamine (β-MPEA) and octopamine on contractile parameters of the gastrointestinal tract in rats. We hypothesized that some of their effects result from interactions with trace amine (TA)-associated receptors or serotoninergic 5-hydroxytryptamine (5-HT) receptors....

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de Oliveira DMN, Oliveira-Silva CA, Pinheiro CG, et al. Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract. Eur J Pharmacol. 2021;908:174339doi: 10.1016/j.ejphar.2021.174339.
de Oliveira, D. M. N., Oliveira-Silva, C. A., Pinheiro, C. G., de Carvalho, E. F., Gadelha, K. K. L., Lima-Silva, K., Cavalcante, A. K. M., Belém, M. O., Paula, S. M., Dos Santos, A. A., & Magalhães, P. J. C. (2021). Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract. European journal of pharmacology, 908174339. https://doi.org/10.1016/j.ejphar.2021.174339
de Oliveira, Daniel Maia Nogueira, et al. "Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract." European journal of pharmacology vol. 908 (2021): 174339. doi: https://doi.org/10.1016/j.ejphar.2021.174339
de Oliveira DMN, Oliveira-Silva CA, Pinheiro CG, de Carvalho EF, Gadelha KKL, Lima-Silva K, Cavalcante AKM, Belém MO, Paula SM, Dos Santos AA, Magalhães PJC. Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract. Eur J Pharmacol. 2021 Oct 05;908:174339. doi: 10.1016/j.ejphar.2021.174339. Epub 2021 Jul 12. PMID: 34265293.
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Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review.

Frontiers in pediatrics

Bertrand V, Massy N, Vegas N, Gras V, Chalouhi C, Tavolacci MP, Abadie V.
PMID: 34676184
Front Pediatr. 2021 Sep 29;9:712413. doi: 10.3389/fped.2021.712413. eCollection 2021.

No abstract available.

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Bertrand V, Massy N, Vegas N, et al. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. Front Pediatr. 2021;9:712413doi: 10.3389/fped.2021.712413.
Bertrand, V., Massy, N., Vegas, N., Gras, V., Chalouhi, C., Tavolacci, M. P., & Abadie, V. (2021). Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. Frontiers in pediatrics, 9712413. https://doi.org/10.3389/fped.2021.712413
Bertrand, Valérie, et al. "Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review." Frontiers in pediatrics vol. 9 (2021): 712413. doi: https://doi.org/10.3389/fped.2021.712413
Bertrand V, Massy N, Vegas N, Gras V, Chalouhi C, Tavolacci MP, Abadie V. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. Front Pediatr. 2021 Sep 29;9:712413. doi: 10.3389/fped.2021.712413. eCollection 2021. PMID: 34676184; PMCID: PMC8525494.
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Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis.

European journal of pain (London, England)

Pinardi G, Pelissier T, Miranda HF.
PMID: 10700329
Eur J Pain. 1998;2(4):343-350. doi: 10.1016/s1090-3801(98)90032-5.

Tramadol is a widely-used analgesic for pre- and post-operative pain which has a different pharmacological profile to that of classical opioids, since it does not induce respiratory depression, constipation, sedation, tolerance or dependence. However, tramadol frequently produces nausea and...

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Pinardi G, Pelissier T, Miranda HF. Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis. Eur J Pain. 1998;2(4):343-350doi: 10.1016/s1090-3801(98)90032-5.
Pinardi, G., Pelissier, T., & Miranda, H. F. (1998). Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis. European journal of pain (London, England), 2(4), 343-350. https://doi.org/10.1016/s1090-3801(98)90032-5
Pinardi, et al. "Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis." European journal of pain (London, England) vol. 2,4 (1998): 343-350. doi: https://doi.org/10.1016/s1090-3801(98)90032-5
Pinardi G, Pelissier T, Miranda HF. Interactions in the antinociceptive effect of tramadol in mice: an isobolographic analysis. Eur J Pain. 1998;2(4):343-350. doi: 10.1016/s1090-3801(98)90032-5. PMID: 10700329.
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Pharmacological characterisation of 5-hydroxytryptamine-induced contractile effects in the isolated gut of the lepidopteran caterpillar Spodoptera frugiperda.

Journal of insect physiology

Howarth CJ, Prince RI, Dyker H, Lösel PM, Seinsche A, Osborne RH.
PMID: 12770131
J Insect Physiol. 2002 Jan;48(1):43-52. doi: 10.1016/s0022-1910(01)00142-1.

The indolealkylamine 5-hydroxytryptamine (5-HT, 0.1nM-1&mgr;M) caused dose-dependent increases in the number of contractions observed in guts isolated from the caterpillar Spodoptera frugiperda. Of the 5-HT analogues tested for agonist action, 2-methyl-5-HT (0.1-10&mgr;M) was a full agonist with reduced potency...

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Howarth CJ, Prince RI, Dyker H, et al. Pharmacological characterisation of 5-hydroxytryptamine-induced contractile effects in the isolated gut of the lepidopteran caterpillar Spodoptera frugiperda. J Insect Physiol. 2002;48(1):43-52doi: 10.1016/s0022-1910(01)00142-1.
Howarth, C. J., Prince, R. I., Dyker, H., Lösel, P. M., Seinsche, A., & Osborne, R. H. (2002). Pharmacological characterisation of 5-hydroxytryptamine-induced contractile effects in the isolated gut of the lepidopteran caterpillar Spodoptera frugiperda. Journal of insect physiology, 48(1), 43-52. https://doi.org/10.1016/s0022-1910(01)00142-1
Howarth, C J., et al. "Pharmacological characterisation of 5-hydroxytryptamine-induced contractile effects in the isolated gut of the lepidopteran caterpillar Spodoptera frugiperda." Journal of insect physiology vol. 48,1 (2002): 43-52. doi: https://doi.org/10.1016/s0022-1910(01)00142-1
Howarth CJ, Prince RI, Dyker H, Lösel PM, Seinsche A, Osborne RH. Pharmacological characterisation of 5-hydroxytryptamine-induced contractile effects in the isolated gut of the lepidopteran caterpillar Spodoptera frugiperda. J Insect Physiol. 2002 Jan;48(1):43-52. doi: 10.1016/s0022-1910(01)00142-1. PMID: 12770131.
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Showing 25 to 36 of 93 entries