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Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport.

Drug testing and analysis

Mazzarino M, Comunità F, de la Torre X, Molaioni F, Botrè F.
PMID: 34212529
Drug Test Anal. 2021 Oct;13(10):1712-1726. doi: 10.1002/dta.3121. Epub 2021 Jul 14.

This article reports the results obtained from the investigation of the influence of miconazole administration on the physiological fluctuation of the markers of the steroid profile included in the "steroidal module" of the Athlete Biological Passport. Urines collected from...

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Mazzarino M, Comunità F, de la Torre X, et al. Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport. Drug Test Anal. 2021;13(10):1712-1726doi: 10.1002/dta.3121.
Mazzarino, M., Comunità, F., de la Torre, X., Molaioni, F., & Botrè, F. (2021). Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport. Drug testing and analysis, 13(10), 1712-1726. https://doi.org/10.1002/dta.3121
Mazzarino, Monica, et al. "Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport." Drug testing and analysis vol. 13,10 (2021): 1712-1726. doi: https://doi.org/10.1002/dta.3121
Mazzarino M, Comunità F, de la Torre X, Molaioni F, Botrè F. Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport. Drug Test Anal. 2021 Oct;13(10):1712-1726. doi: 10.1002/dta.3121. Epub 2021 Jul 14. PMID: 34212529; PMCID: PMC8597009.
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Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity.

Frontiers in endocrinology

Sumińska M, Podgórski R, Fichna P, Fichna M.
PMID: 34764940
Front Endocrinol (Lausanne). 2021 Oct 26;12:759971. doi: 10.3389/fendo.2021.759971. eCollection 2021.

Alterations in glucocorticoid metabolism may contribute to the development of obesity and insulin resistance (IR). Obesity in turn affects the androgen balance. The peripheral metabolism of steroids is equally an important determinant of their bioavailability and activity. The aim...

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Sumińska M, Podgórski R, Fichna P, et al. Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Front Endocrinol (Lausanne). 2021;12:759971doi: 10.3389/fendo.2021.759971.
Sumińska, M., Podgórski, R., Fichna, P., & Fichna, M. (2021). Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Frontiers in endocrinology, 12759971. https://doi.org/10.3389/fendo.2021.759971
Sumińska, Marta, et al. "Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity." Frontiers in endocrinology vol. 12 (2021): 759971. doi: https://doi.org/10.3389/fendo.2021.759971
Sumińska M, Podgórski R, Fichna P, Fichna M. Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Front Endocrinol (Lausanne). 2021 Oct 26;12:759971. doi: 10.3389/fendo.2021.759971. eCollection 2021. PMID: 34764940; PMCID: PMC8577858.
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Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity.

Frontiers in endocrinology

Sumińska M, Podgórski R, Fichna P, Fichna M.
PMID: 34764940
Front Endocrinol (Lausanne). 2021 Oct 26;12:759971. doi: 10.3389/fendo.2021.759971. eCollection 2021.

Alterations in glucocorticoid metabolism may contribute to the development of obesity and insulin resistance (IR). Obesity in turn affects the androgen balance. The peripheral metabolism of steroids is equally an important determinant of their bioavailability and activity. The aim...

Cite
Sumińska M, Podgórski R, Fichna P, et al. Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Front Endocrinol (Lausanne). 2021;12:759971doi: 10.3389/fendo.2021.759971.
Sumińska, M., Podgórski, R., Fichna, P., & Fichna, M. (2021). Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Frontiers in endocrinology, 12759971. https://doi.org/10.3389/fendo.2021.759971
Sumińska, Marta, et al. "Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity." Frontiers in endocrinology vol. 12 (2021): 759971. doi: https://doi.org/10.3389/fendo.2021.759971
Sumińska M, Podgórski R, Fichna P, Fichna M. Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity. Front Endocrinol (Lausanne). 2021 Oct 26;12:759971. doi: 10.3389/fendo.2021.759971. eCollection 2021. PMID: 34764940; PMCID: PMC8577858.
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Are the metabolic alterations associated with critical illness related to the hormonal environment?.

Clinical nutrition (Edinburgh, Scotland)

Wilmore DW.
PMID: 16831743
Clin Nutr. 1986 Feb;5(1):9-19. doi: 10.1016/0261-5614(86)90037-3.

The hormonal environment has a direct effect on mediating the catabolic response to critical illness. Administering hormones to normal volunteers simulated many, but not all, of the alterations observed in patients following injury or severe injection. The administration of...

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Wilmore DW. Are the metabolic alterations associated with critical illness related to the hormonal environment?. Clin Nutr. 1986;5(1):9-19doi: 10.1016/0261-5614(86)90037-3.
Wilmore, D. W. (1986). Are the metabolic alterations associated with critical illness related to the hormonal environment?. Clinical nutrition (Edinburgh, Scotland), 5(1), 9-19. https://doi.org/10.1016/0261-5614(86)90037-3
Wilmore, D W. "Are the metabolic alterations associated with critical illness related to the hormonal environment?." Clinical nutrition (Edinburgh, Scotland) vol. 5,1 (1986): 9-19. doi: https://doi.org/10.1016/0261-5614(86)90037-3
Wilmore DW. Are the metabolic alterations associated with critical illness related to the hormonal environment?. Clin Nutr. 1986 Feb;5(1):9-19. doi: 10.1016/0261-5614(86)90037-3. PMID: 16831743.
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5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis.

Drug testing and analysis

Iannella L, Colamonici C, Curcio D, Botrè F, de la Torre X.
PMID: 34318592
Drug Test Anal. 2021 Nov;13(11):1852-1861. doi: 10.1002/dta.3134. Epub 2021 Aug 11.

5α-reductase inhibitors (5-ARIs) are considered by the World Anti-doping Agency as potential confounding factors in evaluating the athlete steroid profile, since they may interfere with the urinary excretion of several diagnostic compounds. We herein investigated 5α-reductase inhibitors from a...

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Iannella L, Colamonici C, Curcio D, et al. 5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis. Drug Test Anal. 2021;13(11):1852-1861doi: 10.1002/dta.3134.
Iannella, L., Colamonici, C., Curcio, D., Botrè, F., & de la Torre, X. (2021). 5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis. Drug testing and analysis, 13(11), 1852-1861. https://doi.org/10.1002/dta.3134
Iannella, Loredana, et al. "5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis." Drug testing and analysis vol. 13,11 (2021): 1852-1861. doi: https://doi.org/10.1002/dta.3134
Iannella L, Colamonici C, Curcio D, Botrè F, de la Torre X. 5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis. Drug Test Anal. 2021 Nov;13(11):1852-1861. doi: 10.1002/dta.3134. Epub 2021 Aug 11. PMID: 34318592.
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Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition.

Journal of the Endocrine Society

Gadot Y, Thörngren JO, Eklund E, Ekström L, Rane A.
PMID: 29942924
J Endocr Soc. 2018 May 23;2(7):597-608. doi: 10.1210/js.2018-00064. eCollection 2018 Jul 01.

OBJECTIVE: To investigate the excretion and conjugation profile of testosterone (T), Epitestosterone (EpiT), and other androgen metabolites in different phases of pregnancy and postpregnancy as a reflection of the "androgenic exposure."DESIGN: Consecutive recruitment of pregnant women.SETTING: Maternity outpatient low-risk...

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Gadot Y, Thörngren JO, Eklund E, et al. Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition. J Endocr Soc. 2018;2(7):597-608doi: 10.1210/js.2018-00064.
Gadot, Y., Thörngren, J. O., Eklund, E., Ekström, L., & Rane, A. (2018). Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition. Journal of the Endocrine Society, 2(7), 597-608. https://doi.org/10.1210/js.2018-00064
Gadot, Yifat, et al. "Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition." Journal of the Endocrine Society vol. 2,7 (2018): 597-608. doi: https://doi.org/10.1210/js.2018-00064
Gadot Y, Thörngren JO, Eklund E, Ekström L, Rane A. Pregnancy-Induced Perturbation of Urinary Androgenic Steroid Disposition. J Endocr Soc. 2018 May 23;2(7):597-608. doi: 10.1210/js.2018-00064. eCollection 2018 Jul 01. PMID: 29942924; PMCID: PMC6007248.
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Influence of Indomethacin on Steroid Metabolism: Endocrine Disruption and Confounding Effects in Urinary Steroid Profiling of Anti-Doping Analyses.

Metabolites

Stoll A, Iannone M, De Gregorio G, Molaioni F, de la Torre X, Botrè F, Parr MK.
PMID: 33202527
Metabolites. 2020 Nov 14;10(11). doi: 10.3390/metabo10110463.

Anabolic androgenic steroids (AAS) are prohibited as doping substances in sports by the World Anti-Doping Agency. Concentrations and concentration ratios of endogenous AAS (steroid profile markers) in urine samples collected from athletes are used to detect their administration. Certain...

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Stoll A, Iannone M, De Gregorio G, et al. Influence of Indomethacin on Steroid Metabolism: Endocrine Disruption and Confounding Effects in Urinary Steroid Profiling of Anti-Doping Analyses. Metabolites. 2020;10(11)doi: 10.3390/metabo10110463.
Stoll, A., Iannone, M., De Gregorio, G., Molaioni, F., de la Torre, X., Botrè, F., & Parr, M. K. (2020). Influence of Indomethacin on Steroid Metabolism: Endocrine Disruption and Confounding Effects in Urinary Steroid Profiling of Anti-Doping Analyses. Metabolites, 10(11), . https://doi.org/10.3390/metabo10110463
Stoll, Anna, et al. "Influence of Indomethacin on Steroid Metabolism: Endocrine Disruption and Confounding Effects in Urinary Steroid Profiling of Anti-Doping Analyses." Metabolites vol. 10,11 (2020). doi: https://doi.org/10.3390/metabo10110463
Stoll A, Iannone M, De Gregorio G, Molaioni F, de la Torre X, Botrè F, Parr MK. Influence of Indomethacin on Steroid Metabolism: Endocrine Disruption and Confounding Effects in Urinary Steroid Profiling of Anti-Doping Analyses. Metabolites. 2020 Nov 14;10(11). doi: 10.3390/metabo10110463. PMID: 33202527; PMCID: PMC7698016.
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Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase II steroid metabolites in urine.

Analytica chimica acta: X

Hernández-Mesa M, Monteau F, Le Bizec B, Dervilly-Pinel G.
PMID: 33117973
Anal Chim Acta X. 2019 Jan 31;1:100006. doi: 10.1016/j.acax.2019.100006. eCollection 2019 Mar.

In recent years, the commercialization of hybrid ion mobility-mass spectrometers and their integration in traditional LC-MS workflows provide new opportunities to extend the current boundaries of targeted and non-targeted analyses. When coupled to LC-MS, ion mobility spectrometry (IMS) provides...

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Hernández-Mesa M, Monteau F, Le Bizec B, et al. Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase II steroid metabolites in urine. Anal Chim Acta X. 2019;1:100006doi: 10.1016/j.acax.2019.100006.
Hernández-Mesa, M., Monteau, F., Le Bizec, B., & Dervilly-Pinel, G. (2019). Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase II steroid metabolites in urine. Analytica chimica acta: X, 1100006. https://doi.org/10.1016/j.acax.2019.100006
Hernández-Mesa, Maykel, et al. "Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase II steroid metabolites in urine." Analytica chimica acta: X vol. 1 (2019): 100006. doi: https://doi.org/10.1016/j.acax.2019.100006
Hernández-Mesa M, Monteau F, Le Bizec B, Dervilly-Pinel G. Potential of ion mobility-mass spectrometry for both targeted and non-targeted analysis of phase II steroid metabolites in urine. Anal Chim Acta X. 2019 Jan 31;1:100006. doi: 10.1016/j.acax.2019.100006. eCollection 2019 Mar. PMID: 33117973; PMCID: PMC7587051.
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Pregnancy greatly affects the steroidal module of the Athlete Biological Passport.

Drug testing and analysis

Mullen J, Gadot Y, Eklund E, Andersson A, J Schulze J, Ericsson M, Lindén Hirschberg A, Rane A, Ekström L.
PMID: 29349906
Drug Test Anal. 2018 Jan 18; doi: 10.1002/dta.2361. Epub 2018 Jan 18.

Concentrations of urinary steroids are measured in anti-doping test programs to detect doping with endogenous steroids. These concentrations are combined into ratios and followed over time in the steroidal module of the Athlete Biological Passport (ABP). The most important...

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Mullen J, Gadot Y, Eklund E, et al. Pregnancy greatly affects the steroidal module of the Athlete Biological Passport. Drug Test Anal. 2018;doi: 10.1002/dta.2361.
Mullen, J., Gadot, Y., Eklund, E., Andersson, A., J Schulze, J., Ericsson, M., Lindén Hirschberg, A., Rane, A., & Ekström, L. (2018). Pregnancy greatly affects the steroidal module of the Athlete Biological Passport. Drug testing and analysis, . https://doi.org/10.1002/dta.2361
Mullen, Jenny, et al. "Pregnancy greatly affects the steroidal module of the Athlete Biological Passport." Drug testing and analysis vol. (2018). doi: https://doi.org/10.1002/dta.2361
Mullen J, Gadot Y, Eklund E, Andersson A, J Schulze J, Ericsson M, Lindén Hirschberg A, Rane A, Ekström L. Pregnancy greatly affects the steroidal module of the Athlete Biological Passport. Drug Test Anal. 2018 Jan 18; doi: 10.1002/dta.2361. Epub 2018 Jan 18. PMID: 29349906.
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Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone.

Drug testing and analysis

Piper T, Haenelt N, Fusshöller G, Geyer H, Thevis M.
PMID: 34648228
Drug Test Anal. 2021 Nov;13(11):1835-1851. doi: 10.1002/dta.3168. Epub 2021 Oct 21.

The testing strategy for the detection of testosterone (T) or T-prohormones is based on the longitudinal evaluation of urinary steroid concentrations accompanied by subsequent isotope ratio mass spectrometry (IRMS)-based confirmation of samples showing atypical concentrations or concentration ratios. In...

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Piper T, Haenelt N, Fusshöller G, et al. Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone. Drug Test Anal. 2021;13(11):1835-1851doi: 10.1002/dta.3168.
Piper, T., Haenelt, N., Fusshöller, G., Geyer, H., & Thevis, M. (2021). Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone. Drug testing and analysis, 13(11), 1835-1851. https://doi.org/10.1002/dta.3168
Piper, Thomas, et al. "Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone." Drug testing and analysis vol. 13,11 (2021): 1835-1851. doi: https://doi.org/10.1002/dta.3168
Piper T, Haenelt N, Fusshöller G, Geyer H, Thevis M. Sensitive detection of testosterone and testosterone prohormone administrations based on urinary concentrations and carbon isotope ratios of androsterone and etiocholanolone. Drug Test Anal. 2021 Nov;13(11):1835-1851. doi: 10.1002/dta.3168. Epub 2021 Oct 21. PMID: 34648228.
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Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia.

International journal of endocrinology and metabolism

Marzuki NS, Idris FP, Kartapradja H, Renata S, Harahap A, Batubara JRL.
PMID: 34149847
Int J Endocrinol Metab. 2021 Apr 18;19(2):e109510. doi: 10.5812/ijem.109510. eCollection 2021 Apr.

BACKGROUND: The 5 Alpha-reductase type 2 deficiency (5ARD2) is an inherited condition, which clinically presents as variable degrees of under virilization in affected 46,XY individuals. In the diagnostic pathway of 5ARD2, the testosterone/dihydrotestosterone (T/DHT) ratio is broadly employed before...

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Marzuki NS, Idris FP, Kartapradja H, et al. Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia. Int J Endocrinol Metab. 2021;19(2):e109510doi: 10.5812/ijem.109510.
Marzuki, N. S., Idris, F. P., Kartapradja, H., Renata, S., Harahap, A., & Batubara, J. R. L. (2021). Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia. International journal of endocrinology and metabolism, 19(2), e109510. https://doi.org/10.5812/ijem.109510
Marzuki, Nanis Sacharina, et al. "Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia." International journal of endocrinology and metabolism vol. 19,2 (2021): e109510. doi: https://doi.org/10.5812/ijem.109510
Marzuki NS, Idris FP, Kartapradja H, Renata S, Harahap A, Batubara JRL. Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia. Int J Endocrinol Metab. 2021 Apr 18;19(2):e109510. doi: 10.5812/ijem.109510. eCollection 2021 Apr. PMID: 34149847; PMCID: PMC8198621.
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Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control.

Steroids

Iannone M, Alberti F, Braganò MC, de la Torre X, Molaioni F, Botrè F.
PMID: 34391799
Steroids. 2021 Oct;174:108900. doi: 10.1016/j.steroids.2021.108900. Epub 2021 Aug 12.

In this work we have investigated the influence of the intake of two synthetic isoflavones, methoxyisoflavone and ipriflavone, on the urinary concentration of endogenous steroids, and on their relative ratios, of doping relevance. Specifically, the concentrations of testosterone (T),...

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Iannone M, Alberti F, Braganò MC, et al. Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control. Steroids. 2021;174:108900doi: 10.1016/j.steroids.2021.108900.
Iannone, M., Alberti, F., Braganò, M. C., de la Torre, X., Molaioni, F., & Botrè, F. (2021). Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control. Steroids, 174108900. https://doi.org/10.1016/j.steroids.2021.108900
Iannone, Michele, et al. "Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control." Steroids vol. 174 (2021): 108900. doi: https://doi.org/10.1016/j.steroids.2021.108900
Iannone M, Alberti F, Braganò MC, de la Torre X, Molaioni F, Botrè F. Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control. Steroids. 2021 Oct;174:108900. doi: 10.1016/j.steroids.2021.108900. Epub 2021 Aug 12. PMID: 34391799.
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Showing 13 to 24 of 25 entries