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The influence of the ammonium ion on the stability of ethacrynic acid in aqueous solution.

Journal of pharmaceutical and biomedical analysis

Yarwood RJ, Moore WD, Collett JH.
PMID: 16867506
J Pharm Biomed Anal. 1987;5(4):369-78. doi: 10.1016/0731-7085(87)80043-2.

Investigations by reversed-phase HPLC into the stability of ethacrynic acid in buffered aqueous solutions containing either sodium or ammonium ions showed that the extent of degradation was influenced both by the species and concentration of the cation. A reported...

Ethacrynic Acid Inhibits Sphingosylphosphorylcholine-Induced Keratin 8 Phosphorylation and Reorganization via Transglutaminase-2 Inhibition.

Biomolecules & therapeutics

Byun HJ, Kang KJ, Park MK, Lee HJ, Kang JH, Lee EJ, Kim YR, Kim HJ, Kim YW, Jung KC, Kim SY, Lee CH.
PMID: 24244820
Biomol Ther (Seoul). 2013 Sep 30;21(5):338-42. doi: 10.4062/biomolther.2013.066.

Sphingosylphosphorylcholine (SPC) is significantly increased in the malicious ascites of tumor patients and induces perinuclear reorganization of keratin 8 (K8) filaments in PANC-1 cells. The reorganization contributes to the viscoelasticity of metastatic cancer cells resulting in increased migration. Recently,...

Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes.

Protein & cell

Cui Z, Liu Y, Wan W, Xu Y, Hu Y, Ding M, Dou X, Wang R, Li H, Meng Y, Li W, Jiang W, Li Z, Li Y, Tan M, Ma DK, Ding Y, Liu JO, Luo C, Yu B, Tang Q, Dang Y.
PMID: 32399897
Protein Cell. 2021 Jun;12(6):493-501. doi: 10.1007/s13238-020-00717-7.

No abstract available.

Showing 37 to 39 of 39 entries