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An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock.

The journal of trauma and acute care surgery

Abdou H, Morrison JJ, Edwards J, Patel N, Lang E, Richmond MJ, Elansary N, Gopalakrishnan M, Berman J, Hubbard WJ, Scalea TM, Chaudry IH.
PMID: 34670961
J Trauma Acute Care Surg. 2022 Jan 01;92(1):57-64. doi: 10.1097/TA.0000000000003434.

BACKGROUND: Although 17α-ethinyl estradiol-3-sulfate (EES) reduces mortality in animal models of controlled hemorrhage, its role in a clinically relevant injury model is unknown. We assessed the impact of EES in a swine model of multiple injuries and hemorrhage.METHODS: The...

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Abdou H, Morrison JJ, Edwards J, et al. An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock. J Trauma Acute Care Surg. 2022;92(1):57-64doi: 10.1097/TA.0000000000003434.
Abdou, H., Morrison, J. J., Edwards, J., Patel, N., Lang, E., Richmond, M. J., Elansary, N., Gopalakrishnan, M., Berman, J., Hubbard, W. J., Scalea, T. M., & Chaudry, I. H. (2022). An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock. The journal of trauma and acute care surgery, 92(1), 57-64. https://doi.org/10.1097/TA.0000000000003434
Abdou, Hossam, et al. "An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock." The journal of trauma and acute care surgery vol. 92,1 (2022): 57-64. doi: https://doi.org/10.1097/TA.0000000000003434
Abdou H, Morrison JJ, Edwards J, Patel N, Lang E, Richmond MJ, Elansary N, Gopalakrishnan M, Berman J, Hubbard WJ, Scalea TM, Chaudry IH. An estrogen (17α-ethinyl estradiol-3-sulfate) reduces mortality in a swine model of multiple injuries and hemorrhagic shock. J Trauma Acute Care Surg. 2022 Jan 01;92(1):57-64. doi: 10.1097/TA.0000000000003434. PMID: 34670961.
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Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Kachhawa G, Senthil Kumar KV, Kulshrestha V, Khadgawat R, Mahey R, Bhatla N.
PMID: 34624138
Int J Gynaecol Obstet. 2021 Oct 08; doi: 10.1002/ijgo.13971. Epub 2021 Oct 08.

OBJECTIVE: To compare the effect of myo-inositol and d-chiro-inositol in combination (MI + DCI) with combined hormonal contraceptive (CHC) on menstrual cycle regulation in young Indian women with polycystic ovary syndrome (PCOS).METHODS: Seventy young women with PCOS aged 15-24...

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Kachhawa G, Senthil Kumar KV, Kulshrestha V, et al. Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study. Int J Gynaecol Obstet. 2021;doi: 10.1002/ijgo.13971.
Kachhawa, G., Senthil Kumar, K. V., Kulshrestha, V., Khadgawat, R., Mahey, R., & Bhatla, N. (2021). Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, . https://doi.org/10.1002/ijgo.13971
Kachhawa, Garima, et al. "Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study." International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics vol. (2021). doi: https://doi.org/10.1002/ijgo.13971
Kachhawa G, Senthil Kumar KV, Kulshrestha V, Khadgawat R, Mahey R, Bhatla N. Efficacy of myo-inositol and d-chiro-inositol combination on menstrual cycle regulation and improving insulin resistance in young women with polycystic ovary syndrome: A randomized open-label study. Int J Gynaecol Obstet. 2021 Oct 08; doi: 10.1002/ijgo.13971. Epub 2021 Oct 08. PMID: 34624138.
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Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators.

American journal of reproductive immunology (New York, N.Y. : 1989)

Hughes SM, Pandey U, Johnston C, Marrazzo J, Hladik F, Micks E.
PMID: 33641250
Am J Reprod Immunol. 2021 Aug;86(2):e13412. doi: 10.1111/aji.13412. Epub 2021 Mar 16.

PROBLEM: Changes in sex hormones during the menstrual cycle and contraceptive vaginal ring (CVR) use influence immunity within the female genital tract, but the magnitude of these effects and their anatomical location are unclear.METHOD OF STUDY: In a prospective...

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Hughes SM, Pandey U, Johnston C, et al. Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators. Am J Reprod Immunol. 2021;86(2):e13412doi: 10.1111/aji.13412.
Hughes, S. M., Pandey, U., Johnston, C., Marrazzo, J., Hladik, F., & Micks, E. (2021). Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators. American journal of reproductive immunology (New York, N.Y. : 1989), 86(2), e13412. https://doi.org/10.1111/aji.13412
Hughes, Sean M, et al. "Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators." American journal of reproductive immunology (New York, N.Y. : 1989) vol. 86,2 (2021): e13412. doi: https://doi.org/10.1111/aji.13412
Hughes SM, Pandey U, Johnston C, Marrazzo J, Hladik F, Micks E. Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators. Am J Reprod Immunol. 2021 Aug;86(2):e13412. doi: 10.1111/aji.13412. Epub 2021 Mar 16. PMID: 33641250; PMCID: PMC8298277.
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Efficacy of dienogest vs combined oral contraceptive on pain associated with endometriosis: Randomized clinical trial.

European journal of obstetrics, gynecology, and reproductive biology

El Taha L, Abu Musa A, Khalifeh D, Khalil A, Abbasi S, Nassif J.
PMID: 34826668
Eur J Obstet Gynecol Reprod Biol. 2021 Dec;267:205-212. doi: 10.1016/j.ejogrb.2021.10.029. Epub 2021 Oct 30.

OBJECTIVE: To compare the efficacy of dienogest with the combined oral contraceptive pill (COC) Yasmin for the control of endometriosis-associated pelvic pain.STUDY DESIGN: Seventy women with endometriosis-associated chronic pelvic pain, dysmenorrhoea or both for >6 months were randomized to...

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El Taha L, Abu Musa A, Khalifeh D, et al. Efficacy of dienogest vs combined oral contraceptive on pain associated with endometriosis: Randomized clinical trial. Eur J Obstet Gynecol Reprod Biol. 2021;267:205-212doi: 10.1016/j.ejogrb.2021.10.029.
El Taha, L., Abu Musa, A., Khalifeh, D., Khalil, A., Abbasi, S., & Nassif, J. (2021). Efficacy of dienogest vs combined oral contraceptive on pain associated with endometriosis: Randomized clinical trial. European journal of obstetrics, gynecology, and reproductive biology, 267205-212. https://doi.org/10.1016/j.ejogrb.2021.10.029
El Taha, Lina, et al. "Efficacy of dienogest vs combined oral contraceptive on pain associated with endometriosis: Randomized clinical trial." European journal of obstetrics, gynecology, and reproductive biology vol. 267 (2021): 205-212. doi: https://doi.org/10.1016/j.ejogrb.2021.10.029
El Taha L, Abu Musa A, Khalifeh D, Khalil A, Abbasi S, Nassif J. Efficacy of dienogest vs combined oral contraceptive on pain associated with endometriosis: Randomized clinical trial. Eur J Obstet Gynecol Reprod Biol. 2021 Dec;267:205-212. doi: 10.1016/j.ejogrb.2021.10.029. Epub 2021 Oct 30. PMID: 34826668.
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Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood.

Korean journal of family medicine

Khafagy GM, Shalaby HL, Saad NE, Hasan MD.
PMID: 34871488
Korean J Fam Med. 2021 Nov;42(6):471-476. doi: 10.4082/kjfm.20.0106. Epub 2021 Nov 20.

BACKGROUND: Contraceptive agents are widely used by women of reproductive age, and resulting depression is the most common side effect of this usage. This study aimed to study the effect of monthly injectable combined contraceptives versus that of combined...

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Khafagy GM, Shalaby HL, Saad NE, et al. Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood. Korean J Fam Med. 2021;42(6):471-476doi: 10.4082/kjfm.20.0106.
Khafagy, G. M., Shalaby, H. L., Saad, N. E., & Hasan, M. D. (2021). Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood. Korean journal of family medicine, 42(6), 471-476. https://doi.org/10.4082/kjfm.20.0106
Khafagy, Ghada M, et al. "Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood." Korean journal of family medicine vol. 42,6 (2021): 471-476. doi: https://doi.org/10.4082/kjfm.20.0106
Khafagy GM, Shalaby HL, Saad NE, Hasan MD. Effect of the Monthly Injectable Combined Contraceptives versus Oral Contraceptive Pills on Mood. Korean J Fam Med. 2021 Nov;42(6):471-476. doi: 10.4082/kjfm.20.0106. Epub 2021 Nov 20. PMID: 34871488.
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Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life.

International journal of clinical pharmacology and therapeutics

Sanga M, Vaughan S, Nangosyah J, Scholz V, Fonseca S.
PMID: 34779392
Int J Clin Pharmacol Ther. 2021 Nov 15; doi: 10.5414/CP204034. Epub 2021 Nov 15.

OBJECTIVE: Evaluate bioequivalence, based on norelgestromin (NGMN) and ethinyl estradiol (EE) plasma concentrations, and adhesion of a transdermal contraceptive patch containing a newly sourced adhesive component (test) at end of shelf life (EOSL) vs. the marketed EVRA patch (reference)...

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Sanga M, Vaughan S, Nangosyah J, et al. Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life. Int J Clin Pharmacol Ther. 2021;doi: 10.5414/CP204034.
Sanga, M., Vaughan, S., Nangosyah, J., Scholz, V., & Fonseca, S. (2021). Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life. International journal of clinical pharmacology and therapeutics, . https://doi.org/10.5414/CP204034
Sanga, Madhu, et al. "Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life." International journal of clinical pharmacology and therapeutics vol. (2021). doi: https://doi.org/10.5414/CP204034
Sanga M, Vaughan S, Nangosyah J, Scholz V, Fonseca S. Randomized, double-blind, two-way crossover bioequivalence and adhesion study, in healthy women, of a transdermal contraceptive patch with a newly sourced adhesive component at the end of shelf life vs. the EVRA patch at the beginning of shelf life. Int J Clin Pharmacol Ther. 2021 Nov 15; doi: 10.5414/CP204034. Epub 2021 Nov 15. PMID: 34779392; PMCID: PMC8670371.
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Endocrine disrupting chemicals: strategies to protect present and future generations.

Expert review of endocrinology & metabolism

Vandenberg LN.
PMID: 33973826
Expert Rev Endocrinol Metab. 2021 May;16(3):135-146. doi: 10.1080/17446651.2021.1917991. Epub 2021 May 11.

No abstract available.

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Vandenberg LN. Endocrine disrupting chemicals: strategies to protect present and future generations. Expert Rev Endocrinol Metab. 2021;16(3):135-146doi: 10.1080/17446651.2021.1917991.
Vandenberg, L. N. (2021). Endocrine disrupting chemicals: strategies to protect present and future generations. Expert review of endocrinology & metabolism, 16(3), 135-146. https://doi.org/10.1080/17446651.2021.1917991
Vandenberg, Laura N. "Endocrine disrupting chemicals: strategies to protect present and future generations." Expert review of endocrinology & metabolism vol. 16,3 (2021): 135-146. doi: https://doi.org/10.1080/17446651.2021.1917991
Vandenberg LN. Endocrine disrupting chemicals: strategies to protect present and future generations. Expert Rev Endocrinol Metab. 2021 May;16(3):135-146. doi: 10.1080/17446651.2021.1917991. Epub 2021 May 11. PMID: 33973826.
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Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study.

The journal of sexual medicine

Alcalde AM, Martínez-Zamora MÁ, Gracia M, Ros C, Rius M, Castelo-Branco C, Carmona F.
PMID: 34974988
J Sex Med. 2021 Dec 30; doi: 10.1016/j.jsxm.2021.11.015. Epub 2021 Dec 30.

BACKGROUND: The quality of life of women with deep infiltrating endometriosis (DIE) is impaired and may improve with combined oral contraceptives (COCs).AIM: To compare the overall and sexual quality of life of patients diagnosed with DIE with or without...

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Alcalde AM, Martínez-Zamora MÁ, Gracia M, et al. Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study. J Sex Med. 2021;doi: 10.1016/j.jsxm.2021.11.015.
Alcalde, A. M., Martínez-Zamora, M. �. �., Gracia, M., Ros, C., Rius, M., Castelo-Branco, C., & Carmona, F. (2021). Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study. The journal of sexual medicine, . https://doi.org/10.1016/j.jsxm.2021.11.015
Alcalde, Ana María, et al. "Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study." The journal of sexual medicine vol. (2021). doi: https://doi.org/10.1016/j.jsxm.2021.11.015
Alcalde AM, Martínez-Zamora MÁ, Gracia M, Ros C, Rius M, Castelo-Branco C, Carmona F. Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study. J Sex Med. 2021 Dec 30; doi: 10.1016/j.jsxm.2021.11.015. Epub 2021 Dec 30. PMID: 34974988.
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A retrospective comparison of time to cessation of acute heavy menstrual bleeding in adolescents following two dose regimens of combined oral hormonal therapy.

Journal of pediatric and adolescent gynecology

Roth L, Haley KM, Baldwin MK.
PMID: 34687903
J Pediatr Adolesc Gynecol. 2021 Oct 20; doi: 10.1016/j.jpag.2021.10.003. Epub 2021 Oct 20.

STUDY OBJECTIVE: While multiple hormonal treatment strategies are effective in decreasing heavy menstrual bleeding (HMB) in adolescents, few studies compare relative effectiveness of hormone therapy based on dose.DESIGN: Retrospective chart review SETTING: : Urban tertiary care institution PARTICIPANTS: :...

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Roth L, Haley KM, Baldwin MK. A retrospective comparison of time to cessation of acute heavy menstrual bleeding in adolescents following two dose regimens of combined oral hormonal therapy. J Pediatr Adolesc Gynecol. 2021;doi: 10.1016/j.jpag.2021.10.003.
Roth, L., Haley, K. M., & Baldwin, M. K. (2021). A retrospective comparison of time to cessation of acute heavy menstrual bleeding in adolescents following two dose regimens of combined oral hormonal therapy. Journal of pediatric and adolescent gynecology, . https://doi.org/10.1016/j.jpag.2021.10.003
Roth, Lauryn, et al. "A retrospective comparison of time to cessation of acute heavy menstrual bleeding in adolescents following two dose regimens of combined oral hormonal therapy." Journal of pediatric and adolescent gynecology vol. (2021). doi: https://doi.org/10.1016/j.jpag.2021.10.003
Roth L, Haley KM, Baldwin MK. A retrospective comparison of time to cessation of acute heavy menstrual bleeding in adolescents following two dose regimens of combined oral hormonal therapy. J Pediatr Adolesc Gynecol. 2021 Oct 20; doi: 10.1016/j.jpag.2021.10.003. Epub 2021 Oct 20. PMID: 34687903.
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Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats.

Pathophysiology : the official journal of the International Society for Pathophysiology

Olatunji LA, Michael OS, Adewumi FO, Aiyegboyin IJ, Olatunji VA.
PMID: 21943687
Pathophysiology. 2012 Feb;19(1):29-34. doi: 10.1016/j.pathophys.2011.09.001. Epub 2011 Sep 22.

Women are exposed to sex steroids in several formulations such as oral contraceptives (OCs) and hormone replacement therapies. Estrogen is believed to have cardiometabolic protection effect; but its beneficial effects have recently been queried. The aim of the present...

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Olatunji LA, Michael OS, Adewumi FO, et al. Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats. Pathophysiology. 2011;19(1):29-34doi: 10.1016/j.pathophys.2011.09.001.
Olatunji, L. A., Michael, O. S., Adewumi, F. O., Aiyegboyin, I. J., & Olatunji, V. A. (2012). Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats. Pathophysiology : the official journal of the International Society for Pathophysiology, 19(1), 29-34. https://doi.org/10.1016/j.pathophys.2011.09.001
Olatunji, L A, et al. "Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats." Pathophysiology : the official journal of the International Society for Pathophysiology vol. 19,1 (2012): 29-34. doi: https://doi.org/10.1016/j.pathophys.2011.09.001
Olatunji LA, Michael OS, Adewumi FO, Aiyegboyin IJ, Olatunji VA. Combined estrogen-progestogen but not progestogen-only oral contraceptive alters glucose tolerance and plasma lipid profile in female rats. Pathophysiology. 2012 Feb;19(1):29-34. doi: 10.1016/j.pathophys.2011.09.001. Epub 2011 Sep 22. PMID: 21943687.
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Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study.

Virchows Archiv : an international journal of pathology

Turner BM, Cramer SF, Heller DS, Tavassoli FA.
PMID: 34725735
Virchows Arch. 2021 Nov 02; doi: 10.1007/s00428-021-03225-z. Epub 2021 Nov 02.

Apoplectic leiomyomas-benign uterine leiomyomas with morphologic changes including hemorrhage, hypercellularity, mitotic activity, nuclear atypia, and even necrosis-can be difficult to distinguish from uterine leiomyosarcomas. Apoplectic leiomyomas have been associated with hormonal therapy; however, the relationship between apoplectic leiomyomas, hormones,...

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Turner BM, Cramer SF, Heller DS, et al. Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study. Virchows Arch. 2021;doi: 10.1007/s00428-021-03225-z.
Turner, B. M., Cramer, S. F., Heller, D. S., & Tavassoli, F. A. (2021). Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study. Virchows Archiv : an international journal of pathology, . https://doi.org/10.1007/s00428-021-03225-z
Turner, Bradley M, et al. "Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study." Virchows Archiv : an international journal of pathology vol. (2021). doi: https://doi.org/10.1007/s00428-021-03225-z
Turner BM, Cramer SF, Heller DS, Tavassoli FA. Apoplectic leiomyomas: does ethnicity make a difference? a clinicopathologic study. Virchows Arch. 2021 Nov 02; doi: 10.1007/s00428-021-03225-z. Epub 2021 Nov 02. PMID: 34725735.
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