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Showing 13 to 24 of 309 entries
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Meningiomas.

Current treatment options in neurology

Chamberlain MC.
PMID: 11123860
Curr Treat Options Neurol. 2001 Jan;3(1):67-76. doi: 10.1007/s11940-001-0025-6.

Meningiomas are extra-axial brain tumors of middle-to-late adult life and show a predominance in women. Overall, 90% of meningiomas are benign, 6% atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have it removed surgically,...

Intracerebral Meningiomas.

Current treatment options in neurology

Chamberlain MC.
PMID: 15157407
Curr Treat Options Neurol. 2004 Jul;6(4):297-305. doi: 10.1007/s11940-004-0029-0.

Meningiomas are extra-axial brain tumors of middle to late adult life, and they have a female predominance. Overall, 90% of meningiomas are benign, 6% are atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have...

Neutropenia and Neutropenic Complications in ABVD Chemotherapy for Hodgkin Lymphoma.

Advances in hematology

Vakkalanka B, Link BK.
PMID: 21687649
Adv Hematol. 2011;2011:656013. doi: 10.1155/2011/656013. Epub 2011 May 02.

A combination of Adriamycin (a.k.a. Doxorubicin), Bleomycin, Vinblastine, and Dacarbazine (ABVD) is the most commonly used chemotherapy regime for Hodgkin lymphoma. This highly effective treatment is associated with a significant risk of neutropenia. Various strategies are adopted to counter...

Physical and chemical stability of palonosetron hydrochloride with dacarbazine and with methylprednisolone sodium succinate during simulated y-site administration.

International journal of pharmaceutical compounding

Trissel LA, Zhang Y, Xu QA.
PMID: 23974237
Int J Pharm Compd. 2006 May-Jun;10(3):234-6.

The objective of this study was to evaluate the physical and chemical stability of mixtures of undiluted palonosetron hydrochloride 50 micrograms/mL with dacarbazine 4 mg/mL and with methylprednisolone sodium succinate 5 mg/mL in 5% dextrose injection during simulated Y-site...

Dacarbazine mediate antimelanoma effects via NK cells.

Oncoimmunology

Hervieu A, Mignot G, Ghiringhelli F.
PMID: 23734324
Oncoimmunology. 2013 Apr 01;2(4):e23714. doi: 10.4161/onci.23714.

Melanoma is a highly chemoresistant and metastatic tumor that, in the absence of

The evolution in melanoma treatment as a reflection of precision-oriented medicine.

Oncology letters

Kushnir I, Merimsky O.
PMID: 23420786
Oncol Lett. 2013 Feb;5(2):424-426. doi: 10.3892/ol.2012.1065. Epub 2012 Dec 05.

Until recently, metastatic melanoma was a disease with limited treatment options and a poor prognosis. Dacarbazine was accepted as the standard treatment for melanoma in the 1970s, and despite inducing an overall survival of approximately 7.4 months, it remained...

Rapid desensitization for brentuximab vedotin (Adceteris.

Clinical and molecular allergy : CMA

Di Girolamo A, Albanesi M, Sinisi A, Nettis E, Di Bona D, Caiaffa MF, Macchia L.
PMID: 30386181
Clin Mol Allergy. 2018 Oct 29;16:22. doi: 10.1186/s12948-018-0100-0. eCollection 2018.

BACKGROUND: Brentuximab vedotin (BV) is an antibody-drug conjugate formed by an anti-CD30 chimeric IgGCASE PRESENTATION: A 20-year old male patient was diagnosed with Hodgkin lymphoma in July 2014. The first line treatment with adriblastine, bleomicine, vinblastine and dacarbazine lead...

Near Complete Response in a Patient with Classical Hodgkin Lymphoma Treated with Brentuximab Vedotin Concurrent with Radiation Therapy.

Case reports in oncology

Montana W, Buck DA, Smith T.
PMID: 29158727
Case Rep Oncol. 2017 Sep 06;10(3):795-801. doi: 10.1159/000479224. eCollection 2017.

Brentuximab vedotin, an antibody drug conjugate that delivers monomethyl auristatin E into CD-30 expressing cells is FDA approved for the treatment of patients with Hodgkin lymphoma after the failure of autologous stem cell transplantation or at least 2 prior...

Modeling the economic outcomes of immuno-oncology drugs: alternative model frameworks to capture clinical outcomes.

ClinicoEconomics and outcomes research : CEOR

Gibson EJ, Begum N, Koblbauer I, Dranitsaris G, Liew D, McEwan P, Tahami Monfared AA, Yuan Y, Juarez-Garcia A, Tyas D, Lees M.
PMID: 29563820
Clinicoecon Outcomes Res. 2018 Mar 08;10:139-154. doi: 10.2147/CEOR.S144208. eCollection 2018.

BACKGROUND: Economic models in oncology are commonly based on the three-state partitioned survival model (PSM) distinguishing between progression-free and progressive states. However, the heterogeneity of responses observed in immuno-oncology (I-O) suggests that new approaches may be appropriate to reflect...

Time trends of consumption and costs of drugs in a cancer referral centre.

International journal of oncology

Marfella A, Perrone F, Creazzola S, Salzano M, Monfardini S.
PMID: 21533426
Int J Oncol. 1997 Mar;10(3):641-4. doi: 10.3892/ijo.10.3.641.

This study is a descriptive analysis of the consumption and the costs of antineoplastic chemotherapeutic agents and of the major groups of drugs used for supportive therapy during the 1990-1995 period, at the National Cancer Institute of Naples, Italy....

Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance.

Cancer & metabolism

Malvi P, Chaube B, Singh SV, Mohammad N, Pandey V, Vijayakumar MV, Radhakrishnan RM, Vanuopadath M, Nair SS, Nair BG, Bhat MK.
PMID: 27980732
Cancer Metab. 2016 Dec 07;4:21. doi: 10.1186/s40170-016-0162-8. eCollection 2016.

BACKGROUND: Obesity-related cellular, metabolic, and molecular alterations have been shown to increase cancer risk and tumor progression and are associated with poorer therapeutic outcome in cancer patients. However, the impact of obesity and weight-control interventions on the therapeutic response...

Metastatic Malignant Paraganglioma: A Case Report and Review of Literature.

World journal of oncology

Prades CA, Atassi B, Nazeer H.
PMID: 29147442
World J Oncol. 2017 Jun;8(3):92-95. doi: 10.14740/wjon1033w. Epub 2017 Jun 09.

Metastasis is a rare presentation of non-secretory paraganglioma. Consequently, there is no standard of care for the treatment of metastatic malignant paraganglioma. The most widely used chemotherapy regimen for non-resectable cases includes cyclophosphamide, vincristine, and dacarbazine (CVD). CVD has...

Showing 13 to 24 of 309 entries