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Showing 13 to 24 of 48 entries
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Molecular modelling studies unveil potential binding sites on human serum albumin for selected experimental and .

Saudi journal of biological sciences

Gurung AB, Ali MA, Lee J, Farah MA, Al-Anazi KM, Sami H.
PMID: 34548836
Saudi J Biol Sci. 2022 Jan;29(1):53-64. doi: 10.1016/j.sjbs.2021.09.042. Epub 2021 Sep 17.

Human serum albumin (HSA) is the most prevalent protein in the blood plasma which binds an array of exogenous compounds. Drug binding to HSA is an important consideration when developing new therapeutic molecules, and it also aids in understanding...

Molecular modelling studies unveil potential binding sites on human serum albumin for selected experimental and .

Saudi journal of biological sciences

Gurung AB, Ali MA, Lee J, Farah MA, Al-Anazi KM, Sami H.
PMID: 34548836
Saudi J Biol Sci. 2022 Jan;29(1):53-64. doi: 10.1016/j.sjbs.2021.09.042. Epub 2021 Sep 17.

Human serum albumin (HSA) is the most prevalent protein in the blood plasma which binds an array of exogenous compounds. Drug binding to HSA is an important consideration when developing new therapeutic molecules, and it also aids in understanding...

Sodium Valproate Versus Dopamine Antagonists for Acute Migraine in the Emergency Department: A Systematic Review.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Viau JA, Patel D, Cheng W, Cortel-LeBlanc M, Nath A, Perry JJ.
PMID: 34382533
Can J Neurol Sci. 2021 Aug 12;1-8. doi: 10.1017/cjn.2021.195. Epub 2021 Aug 12.

BACKGROUND: Migraine is a common primary headache disorder diagnosed in the emergency department (ED). This systematic review sought to compare the efficacy of sodium valproate (SV) to dopamine antagonists (DA) in relieving pain due to acute migraine.METHODS: Two research...

Treatment of raised intracranial pressure following traumatic brain injury.

Critical reviews in neurosurgery : CR

Beaumont A, Marmarou A.
PMID: 10436209
Crit Rev Neurosurg. 1999 Jul 28;9(4):207-216. doi: 10.1007/s003290050135.

Appropriate treatment of raised intracranial pressure (ICP) after traumatic brain injury (TBI) remains a controversial topic in neurotraumatology. Several techniques are employed clinically, which include vasopressors, osmotically active substances, hyperventilation, and decompressive surgery. This article reviews six recent papers...

Treatment of acute migraine in the pediatric population.

Current treatment options in neurology

O'Brien HL, Kabbouche MA, Hershey AD.
PMID: 20842580
Curr Treat Options Neurol. 2010 May;12(3):178-85. doi: 10.1007/s11940-010-0069-6.

OPINION STATEMENT: The recognition of the diagnosis of migraine in the pediatric population is increasing. Early and aggressive treatment of migraine in children and adolescents with the use of over-the-counter medications has proven effective. In addition, the off-label use...

Relationships among ergot alkaloids, cytochrome P450 activity, and beef steer growth.

Frontiers in chemistry

Rosenkrans CF, Ezell NS.
PMID: 25815288
Front Chem. 2015 Mar 11;3:16. doi: 10.3389/fchem.2015.00016. eCollection 2015.

Determining a grazing animal's susceptibility to ergot alkaloids has been a research topic for decades. Our objective was to determine if the Promega™ P450-Glo assay could be used to indirectly detect ergot alkaloids or their metabolites in urine of...

Dihydroergotamine and triptan use to treat migraine during pregnancy and the risk of adverse pregnancy outcomes.

Scientific reports

Bérard A, Strom S, Zhao JP, Kori S, Albrecht D.
PMID: 34588467
Sci Rep. 2021 Sep 29;11(1):19302. doi: 10.1038/s41598-021-97092-y.

Migraine is prevalent during pregnancy. Antimigraine medications such as dihydroergotamine (DHE) and triptans have been associated with adverse pregnancy outcomes in individual studies but lack of consensus remains. We compared the risk of prematurity, low birth weight (LBW), major...

Saudi journal of biological sciences

Gurung AB, Ali MA, Lee J, Abul Farah M, Al-Anazi KM.
PMID: 32837219
Saudi J Biol Sci. 2020 Oct;27(10):2674-2682. doi: 10.1016/j.sjbs.2020.06.005. Epub 2020 Jun 10.

Coronaviruses with the largest viral genomes are positive-sense RNA viruses associated with a history of global epidemics such as the severe respiratory syndrome (SARS), the Middle East respiratory syndrome (MERS) and recently the coronavirus disease 2019 (COVID-19). There has...

Standardized Headache Therapy in the Pediatric Emergency Department Using Improvement Methodology.

Pediatric quality & safety

Vukovic AA, Hariharan S, Caruso MC, Zellner SM, Kabbouche M, Porter SC, Murtagh-Kurowski E.
PMID: 34345756
Pediatr Qual Saf. 2021 Jul 28;6(4):e443. doi: 10.1097/pq9.0000000000000443. eCollection 2021.

INTRODUCTION: Primary headache is a common cause of pediatric emergency department (PED) visits. Without published guidelines to direct treatment options, various strategies lacking evidence are often employed. This study aims to standardize primary headache treatment in the PED by...

Dihydroergotamine infusion for pediatric refractory headache: A retrospective chart review.

Headache

Srouji R, Schenkel SR, Forbes P, Cahill JE.
PMID: 34105158
Headache. 2021 May;61(5):777-789. doi: 10.1111/head.14117.

BACKGROUND: Headaches are a common symptom in children. Children with refractory headaches may be admitted for inpatient treatment with intravenous dihydroergotamine mesylate (DHE). However, very few studies have characterized these patients and their treatment outcomes using validated, self-reported, pain...

Molecular modelling studies unveil potential binding sites on human serum albumin for selected experimental and .

Saudi journal of biological sciences

Bahadur Gurung A, Ajmal Ali M, Lee J, Abul Farah M, Mashay Al-Anazi K, Sami H.
PMID: 34548836
Saudi J Biol Sci. 2021 Sep 17; doi: 10.1016/j.sjbs.2021.09.042. Epub 2021 Sep 17.

Human serum albumin (HSA) is the most prevalent protein in the blood plasma which binds an array of exogenous compounds. Drug binding to HSA is an important consideration when developing new therapeutic molecules, and it also aids in understanding...

Second-line interventions for migraine in the emergency department: A narrative review.

Headache

Kazi F, Manyapu M, Fakherddine M, Mekuria K, Friedman BW.
PMID: 34806767
Headache. 2021 Nov 22; doi: 10.1111/head.14239. Epub 2021 Nov 22.

OBJECTIVE: Millions of patients present to US emergency departments (ED) annually for the treatment of migraine. First-line treatments, including metoclopramide, prochlorperazine, and sumatriptan, fail to provide sufficient relief in up to one-third of treated patients. In this narrative review,...

Showing 13 to 24 of 48 entries