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Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention.

Journal of materials chemistry. B

Mealy JE, Rodell CB, Burdick JA.
PMID: 26693019
J Mater Chem B. 2015 Oct 28;3(40):8010-8019. doi: 10.1039/C5TB00981B. Epub 2015 Sep 18.

Self-assembled and injectable hydrogels have many beneficial properties for the local delivery of therapeutics; however, challenges still exist in the sustained release of small molecules from these highly hydrated networks. Host-guest chemistry between cyclodextrin and adamantane has been used...

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Mealy JE, Rodell CB, Burdick JA. Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. J Mater Chem B. 2015;3(40):8010-8019doi: 10.1039/C5TB00981B.
Mealy, J. E., Rodell, C. B., & Burdick, J. A. (2015). Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. Journal of materials chemistry. B, 3(40), 8010-8019. https://doi.org/10.1039/C5TB00981B
Mealy, Joshua E, et al. "Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention." Journal of materials chemistry. B vol. 3,40 (2015): 8010-8019. doi: https://doi.org/10.1039/C5TB00981B
Mealy JE, Rodell CB, Burdick JA. Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention. J Mater Chem B. 2015 Oct 28;3(40):8010-8019. doi: 10.1039/C5TB00981B. Epub 2015 Sep 18. PMID: 26693019; PMCID: PMC4675358.
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Bleomycin-induced flagellate dermatitis.

Revista brasileira de hematologia e hemoterapia

Mota GD, Penna AM, Soares RC, Baiocchi OC.
PMID: 25031171
Rev Bras Hematol Hemoter. 2014 Jul-Aug;36(4):297-9. doi: 10.1016/j.bjhh.2014.03.001. Epub 2014 Apr 03.

A 29-year-old woman with stage IVB Hodgkin's lymphoma was treated with doxorubicin, bleomycin, vinblastine, and dacarbazine. Two weeks after the first cycle was completed, she developed pruritic, linear erythematous lesions in a flagellate-like pattern on the trunk, neck and...

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Mota GD, Penna AM, Soares RC, et al. Bleomycin-induced flagellate dermatitis. Rev Bras Hematol Hemoter. 2014;36(4):297-9doi: 10.1016/j.bjhh.2014.03.001.
Mota, G. D., Penna, A. M., Soares, R. C., & Baiocchi, O. C. (2014). Bleomycin-induced flagellate dermatitis. Revista brasileira de hematologia e hemoterapia, 36(4), 297-9. https://doi.org/10.1016/j.bjhh.2014.03.001
Mota, Guilherme Devidé, et al. "Bleomycin-induced flagellate dermatitis." Revista brasileira de hematologia e hemoterapia vol. 36,4 (2014): 297-9. doi: https://doi.org/10.1016/j.bjhh.2014.03.001
Mota GD, Penna AM, Soares RC, Baiocchi OC. Bleomycin-induced flagellate dermatitis. Rev Bras Hematol Hemoter. 2014 Jul-Aug;36(4):297-9. doi: 10.1016/j.bjhh.2014.03.001. Epub 2014 Apr 03. PMID: 25031171; PMCID: PMC4207924.
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A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects.

Frontiers in pharmacology

Rauf A, Uddin G, Siddiqui BS, Molnár J, Csonka Á, Ahmad B, Szabó D, Farooq U, Khan A.
PMID: 26732580
Front Pharmacol. 2015 Dec 16;6:293. doi: 10.3389/fphar.2015.00293. eCollection 2015.

Three new dimeric naphthoquinones, 5,4'-dihydroxy-1'-methoxy-6,6'-dimethyl-7,3'-binaphthyl-1,4,5',8'-tetraone (1), 5',8'-dihydroxy-5-methoxy-6,6'-dimethyl-7,3'-binaphthyl-1,4,1',4'-tetraone (2) and 8,5',8'-trihydroxy-6,6'-dimethyl-7,3'-binaphthyl-1,4,1',4'-tetraone (3), were isolated from the roots of Diospyros lotus. Their structures were elucidated by spectroscopic techniques, including 1D and 2D NMR, such as HSQC, HMBS, NOESY, and J-resolved. Compounds...

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Rauf A, Uddin G, Siddiqui BS, et al. A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects. Front Pharmacol. 2015;6:293doi: 10.3389/fphar.2015.00293.
Rauf, A., Uddin, G., Siddiqui, B. S., Molnár, J., Csonka, �. �., Ahmad, B., Szabó, D., Farooq, U., & Khan, A. (2015). A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects. Frontiers in pharmacology, 6293. https://doi.org/10.3389/fphar.2015.00293
Rauf, Abdur, et al. "A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects." Frontiers in pharmacology vol. 6 (2015): 293. doi: https://doi.org/10.3389/fphar.2015.00293
Rauf A, Uddin G, Siddiqui BS, Molnár J, Csonka Á, Ahmad B, Szabó D, Farooq U, Khan A. A Rare Class of New Dimeric Naphthoquinones from Diospyros lotus have Multidrug Reversal and Antiproliferative Effects. Front Pharmacol. 2015 Dec 16;6:293. doi: 10.3389/fphar.2015.00293. eCollection 2015. PMID: 26732580; PMCID: PMC4679852.
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Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An .

Oncology letters

Chiaravalloti A, Pagani M, Cantonetti M, DI Pietro B, Tavolozza M, Travascio L, DI Biagio D, Danieli R, Schillaci O.
PMID: 25621038
Oncol Lett. 2015 Feb;9(2):685-690. doi: 10.3892/ol.2014.2765. Epub 2014 Dec 03.

The aim of the present study was to investigate brain glucose metabolism in patients with Hodgkin disease (HD) after diagnosis and during chemotherapy treatment. Following the administration of first-line doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD) chemotherapy, 74 HD patients...

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Chiaravalloti A, Pagani M, Cantonetti M, et al. Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An . Oncol Lett. 2014;9(2):685-690doi: 10.3892/ol.2014.2765.
Chiaravalloti, A., Pagani, M., Cantonetti, M., DI Pietro, B., Tavolozza, M., Travascio, L., DI Biagio, D., Danieli, R., & Schillaci, O. (2015). Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An . Oncology letters, 9(2), 685-690. https://doi.org/10.3892/ol.2014.2765
Chiaravalloti, Agostino, et al. "Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An ." Oncology letters vol. 9,2 (2015): 685-690. doi: https://doi.org/10.3892/ol.2014.2765
Chiaravalloti A, Pagani M, Cantonetti M, DI Pietro B, Tavolozza M, Travascio L, DI Biagio D, Danieli R, Schillaci O. Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An . Oncol Lett. 2015 Feb;9(2):685-690. doi: 10.3892/ol.2014.2765. Epub 2014 Dec 03. PMID: 25621038; PMCID: PMC4301514.
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Alveolar rhabdomyosarcoma with massive disseminated intravascular coagulopathy treated with systemic chemotherapy.

Korean journal of pediatrics

Yoon BG, Baek HJ, Oh BS, Han DK, Choi YD, Kook H.
PMID: 26770227
Korean J Pediatr. 2015 Dec;58(12):505-8. doi: 10.3345/kjp.2015.58.12.505. Epub 2015 Dec 22.

It is uncommon for pediatric patients with rhabdomyosarcoma to present with clinical and/or laboratory features of disseminated intravascular coagulation (DIC). We report a case of metastatic alveolar rhabdomyosarcoma with severe bleeding because of DIC in a 13-year-old boy. He...

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Yoon BG, Baek HJ, Oh BS, et al. Alveolar rhabdomyosarcoma with massive disseminated intravascular coagulopathy treated with systemic chemotherapy. Korean J Pediatr. 2015;58(12):505-8doi: 10.3345/kjp.2015.58.12.505.
Yoon, B. G., Baek, H. J., Oh, B. S., Han, D. K., Choi, Y. D., & Kook, H. (2015). Alveolar rhabdomyosarcoma with massive disseminated intravascular coagulopathy treated with systemic chemotherapy. Korean journal of pediatrics, 58(12), 505-8. https://doi.org/10.3345/kjp.2015.58.12.505
Yoon, Byung Gyu, et al. "Alveolar rhabdomyosarcoma with massive disseminated intravascular coagulopathy treated with systemic chemotherapy." Korean journal of pediatrics vol. 58,12 (2015): 505-8. doi: https://doi.org/10.3345/kjp.2015.58.12.505
Yoon BG, Baek HJ, Oh BS, Han DK, Choi YD, Kook H. Alveolar rhabdomyosarcoma with massive disseminated intravascular coagulopathy treated with systemic chemotherapy. Korean J Pediatr. 2015 Dec;58(12):505-8. doi: 10.3345/kjp.2015.58.12.505. Epub 2015 Dec 22. PMID: 26770227; PMCID: PMC4705332.
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Quantitative impedimetric monitoring of cell migration under the stimulation of cytokine or anti-cancer drug in a microfluidic chip.

Biomicrofluidics

Liu L, Xiao X, Lei KF, Huang CH.
PMID: 26180566
Biomicrofluidics. 2015 Jun 12;9(3):034109. doi: 10.1063/1.4922488. eCollection 2015 May.

Cell migration is a cellular response and results in various biological processes such as cancer metastasis, that is, the primary cause of death for cancer patients. Quantitative investigation of the correlation between cell migration and extracellular stimulation is essential...

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Liu L, Xiao X, Lei KF, et al. Quantitative impedimetric monitoring of cell migration under the stimulation of cytokine or anti-cancer drug in a microfluidic chip. Biomicrofluidics. 2015;9(3):034109doi: 10.1063/1.4922488.
Liu, L., Xiao, X., Lei, K. F., & Huang, C. H. (2015). Quantitative impedimetric monitoring of cell migration under the stimulation of cytokine or anti-cancer drug in a microfluidic chip. Biomicrofluidics, 9(3), 034109. https://doi.org/10.1063/1.4922488
Liu, Lu, et al. "Quantitative impedimetric monitoring of cell migration under the stimulation of cytokine or anti-cancer drug in a microfluidic chip." Biomicrofluidics vol. 9,3 (2015): 034109. doi: https://doi.org/10.1063/1.4922488
Liu L, Xiao X, Lei KF, Huang CH. Quantitative impedimetric monitoring of cell migration under the stimulation of cytokine or anti-cancer drug in a microfluidic chip. Biomicrofluidics. 2015 Jun 12;9(3):034109. doi: 10.1063/1.4922488. eCollection 2015 May. PMID: 26180566; PMCID: PMC4464059.
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Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy.

EJNMMI research

Rusckowski M, Wang Y, Blankenberg FG, Levashova Z, Backer MV, Backer JM.
PMID: 26780081
EJNMMI Res. 2016 Dec;6(1):4. doi: 10.1186/s13550-016-0163-1. Epub 2016 Jan 16.

BACKGROUND: scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelial growth factor receptors (VEGFR). scVEGF/(177)Lu potential as adjuvant and neoadjuvant anti-angiogenic therapy...

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Rusckowski M, Wang Y, Blankenberg FG, et al. Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI Res. 2016;6(1):4doi: 10.1186/s13550-016-0163-1.
Rusckowski, M., Wang, Y., Blankenberg, F. G., Levashova, Z., Backer, M. V., & Backer, J. M. (2016). Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI research, 6(1), 4. https://doi.org/10.1186/s13550-016-0163-1
Rusckowski, Mary, et al. "Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy." EJNMMI research vol. 6,1 (2016): 4. doi: https://doi.org/10.1186/s13550-016-0163-1
Rusckowski M, Wang Y, Blankenberg FG, Levashova Z, Backer MV, Backer JM. Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy. EJNMMI Res. 2016 Dec;6(1):4. doi: 10.1186/s13550-016-0163-1. Epub 2016 Jan 16. PMID: 26780081; PMCID: PMC4715132.
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A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas.

Sarcoma

Vitfell-Rasmussen J, Judson I, Safwat A, Jones RL, Rossen PB, Lind-Hansen M, Knoblauch P, Krarup-Hansen A.
PMID: 27403082
Sarcoma. 2016;2016:2090271. doi: 10.1155/2016/2090271. Epub 2016 Jun 14.

Background. Belinostat is a novel histone deacetylase inhibitor. Primary Objectives. Maximum tolerated dose (MTD) and dose limiting toxicities (DLTs) of belinostat (Bel) in combination with doxorubicin (Dox) in solid tumours (phase I) and response rate (RR) in soft tissue...

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Vitfell-Rasmussen J, Judson I, Safwat A, et al. A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas. Sarcoma. 2016;2016:2090271doi: 10.1155/2016/2090271.
Vitfell-Rasmussen, J., Judson, I., Safwat, A., Jones, R. L., Rossen, P. B., Lind-Hansen, M., Knoblauch, P., & Krarup-Hansen, A. (2016). A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas. Sarcoma, 20162090271. https://doi.org/10.1155/2016/2090271
Vitfell-Rasmussen, Joanna, et al. "A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas." Sarcoma vol. 2016 (2016): 2090271. doi: https://doi.org/10.1155/2016/2090271
Vitfell-Rasmussen J, Judson I, Safwat A, Jones RL, Rossen PB, Lind-Hansen M, Knoblauch P, Krarup-Hansen A. A Phase I/II Clinical Trial of Belinostat (PXD101) in Combination with Doxorubicin in Patients with Soft Tissue Sarcomas. Sarcoma. 2016;2016:2090271. doi: 10.1155/2016/2090271. Epub 2016 Jun 14. PMID: 27403082; PMCID: PMC4923583.
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A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines.

Cell journal

Haghiralsadat F, Amoabediny G, Sheikhha MH, Forouzanfar T, Helder MN, Zandieh-Doulabi B.
PMID: 28580308
Cell J. 2017;19:55-65. doi: 10.22074/cellj.2017.4502. Epub 2017 May 17.

OBJECTIVE: In this study we prepared a novel formulation of liposomal doxorubicin (L- DOX). The drug dose was optimized by analyses of cellular uptake and cell viability of osteosarcoma (OS) cell lines upon exposure to nanoliposomes that contained varying...

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Haghiralsadat F, Amoabediny G, Sheikhha MH, et al. A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines. Cell J. 2017;19:55-65doi: 10.22074/cellj.2017.4502.
Haghiralsadat, F., Amoabediny, G., Sheikhha, M. H., Forouzanfar, T., Helder, M. N., & Zandieh-Doulabi, B. (2017). A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines. Cell journal, 1955-65. https://doi.org/10.22074/cellj.2017.4502
Haghiralsadat, Fateme, et al. "A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines." Cell journal vol. 19 (2017): 55-65. doi: https://doi.org/10.22074/cellj.2017.4502
Haghiralsadat F, Amoabediny G, Sheikhha MH, Forouzanfar T, Helder MN, Zandieh-Doulabi B. A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines. Cell J. 2017;19:55-65. doi: 10.22074/cellj.2017.4502. Epub 2017 May 17. PMID: 28580308; PMCID: PMC5448319.
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Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance.

Current molecular biology reports

Margaryan NV, Seftor EA, Seftor REB, Hendrix MJC.
PMID: 29152453
Curr Mol Biol Rep. 2017 Sep;3(3):159-164. doi: 10.1007/s40610-017-0067-5. Epub 2017 Jul 10.

PURPOSE OF REVIEW: Cancer is a major public health problem worldwide. In aggressive cancers, which are heterogeneous in nature, there exists a paucity of targetable molecules that can be used to predict outcome and response to therapy in patients,...

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Margaryan NV, Seftor EA, Seftor REB, et al. Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Curr Mol Biol Rep. 2017;3(3):159-164doi: 10.1007/s40610-017-0067-5.
Margaryan, N. V., Seftor, E. A., Seftor, R. E. B., & Hendrix, M. J. C. (2017). Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Current molecular biology reports, 3(3), 159-164. https://doi.org/10.1007/s40610-017-0067-5
Margaryan, Naira V, et al. "Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance." Current molecular biology reports vol. 3,3 (2017): 159-164. doi: https://doi.org/10.1007/s40610-017-0067-5
Margaryan NV, Seftor EA, Seftor REB, Hendrix MJC. Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance. Curr Mol Biol Rep. 2017 Sep;3(3):159-164. doi: 10.1007/s40610-017-0067-5. Epub 2017 Jul 10. PMID: 29152453; PMCID: PMC5687579.
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A Score-Based Approach to .

Diagnostics (Basel, Switzerland)

Bauckneht M, Morbelli S, Fiz F, Ferrarazzo G, Piva R, Nieri A, Sarocchi M, Spallarossa P, Canepari ME, Arboscello E, Bellodi A, Massaia M, Gallamini A, Bruzzi P, Marini C, Sambuceti G.
PMID: 29072629
Diagnostics (Basel). 2017 Oct 26;7(4). doi: 10.3390/diagnostics7040057.

PURPOSE: To verify the capability of METHODS: 36 patients underwent FDG-PET/CT. These patients had shown full remission after DXR-based chemotherapy for Hodgkin's disease (DXR dose: 40-50 mg/m² per cycle), and were retrospectively enrolled. Inclusion criteria implied the presence of...

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Bauckneht M, Morbelli S, Fiz F, et al. A Score-Based Approach to . Diagnostics (Basel). 2017;7(4)doi: 10.3390/diagnostics7040057.
Bauckneht, M., Morbelli, S., Fiz, F., Ferrarazzo, G., Piva, R., Nieri, A., Sarocchi, M., Spallarossa, P., Canepari, M. E., Arboscello, E., Bellodi, A., Massaia, M., Gallamini, A., Bruzzi, P., Marini, C., & Sambuceti, G. (2017). A Score-Based Approach to . Diagnostics (Basel, Switzerland), 7(4), . https://doi.org/10.3390/diagnostics7040057
Bauckneht, Matteo, et al. "A Score-Based Approach to ." Diagnostics (Basel, Switzerland) vol. 7,4 (2017). doi: https://doi.org/10.3390/diagnostics7040057
Bauckneht M, Morbelli S, Fiz F, Ferrarazzo G, Piva R, Nieri A, Sarocchi M, Spallarossa P, Canepari ME, Arboscello E, Bellodi A, Massaia M, Gallamini A, Bruzzi P, Marini C, Sambuceti G. A Score-Based Approach to . Diagnostics (Basel). 2017 Oct 26;7(4). doi: 10.3390/diagnostics7040057. PMID: 29072629; PMCID: PMC5745393.
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Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells.

Research in pharmaceutical sciences

Hendijani F, Javanmard ShH, Rafiee L, Sadeghi-Aliabadi H.
PMID: 26487890
Res Pharm Sci. 2015 Mar-Apr;10(2):134-42.

Multipotent mesenchymal stem cells (MSCs) are recently found to alter the tumor condition. However their exact role in tumor development is not yet fully unraveled. MSCs were established to perform many of their actions through paracrine effect. Thus investigation...

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Hendijani F, Javanmard ShH, Rafiee L, et al. Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells. Res Pharm Sci. 2015;10(2):134-42
Hendijani, F., Javanmard, S. h. H., Rafiee, L., & Sadeghi-Aliabadi, H. (2015). Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells. Research in pharmaceutical sciences, 10(2), 134-42.
Hendijani, F, et al. "Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells." Research in pharmaceutical sciences vol. 10,2 (2015): 134-42.
Hendijani F, Javanmard ShH, Rafiee L, Sadeghi-Aliabadi H. Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells. Res Pharm Sci. 2015 Mar-Apr;10(2):134-42. PMID: 26487890; PMCID: PMC4584452.
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Showing 25 to 36 of 6295 entries