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Showing 37 to 48 of 48 entries
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Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type-B receptor 2.

FEBS open bio

Suzuki K, Aimi T, Ishihara T, Mizushima T.
PMID: 27419051
FEBS Open Bio. 2016 Apr 01;6(5):461-8. doi: 10.1002/2211-5463.12056. eCollection 2016 May.

Ephrin type-B receptor 2 (EphB2) is a member of the receptor tyrosine kinase family and plays an important role in learning and memory functions. In patients with Alzheimer's disease (AD) and in mouse models of AD, a reduction in...

Treatment of headache in the elderly.

Current treatment options in neurology

Hershey LA, Bednarczyk EM.
PMID: 23054583
Curr Treat Options Neurol. 2013 Feb;15(1):56-62. doi: 10.1007/s11940-012-0205-6.

OPINION STATEMENT: Most primary headaches in the elderly are similar to those in younger patients (tension, migraine, and cluster), but there are some differences, such as late-life migraine accompaniments and hypnic headaches. Although migraine in younger persons usually presents...

Second-line interventions for migraine in the emergency department: A narrative review.

Headache

Kazi F, Manyapu M, Fakherddine M, Mekuria K, Friedman BW.
PMID: 34806767
Headache. 2021 Nov;61(10):1467-1474. doi: 10.1111/head.14239. Epub 2021 Nov 22.

OBJECTIVE: Millions of patients present to US emergency departments (ED) annually for the treatment of migraine. First-line treatments, including metoclopramide, prochlorperazine, and sumatriptan, fail to provide sufficient relief in up to one-third of treated patients. In this narrative review,...

Short Term Oral Methylergonovine Maleate Prophylaxis for Status Migrainosus. Case Series and Review of Literature.

Frontiers in neurology

Haque N, Tariq N.
PMID: 30967829
Front Neurol. 2019 Mar 20;10:201. doi: 10.3389/fneur.2019.00201. eCollection 2019.

No abstract available.

DHE-Induced Peripheral Arterial Vasospasm in Primary Raynaud Phenomenon: Case Report.

The Neurohospitalist

Khalife J, Lauritsen CG, Liang J, Shah SO.
PMID: 30915191
Neurohospitalist. 2019 Apr;9(2):113-115. doi: 10.1177/1941874418797764. Epub 2018 Sep 11.

Dihydroergotamine (DHE) is primarily a serotonin 5HT1B and 5HT1D receptor agonist used for acute migraine treatment. It is associated with acute vasoconstriction mediated through the 5HT1B receptor and is contraindicated in patients with history of cardiac disease and peripheral...

Acute coronary syndrome and transient global amnesia with sumatriptan.

The American journal of emergency medicine

Lee E, Ghafoor N, Jefri M, Black AD, Calello DP, Santos CD.
PMID: 34625330
Am J Emerg Med. 2021 Sep 11; doi: 10.1016/j.ajem.2021.09.019. Epub 2021 Sep 11.

Triptans are potent serotoninergic vasoconstrictors. They are generally avoided in elderly patients age greater than 65 or in patients with a history of CAD. Although there are reported cases of Acute Coronary Syndrome (ACS) or Transient Global Amnesia (TGA)...

Everything old is new again.

Headache

Freitag FG.
PMID: 34350590
Headache. 2021 Sep;61(8):1286. doi: 10.1111/head.14181. Epub 2021 Aug 05.

No abstract available.

The optimal management of headaches in children and adolescents.

Therapeutic advances in neurological disorders

Kacperski J, Kabbouche MA, O'Brien HL, Weberding JL.
PMID: 26788131
Ther Adv Neurol Disord. 2016 Jan;9(1):53-68. doi: 10.1177/1756285615616586.

The recognition of the diagnosis of migraine in children is increasing. Early and aggressive treatment of migraine in this population with the use of over-the-counter medications has proven effective. The off-label use of many migraine-specific medications is often accepted...

Causes and mechanisms of primary headaches: toward a bio-behavioral model.

Italian journal of neurological sciences

Buzzi MG, Pellegrino MG, Bellantonio P.
PMID: 27315254
Ital J Neurol Sci. 1995 Dec;16(9):15-9. doi: 10.1007/BF02333240.

Pathophysiological mechanisms of primary headache remain obscure, despite of numerous hypotheses that have been postulated for either migraine and cluster headache. Human experimental models are not available, however, observation of clinical features of migraine or cluster headache attacks support...

Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-UV.

International journal of analytical chemistry

Jebali S, Belgacem C, Louhaichi MR, Bahri S, Latrous El Atarche L.
PMID: 31511775
Int J Anal Chem. 2019 Aug 15;2019:9685750. doi: 10.1155/2019/9685750. eCollection 2019.

A sensitive, precise, accurate, and specific isocratic reversed-phase high-performance liquid chromatographic (RP-HPLC) method for the simultaneous separation and determination of zolmitriptan, naratriptan, dihydroergotamine, ketotifen, and pizotifen in pharmaceutical formulations has been developed and validated. An experimental design was applied...

Development and Evaluation of an Integrated Outpatient Infusion Care Model for the Treatment of Pediatric Headache.

Pediatric neurology

Shapiro HFJ, Sant J, Minster A, Antonelli RC.
PMID: 34959159
Pediatr Neurol. 2021 Dec 02;127:41-47. doi: 10.1016/j.pediatrneurol.2021.11.012. Epub 2021 Dec 02.

BACKGROUND: Care for pediatric patients with headache often occurs in high-cost settings such as emergency departments (EDs) and inpatient settings. Outpatient infusion centers have the potential to reduce care costs for pediatric headache management.METHODS: In this quality improvement study,...

Elective Hospitalizations for Intractable Headache: Outcomes and Response Predictors.

Neurology. Clinical practice

Kiarashi J, Jion Y, Giglio B, Pavlovic J, Armand CE, Grosberg BM, Lipton RB, Vollbracht S, Robbins MS.
PMID: 34484886
Neurol Clin Pract. 2021 Jun;11(3):188-193. doi: 10.1212/CPJ.0000000000000965.

OBJECTIVE: To review our inpatient experience treating a variety of headache disorders with heterogeneous therapies and to determine outcomes and predictors of response.METHODS: We conducted an institutional review board-approved retrospective chart review of elective inpatient headache admissions from the...

Showing 37 to 48 of 48 entries