Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 13 to 24 of 200 entries
Sorted by: Best Match Show Resources per page
Fibroblast growth factors 19 and 21 in acute liver damage.

Annals of translational medicine

Shan Z, Alvarez-Sola G, Uriarte I, Arechederra M, Fernández-Barrena MG, Berasain C, Ju C, Avila MA.
PMID: 30069459
Ann Transl Med. 2018 Jun;6(12):257. doi: 10.21037/atm.2018.05.26.

Currently there are very few pharmacological options available to treat acute liver injury. Because its natural exposure to noxious stimuli the liver has developed a strong endogenous hepatoprotective capacity. Indeed, experimental evidence exposed a variety of endogenous hepatic and...

Expression of variant forms of fibroblast growth factor receptor 2 mRNA in human breast carcinomas.

International journal of oncology

Penaultllorca F, Parc P, Coulier F, Bertucci F, Jacquemier J, Birnbaum D.
PMID: 21533503
Int J Oncol. 1997 Jun;10(6):1191-6. doi: 10.3892/ijo.10.6.1191.

FGF (fibroblast growth factors) and FGF receptors may play a role in stroma-epithelium relationships in the mammary gland. Dysregulation of their interactions may be important in mammary carcinogenesis. Isoforms of the FGFR2 receptor, differing in the structure of the...

The effect of fgf-3 int-2 on growth and transformation of mcf-10a normal human mammary epithelial-cells is distinct from fgf-1 and fgf-2.

International journal of oncology

Basolo F, Venesio T, Calvo S, Fiore L, Fontanini G, Ciardiello F, Toniolo A, Liscia D, Merlo G.
PMID: 21567063
Int J Oncol. 1994 Jun;4(6):1365-70. doi: 10.3892/ijo.4.6.1365.

Fibroblast growth factors (FGFs) are related polypeptides with mitogenic activity on cells of mesodermal and neuroectodermal origin. The Fgf-3 gene shares high homology with FGF-2 and its protein product can substitute FGF-2 as a growth factor. Other observations, however,...

Diagnosis and Pathophysiological Mechanisms of Group 3 Hypoxia-Induced Pulmonary Hypertension.

Current treatment options in cardiovascular medicine

Woo KV, Ornitz DM, Singh GK.
PMID: 30903302
Curr Treat Options Cardiovasc Med. 2019 Mar 22;21(3):16. doi: 10.1007/s11936-019-0718-3.

PURPOSE OF REVIEW: Group 3 hypoxia-induced pulmonary hypertension (PH) is an important and increasingly diagnosed condition in both the pediatric and adult population. The majority of pulmonary hypertension studies to date and all three classes of drug therapies were...

The impact of polyphenols on chondrocyte growth and survival: a preliminary report.

Food & nutrition research

Fernández-Arroyo S, Huete-Toral F, Pérez de Lara MJ, de la Luz Cádiz-Gurrea M, Legeai-Mallet L, Micol V, Segura-Carretero A, Joven J, Pintor J.
PMID: 26445212
Food Nutr Res. 2015 Oct 05;59:29311. doi: 10.3402/fnr.v59.29311. eCollection 2015.

BACKGROUND: Imbalances in the functional binding of fibroblast growth factors (FGFs) to their receptors (FGFRs) have consequences for cell proliferation and differentiation that in chondrocytes may lead to degraded cartilage. The toxic, proinflammatory, and oxidative response of cytokines and...

The Effect of Control-released Basic Fibroblast Growth Factor in Wound Healing: Histological Analyses and Clinical Application.

Plastic and reconstructive surgery. Global open

Matsumoto S, Tanaka R, Okada K, Arita K, Hyakusoku H, Miyamoto M, Tabata Y, Mizuno H.
PMID: 25289238
Plast Reconstr Surg Glob Open. 2013 Oct 07;1(6):e44. doi: 10.1097/GOX.0b013e3182a88787. eCollection 2013 Sep.

BACKGROUND: Basic fibroblast growth factors (bFGFs) play a crucial role in wound healing by promoting fibroblast proliferation and neovascularization. However, drawback of bFGF is short half-life in free form. Gelatin has a capability of sustaining growth factors, which are...

Fibroblast growth factor-4 maintains cellular viability while enhancing osteogenic differentiation of stem cell spheroids in part by regulating RUNX2 and BGLAP expression.

Experimental and therapeutic medicine

Son J, Tae JY, Min SK, Ko Y, Park JB, Sulistyaningrum SD.
PMID: 32782511
Exp Ther Med. 2020 Sep;20(3):2013-2020. doi: 10.3892/etm.2020.8951. Epub 2020 Jun 26.

Fibroblast growth factors (FGFs) are growth factors that were initially identified as proteins that stimulate fibroblast proliferation. The aim of the present study was to examine the effects of FGF-4 on the morphology, cellular viability and osteogenic differentiation of...

Regulation of Renal Differentiation by Trophic Factors.

Frontiers in physiology

Kurtzeborn K, Cebrian C, Kuure S.
PMID: 30483151
Front Physiol. 2018 Nov 12;9:1588. doi: 10.3389/fphys.2018.01588. eCollection 2018.

Classically, trophic factors are considered as proteins which support neurons in their growth, survival, and differentiation. However, most neurotrophic factors also have important functions outside of the nervous system. Especially essential renal growth and differentiation regulators are glial cell...

The Effect of Fibroblast Growth Factors in Grafted Fascia into the Vocal Fold of Rabbits.

International archives of otorhinolaryngology

Carvalho EGB, Machado-Júnior AJ, Pauna HF, Nicola EMD, Altemani AMAM, Crespo AN.
PMID: 30647785
Int Arch Otorhinolaryngol. 2019 Jan;23(1):60-64. doi: 10.1055/s-0038-1661399. Epub 2018 Jul 05.

No abstract available.

FGF2 and FGF10 expression patterns in the epidermis and mesenchyme during homeotic transformation of tail into hindlimbs in frog tadpoles.

Acta histochemica

Hota J, Mahapatra PK.
PMID: 34968793
Acta Histochem. 2021 Dec 27;124(1):151836. doi: 10.1016/j.acthis.2021.151836. Epub 2021 Dec 27.

Limbs are trunk quintessential in tetrapods. Their development relies on the Retinoic acid (RA) gradient in association with the Fibroblast Growth Factors (FGFs). The role of various FGFs have been probed extensively and confirmed during the induction of ectopic...

Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy.

Circulation

Yuan P, Cheedipudi SM, Rouhi L, Fan S, Simon L, Zhao Z, Hong K, Gurha P, Marian AJ.
PMID: 33726497
Circulation. 2021 Jun;143(22):2169-2187. doi: 10.1161/CIRCULATIONAHA.120.052928. Epub 2021 Mar 17.

BACKGROUND: Arrhythmogenic cardiomyopathy (ACM) manifests with sudden death, arrhythmias, heart failure, apoptosis, and myocardial fibro-adipogenesis. The phenotype typically starts at the epicardium and advances transmurally. Mutations in genes encoding desmosome proteins, including DSP (desmoplakin), are major causes of ACM.METHODS:...

FGF2 and FGF10 expression patterns in the epidermis and mesenchyme during homeotic transformation of tail into hindlimbs in frog tadpoles.

Acta histochemica

Hota J, Mahapatra PK.
PMID: 34968793
Acta Histochem. 2021 Dec 28;124(1):151836. doi: 10.1016/j.acthis.2021.151836. Epub 2021 Dec 28.

Limbs are trunk quintessential in tetrapods. Their development relies on the Retinoic acid (RA) gradient in association with the Fibroblast Growth Factors (FGFs). The role of various FGFs have been probed extensively and confirmed during the induction of ectopic...

Showing 13 to 24 of 200 entries