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Showing 6253 to 6255 of 6255 entries
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In-vitro Cytotoxicity and Aromatase Inhibitory Activity of Flavonoids: Synthesis, Molecular Docking and In-silico ADME Prediction.

Anti-cancer agents in medicinal chemistry

Shah U, Patel S, Patel M, Jain N, Pandey N, Chauhan A, Patel A, Patel S.
PMID: 34455966
Anticancer Agents Med Chem. 2021 Aug 26; doi: 10.2174/1871520621666210827104406. Epub 2021 Aug 26.

BACKGROUND: Many natural and synthetic flavonoids have been studied and documented by inhibiting aromatase enzymes for their anti-cancer activity against breast carcinoma. The aromatase enzyme is a possible target for the estrogen's positive breast cancer receptor.OBJECTIVE: Hence, a series...

Flavonoids and proanthocyanidins-rich fractions from Eugenia dysenterica fruits and leaves inhibit the formation of advanced glycation end-products and the activities of α-amylase and α-glucosidase.

Journal of ethnopharmacology

Justino AB, Guerra Silva HC, Franco RR, de Oliveira Cavalcante Pimentel I, Silva NF, Saraiva AL, Espindola FS.
PMID: 34890729
J Ethnopharmacol. 2021 Dec 08;285:114902. doi: 10.1016/j.jep.2021.114902. Epub 2021 Dec 08.

ETHNOPHARMACOLOGICAL RELEVANCE: Different parts of Eugenia dysenterica have been popularly used in Brazil for treating diabetes mellitus and its complications. The present study aimed to screen extracts from E. dysenterica fruit pulp, peel, seed and leaf for carbohydrate digestive...

Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis .

Journal of advanced research

Zhang Q, Liu J, Duan H, Li R, Peng W, Wu C.
PMID: 35024180
J Adv Res. 2021 Jul 06;34:43-63. doi: 10.1016/j.jare.2021.06.023. eCollection 2021 Dec.

INTRODUCTION: Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury.OBJECTIVES: This paper aimed to summarized the natural monomers/extracts that...

Showing 6253 to 6255 of 6255 entries