Current neurovascular research
Maiese K.
PMID: 33397266
Curr Neurovasc Res. 2021;18(1):134-149. doi: 10.2174/1567202617999210104220334.
Neurodegenerative disorders impact more than one billion individuals worldwide and are intimately tied to metabolic disease that can affect another nine hundred individuals throughout the globe. Nicotinamide is a critical agent that may offer fruitful prospects for neurodegenerative diseases...
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Maiese K. Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders. Curr Neurovasc Res. 2021;18(1):134-149doi: 10.2174/1567202617999210104220334.
Maiese, K. (2021). Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders. Current neurovascular research, 18(1), 134-149. https://doi.org/10.2174/1567202617999210104220334
Maiese, Kenneth. "Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders." Current neurovascular research vol. 18,1 (2021): 134-149. doi: https://doi.org/10.2174/1567202617999210104220334
Maiese K. Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders. Curr Neurovasc Res. 2021;18(1):134-149. doi: 10.2174/1567202617999210104220334. PMID: 33397266; PMCID: PMC8254823.
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NPJ systems biology and applications
Barberis M.
PMID: 34903735
NPJ Syst Biol Appl. 2021 Dec 13;7(1):48. doi: 10.1038/s41540-021-00201-w.
Networks of interacting molecules organize topology, amount, and timing of biological functions. Systems biology concepts required to pin down 'network motifs' or 'design principles' for time-dependent processes have been developed for the cell division cycle, through integration of predictive...
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Barberis M. Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ Syst Biol Appl. 2021;7(1):48doi: 10.1038/s41540-021-00201-w.
Barberis, M. (2021). Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ systems biology and applications, 7(1), 48. https://doi.org/10.1038/s41540-021-00201-w
Barberis, Matteo. "Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast." NPJ systems biology and applications vol. 7,1 (2021): 48. doi: https://doi.org/10.1038/s41540-021-00201-w
Barberis M. Cyclin/Forkhead-mediated coordination of cyclin waves: an autonomous oscillator rationalizing the quantitative model of Cdk control for budding yeast. NPJ Syst Biol Appl. 2021 Dec 13;7(1):48. doi: 10.1038/s41540-021-00201-w. PMID: 34903735; PMCID: PMC8668886.
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Aging and disease
Rollo CD.
PMID: 22396860
Aging Dis. 2010 Oct;1(2):105-38. Epub 2010 Sep 10.
A temporal framework linking circadian rhythms and clocks to aging rates identifies a specific window of target of rapamycin (TOR) signaling associated with growth hormone (GH) and insulin-like growth factor (IGF-1) (largely exclusive of insulin) in early sleep. IGF-1...
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Rollo CD. Aging and the Mammalian regulatory triumvirate. Aging Dis. 2010;1(2):105-38
Rollo, C. D. (2010). Aging and the Mammalian regulatory triumvirate. Aging and disease, 1(2), 105-38.
Rollo, C David. "Aging and the Mammalian regulatory triumvirate." Aging and disease vol. 1,2 (2010): 105-38.
Rollo CD. Aging and the Mammalian regulatory triumvirate. Aging Dis. 2010 Oct;1(2):105-38. Epub 2010 Sep 10. PMID: 22396860; PMCID: PMC3295031.
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Neural regeneration research
Maiese K.
PMID: 32985464
Neural Regen Res. 2021 Mar;16(3):448-455. doi: 10.4103/1673-5374.291382.
The global increase in lifespan noted not only in developed nations, but also in large developing countries parallels an observed increase in a significant number of non-communicable diseases, most notable neurodegenerative disorders. Neurodegenerative disorders present a number of challenges...
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Maiese K. Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1. Neural Regen Res. 2021;16(3):448-455doi: 10.4103/1673-5374.291382.
Maiese, K. (2021). Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1. Neural regeneration research, 16(3), 448-455. https://doi.org/10.4103/1673-5374.291382
Maiese, Kenneth. "Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1." Neural regeneration research vol. 16,3 (2021): 448-455. doi: https://doi.org/10.4103/1673-5374.291382
Maiese K. Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1. Neural Regen Res. 2021 Mar;16(3):448-455. doi: 10.4103/1673-5374.291382. PMID: 32985464; PMCID: PMC7996023.
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Clinical epigenetics
Karlic H, Varga F.
PMID: 22704269
Clin Epigenetics. 2011 Apr;2(1):55-61. doi: 10.1007/s13148-011-0021-y. Epub 2011 Feb 08.
The bioactive vitamin D (VD) metabolite, 1,25-dihydroxyvitamin D(3) regulates essential pathways of cellular metabolism and differentiation via its nuclear receptor (VDR). Molecular mechanisms which are known to play key roles in aging and cancer are mediated by complex processes...
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Karlic H, Varga F. Impact of vitamin D metabolism on clinical epigenetics. Clin Epigenetics. 2011;2(1):55-61doi: 10.1007/s13148-011-0021-y.
Karlic, H., & Varga, F. (2011). Impact of vitamin D metabolism on clinical epigenetics. Clinical epigenetics, 2(1), 55-61. https://doi.org/10.1007/s13148-011-0021-y
Karlic, Heidrun, and Varga, Franz. "Impact of vitamin D metabolism on clinical epigenetics." Clinical epigenetics vol. 2,1 (2011): 55-61. doi: https://doi.org/10.1007/s13148-011-0021-y
Karlic H, Varga F. Impact of vitamin D metabolism on clinical epigenetics. Clin Epigenetics. 2011 Apr;2(1):55-61. doi: 10.1007/s13148-011-0021-y. Epub 2011 Feb 08. PMID: 22704269; PMCID: PMC3365599.
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Journal of translational science
Maiese K.
PMID: 27200181
J Transl Sci. 2016;2(3):185-187. doi: 10.15761/JTS.1000138. Epub 2016 Apr 28.
Oxidative stress and the generation of reactive oxygen species (ROS) can lead to mitochondrial dysfunction, DNA damage, protein misfolding, programmed cell death with apoptosis and autophagy, and the promotion of aging -dependent processes. Mitochondria control the processing of redox...
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Maiese K. The bright side of reactive oxygen species: lifespan extension without cellular demise. J Transl Sci. 2016;2(3):185-187doi: 10.15761/JTS.1000138.
Maiese, K. (2016). The bright side of reactive oxygen species: lifespan extension without cellular demise. Journal of translational science, 2(3), 185-187. https://doi.org/10.15761/JTS.1000138
Maiese, Kenneth. "The bright side of reactive oxygen species: lifespan extension without cellular demise." Journal of translational science vol. 2,3 (2016): 185-187. doi: https://doi.org/10.15761/JTS.1000138
Maiese K. The bright side of reactive oxygen species: lifespan extension without cellular demise. J Transl Sci. 2016;2(3):185-187. doi: 10.15761/JTS.1000138. Epub 2016 Apr 28. PMID: 27200181; PMCID: PMC4869880.
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Frontiers in molecular neuroscience
Mendoza E, Scharff C.
PMID: 28507505
Front Mol Neurosci. 2017 May 01;10:112. doi: 10.3389/fnmol.2017.00112. eCollection 2017.
The Forkhead transcription factor FOXP2 is implicated in speech perception and production. The avian homolog, FoxP2 contributes to song learning and production in birds. In human cell lines, transcriptional activity of FOXP2 requires homo-dimerization or dimerization with paralogs FOXP1...
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Mendoza E, Scharff C. Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, . Front Mol Neurosci. 2017;10:112doi: 10.3389/fnmol.2017.00112.
Mendoza, E., & Scharff, C. (2017). Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, . Frontiers in molecular neuroscience, 10112. https://doi.org/10.3389/fnmol.2017.00112
Mendoza, Ezequiel, and Scharff, Constance. "Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, ." Frontiers in molecular neuroscience vol. 10 (2017): 112. doi: https://doi.org/10.3389/fnmol.2017.00112
Mendoza E, Scharff C. Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, . Front Mol Neurosci. 2017 May 01;10:112. doi: 10.3389/fnmol.2017.00112. eCollection 2017. PMID: 28507505; PMCID: PMC5410569.
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Frontiers in bioscience (Landmark edition)
Maiese K.
PMID: 26549969
Front Biosci (Landmark Ed). 2016 Jan;21(3):561-596. doi: 10.2741/4408.
Globally, greater than 30 million individuals are afflicted with disorders of the nervous system accompanied by tens of thousands of new cases annually with limited, if any, treatment options. Erythropoietin (EPO) offers an exciting and novel therapeutic strategy to...
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Maiese K. Regeneration in the nervous system with erythropoietin. Front Biosci (Landmark Ed). 2016;21(3):561-596doi: 10.2741/4408.
Maiese, K. (2016). Regeneration in the nervous system with erythropoietin. Frontiers in bioscience (Landmark edition), 21(3), 561-596. https://doi.org/10.2741/4408
Maiese, Kenneth. "Regeneration in the nervous system with erythropoietin." Frontiers in bioscience (Landmark edition) vol. 21,3 (2016): 561-596. doi: https://doi.org/10.2741/4408
Maiese K. Regeneration in the nervous system with erythropoietin. Front Biosci (Landmark Ed). 2016 Jan;21(3):561-596. doi: 10.2741/4408. PMID: 26549969; PMCID: PMC4632844.
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Frontiers in cell and developmental biology
Ruiz-Losada M, Pérez-Reyes C, Estella C.
PMID: 34409041
Front Cell Dev Biol. 2021 Aug 02;9:723927. doi: 10.3389/fcell.2021.723927. eCollection 2021.
Appendage development requires the coordinated function of signaling pathways and transcription factors to pattern the leg along the three main axes: the antero-posterior (AP), proximo-distal (PD), and dorso-ventral (DV). The
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Ruiz-Losada M, Pérez-Reyes C, Estella C. Role of the Forkhead Transcription Factors Fd4 and Fd5 During . Front Cell Dev Biol. 2021;9:723927doi: 10.3389/fcell.2021.723927.
Ruiz-Losada, M., Pérez-Reyes, C., & Estella, C. (2021). Role of the Forkhead Transcription Factors Fd4 and Fd5 During . Frontiers in cell and developmental biology, 9723927. https://doi.org/10.3389/fcell.2021.723927
Ruiz-Losada, Mireya, et al. "Role of the Forkhead Transcription Factors Fd4 and Fd5 During ." Frontiers in cell and developmental biology vol. 9 (2021): 723927. doi: https://doi.org/10.3389/fcell.2021.723927
Ruiz-Losada M, Pérez-Reyes C, Estella C. Role of the Forkhead Transcription Factors Fd4 and Fd5 During . Front Cell Dev Biol. 2021 Aug 02;9:723927. doi: 10.3389/fcell.2021.723927. eCollection 2021. PMID: 34409041; PMCID: PMC8365472.
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Diabetes, metabolic syndrome and obesity : targets and therapy
Tomkin GH, Owens D.
PMID: 28814891
Diabetes Metab Syndr Obes. 2017 Jul 28;10:333-343. doi: 10.2147/DMSO.S115855. eCollection 2017.
Premature atherosclerosis in diabetes accounts for much of the decreased life span. New treatments have reduced this risk considerably. This review explores the relationship among the disturbances in glucose, lipid, and bile salt metabolic pathways that occur in diabetes....
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Tomkin GH, Owens D. Diabetes and dyslipidemia: characterizing lipoprotein metabolism. Diabetes Metab Syndr Obes. 2017;10:333-343doi: 10.2147/DMSO.S115855.
Tomkin, G. H., & Owens, D. (2017). Diabetes and dyslipidemia: characterizing lipoprotein metabolism. Diabetes, metabolic syndrome and obesity : targets and therapy, 10333-343. https://doi.org/10.2147/DMSO.S115855
Tomkin, G H, and Owens, D. "Diabetes and dyslipidemia: characterizing lipoprotein metabolism." Diabetes, metabolic syndrome and obesity : targets and therapy vol. 10 (2017): 333-343. doi: https://doi.org/10.2147/DMSO.S115855
Tomkin GH, Owens D. Diabetes and dyslipidemia: characterizing lipoprotein metabolism. Diabetes Metab Syndr Obes. 2017 Jul 28;10:333-343. doi: 10.2147/DMSO.S115855. eCollection 2017. PMID: 28814891; PMCID: PMC5546776.
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Journal of translational science
Maiese K.
PMID: 27390624
J Transl Sci. 2016 Jul;2(4):241-247. doi: 10.15761/JTS.1000146. Epub 2016 Jun 14.
Life expectancy of individuals in both developed and undeveloped nations continues to rise at an unprecedented rate. Coupled to this increase in longevity for individuals is the rise in the incidence of chronic neurodegenerative disorders that includes Alzheimer's disease...
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Maiese K. Forkhead transcription factors: new considerations for alzheimer's disease and dementia. J Transl Sci. 2016;2(4):241-247doi: 10.15761/JTS.1000146.
Maiese, K. (2016). Forkhead transcription factors: new considerations for alzheimer's disease and dementia. Journal of translational science, 2(4), 241-247. https://doi.org/10.15761/JTS.1000146
Maiese, Kenneth. "Forkhead transcription factors: new considerations for alzheimer's disease and dementia." Journal of translational science vol. 2,4 (2016): 241-247. doi: https://doi.org/10.15761/JTS.1000146
Maiese K. Forkhead transcription factors: new considerations for alzheimer's disease and dementia. J Transl Sci. 2016 Jul;2(4):241-247. doi: 10.15761/JTS.1000146. Epub 2016 Jun 14. PMID: 27390624; PMCID: PMC4932907.
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Journal of translational science
Maiese K.
PMID: 27642518
J Transl Sci. 2016;2(6):327-329. doi: 10.15761/jts.1000158. Epub 2016 Aug 31.
Circular ribonucleic acids (circRNAs) are non-coding RNAs of approximately 100 nucleotides in length with thousands of members in mammalian cells. The presence of circRNAs is believed to be even greater than that of messenger RNAs. Identification of circRNAs occurred...
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Maiese K. Disease onset and aging in the world of circular RNAs. J Transl Sci. 2016;2(6):327-329doi: 10.15761/jts.1000158.
Maiese, K. (2016). Disease onset and aging in the world of circular RNAs. Journal of translational science, 2(6), 327-329. https://doi.org/10.15761/jts.1000158
Maiese, Kenneth. "Disease onset and aging in the world of circular RNAs." Journal of translational science vol. 2,6 (2016): 327-329. doi: https://doi.org/10.15761/jts.1000158
Maiese K. Disease onset and aging in the world of circular RNAs. J Transl Sci. 2016;2(6):327-329. doi: 10.15761/jts.1000158. Epub 2016 Aug 31. PMID: 27642518; PMCID: PMC5026119.
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