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Showing 25 to 36 of 576 entries
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Evidence that Neural Aromatization of Androgen Regulates the Expression of Sexual Behaviour in Female Musk Shrews.

Journal of neuroendocrinology

Rissman EF.
PMID: 19215490
J Neuroendocrinol. 1991 Aug 01;3(4):441-8. doi: 10.1111/j.1365-2826.1991.tb00301.x.

Abstract The experiments reported on here were conducted to test the hypothesis that sexual behaviour in the female musk shrew (Suncus murinus) is regulated by the neural aromatization of testosterone to oestradiol. In the first experiment ovariectomized animals received...

Androgen regulation of androgen receptor messenger ribonucleic Acid differs in rat prostate and selected brain areas.

Molecular and cellular neurosciences

Abdelgadir SE, Connolly PB, Resko JA.
PMID: 19912960
Mol Cell Neurosci. 1993 Dec;4(6):532-7. doi: 10.1006/mcne.1993.1065.

Androgens bind to specific high-affinity receptors (AR), thereby initiating gene transcription. We investigated the effects of testosterone (T), dihydrotestosterone (DHT), and 17beta-estradiol (E(2)) on AR transcription and binding in prostate, medial basal hypothalamus (MBH), preoptic area (POA), amygdala, hippocampus,...

A Telfairia Occidentalis Seed-incorporated Diet May Be Useful in Inhibiting the Induction of Experimental Andropause.

Annals of medical and health sciences research

Ejike C, Ezeanyika L.
PMID: 23209990
Ann Med Health Sci Res. 2012 Jan;2(1):41-5. doi: 10.4103/2141-9248.96936.

BACKGROUND: Andropause, a prevalent pathology of men, results from an imbalance in steroid hormone concentrations that often is associated with aging, and reduces the quality of life of the sufferer. This study investigates the usefulness of a diet containing...

Androgen-dependent and -independent aromatase activity coexists with androgen receptors in male Guinea-pig brain.

Journal of neuroendocrinology

Connolly PB, Roselli CE, Resko JA.
PMID: 19215538
J Neuroendocrinol. 1991 Dec 01;3(6):679-84. doi: 10.1111/j.1365-2826.1991.tb00333.x.

Abstract Using a microdissection technique we localized androgen receptors and aromatase activity (AA) in the brain of male guinea-pigs. In addition, we evaluated the effects of castration and androgen replacement on androgen receptor dynamics and induction of AA. In...

Clinical appraisal of abiraterone in the treatment of metastatic prostatic cancer: patient considerations, novel opportunities, and future directions.

OncoTargets and therapy

Bedoya DJ, Mitsiades N.
PMID: 23319868
Onco Targets Ther. 2013;6:9-18. doi: 10.2147/OTT.S24941. Epub 2013 Jan 03.

While androgen-deprivation therapy can induce dramatic clinical responses in advanced and metastatic prostate cancer, refractory disease (castration-resistant prostate cancer [CRPC]) eventually emerges. In recent years, several studies have demonstrated the importance of residual intratumoral androgens in maintaining androgen receptor...

Influence of sampling on steroid hormone patterns of beef from bulls and steers.

Meat science

Fritsche S, Schwarz FJ, Kirchgeßner M, Augustini C, Steinhart H.
PMID: 22060959
Meat Sci. 1998 Oct;50(2):257-64. doi: 10.1016/s0309-1740(98)00046-1.

Three different muscles (Longissimus dorsi, Semitendinosus, Extensor carpi ulnaris) of bulls and steers, which represent different parts of the carcass and which have differing properties (function, proportions of fat and connective tissue), were analysed with GC-MS for their contents...

Androgen administration and macrophage behavior in the tissue-implant response - biomed 2011.

Biomedical sciences instrumentation

Butler KR, Benghuzzi H, Tucci M, Puckett A.
PMID: 21525625
Biomed Sci Instrum. 2011;47:228-33.

Macrophages are a critical component in the biocompatibility and function of implantable ceramic materials used in drug delivery applications. As part of the chronic inflammatory response, these cells surround the implant, establishing the tissue-implant interface and produce cytokines critical...

5-alpha-reductase and the development of the human prostate.

Indian journal of urology : IJU : journal of the Urological Society of India

Radmayr C, Lunacek A, Schwentner C, Oswald J, Klocker H, Bartsch G.
PMID: 19468459
Indian J Urol. 2008 Jul;24(3):309-12. doi: 10.4103/0970-1591.42610.

During the 10(th) week of gestation human prostate development is about to start. Androgens are the crucial factors to stimulate the initial interactions between the epithelium and mesenchyme. One of the key events in androgen metabolism is the transformation...

Specific binding of 11-ketotestosterone in an androgen target organ, the kidney of the male three-spined stickleback,Gasterosteus aculeatus.

Fish physiology and biochemistry

Jakobsson S, Mayer I, Schulz RW, Blankenstein MA, Borg B.
PMID: 24194355
Fish Physiol Biochem. 1996 Dec;15(6):459-67. doi: 10.1007/BF01874920.

The kidney of male three-spined stickleback,Gasterosteus aculeatus, hypertrophies during the breeding season and produces a "glue" which is used in the building of the nest. This hypertrophy is androgen dependent, with 11-ketotestosterone (11KT) being more effective than other tested...

Effects of D-004, a lipid extract of the fruit of the Cuban royal palm (Roystonea regia) or the lipidosterolic extract of saw palmetto (Serenoa repens) on the sexual activity in male rats: A controlled, experimental study.

Current therapeutic research, clinical and experimental

Fernández LC, Mas R, Fernández J, Mendoza S, Gámez R, Pardo B.
PMID: 24692784
Curr Ther Res Clin Exp. 2008 Feb;69(1):65-74. doi: 10.1016/j.curtheres.2008.01.002.

BACKGROUND: The etiology of benign prostatic hyperplasia (BPH) is not completely understood, but hormonal changes in aging men seem to be pivotal. Dihydrotestosterone, a potent, active metabolite of testosterone, is formed by the enzymatic action of prostate 5α-reductase and...

Steroids and steroid glucuronides in the ovarian fluid of the African catfish,Clarias gariepinus, between ovulation and oviposition.

Fish physiology and biochemistry

Schoonen WG, Granneman JC, Lambert JG.
PMID: 24226975
Fish Physiol Biochem. 1989 Mar;6(2):91-112. doi: 10.1007/BF01875482.

As part of a series of experiments concerning a possible pheromonal function of steroids and steroid glucuronides excreted by the sex organs of the African catfish,Clarias gariepinus, qualitative and quantitative studies, using GCMS, were carried out to examine the...

Hair-Loss Preventing Effect of Grateloupia elliptica.

Biomolecules & therapeutics

Kang JI, Kim SC, Han SC, Hong HJ, Jeon YJ, Kim B, Koh YS, Yoo ES, Kang HK.
PMID: 24116284
Biomol Ther (Seoul). 2012 Jan;20(1):118-24. doi: 10.4062/biomolther.2012.20.1.118.

This study was conducted to evaluate the effect of Grateloupia elliptica, a seaweed native to Jeju Island, Korea, on the prevention of hair loss. When immortalized rat vibrissa dermal papilla cells were treated with extract of G. elliptica, the...

Showing 25 to 36 of 576 entries