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Showing 889 to 895 of 895 entries
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Nuclear factor-kappa B (NF-κB) in pathophysiology of Parkinson disease: Diverse patterns and mechanisms contributing to neurodegeneration.

The European journal of neuroscience

Dolatshahi M, Ranjbar Hameghavandi MH, Sabahi M, Rostamkhani S.
PMID: 33884689
Eur J Neurosci. 2021 Apr 21; doi: 10.1111/ejn.15242. Epub 2021 Apr 21.

Parkinson's disease (PD), the most common movement disorder, comprises several pathophysiologic mechanisms including misfolded alpha-synuclein aggregation, inflammation, mitochondrial dysfunction, and synaptic loss. Nuclear Factor-Kappa B (NF-κB), as a key regulator of a myriad of cellular reactions, is shown to...

Asymmetry of the insula-sensorimotor circuit in Parkinson's disease.

The European journal of neuroscience

Goelman G, Dan R, Růžička F, Bezdicek O, Jech R.
PMID: 34449938
Eur J Neurosci. 2021 Sep;54(6):6267-6280. doi: 10.1111/ejn.15432. Epub 2021 Sep 06.

Patients with Parkinson's disease (PD) experience motor and non-motor symptoms, suggesting alterations of the motor and/or limbic system or more probably of their communications. We hypothesized that the communication between the insula (part of the limbic system) and sensorimotor...

Role of the frontal eye field in human pupil and saccade orienting responses.

The European journal of neuroscience

Hsu TY, Hsu YF, Wang HY, Wang CA.
PMID: 33901328
Eur J Neurosci. 2021 Apr 26; doi: 10.1111/ejn.15253. Epub 2021 Apr 26.

The appearance of a salient stimulus evokes a series of orienting responses including saccades and pupil size to prepare the body for appropriate action. The midbrain superior colliculus (SC) that receives critical control signals from the frontal eye field...

Intra-amygdala metaplasticity modulation of fear extinction learning.

The European journal of neuroscience

Saha R, Kriebel M, Anunu R, Volkmer H, Richter-Levin G.
PMID: 33305403
Eur J Neurosci. 2020 Dec 11; doi: 10.1111/ejn.15080. Epub 2020 Dec 11.

The amygdala is a key brain region involved in emotional memory formation. It is also responsible for memory modulation in other brain areas. Under extreme conditions, amygdala modulation may lead to the generation of abnormal plasticity and trauma-related psychopathologies....

Ecological validity in exercise neuroscience research: A systematic investigation.

The European journal of neuroscience

Chang M, Büchel D, Reinecke K, Lehmann T, Baumeister J.
PMID: 34997653
Eur J Neurosci. 2022 Jan 07; doi: 10.1111/ejn.15595. Epub 2022 Jan 07.

The contribution of cortical processes to adaptive motor behaviour is of great interest in the field of exercise neuroscience. Next to established criteria of objectivity, reliability and validity, ecological validity refers to the concerns of whether measurements and behaviour...

Calibrating rhythmic stimulation parameters to individual electroencephalography markers: The consistency of individual alpha frequency in practical lab settings.

The European journal of neuroscience

Janssens SEW, Sack AT, Ten Oever S, de Graaf TA.
PMID: 34363269
Eur J Neurosci. 2021 Aug 07; doi: 10.1111/ejn.15418. Epub 2021 Aug 07.

Rhythmic stimulation can be applied to modulate neuronal oscillations. Such 'entrainment' is optimized when stimulation frequency is individually calibrated based on magneto/encephalography markers. It remains unknown how consistent such individual markers are across days/sessions, within a session, or across...

Microstructural white matter abnormalities in Lesch-Nyhan disease.

The European journal of neuroscience

Del Bene VA, Crawford JL, Gómez-Gastiasoro A, Vannorsdall TD, Buchholz A, Ojeda N, Harris JC, Jinnah HA, Schretlen DJ.
PMID: 34738666
Eur J Neurosci. 2022 Jan;55(1):264-276. doi: 10.1111/ejn.15512. Epub 2021 Dec 06.

Lesch-Nyhan disease is a rare, sex-linked, genetic neurodevelopmental disorder that is characterized by hyperuricemia, dystonia, cognitive impairment and recurrent self-injury. We previously found reduced brain white matter volume in patients with Lesch-Nyhan disease compared with healthy adults using voxel-based...

Showing 889 to 895 of 895 entries