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Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway.

International immunopharmacology

Ruan Y, Ling J, Ye F, Cheng N, Wu F, Tang Z, Cheng X, Liu H.
PMID: 34844873
Int Immunopharmacol. 2021 Dec;101:108364. doi: 10.1016/j.intimp.2021.108364. Epub 2021 Nov 26.

BACKGROUND: Treatment of chronic inflammatory pain remains a major goal in the clinic. It is thus of prime importance to characterize inherent pathophysiological pathways to design new therapeutic strategies and analgesics for pain management. Paeoniflorin (PF), a monoterpenoid glycoside...

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Ruan Y, Ling J, Ye F, et al. Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway. Int Immunopharmacol. 2021;101:108364doi: 10.1016/j.intimp.2021.108364.
Ruan, Y., Ling, J., Ye, F., Cheng, N., Wu, F., Tang, Z., Cheng, X., & Liu, H. (2021). Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway. International immunopharmacology, 101108364. https://doi.org/10.1016/j.intimp.2021.108364
Ruan, Yonglan, et al. "Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway." International immunopharmacology vol. 101 (2021): 108364. doi: https://doi.org/10.1016/j.intimp.2021.108364
Ruan Y, Ling J, Ye F, Cheng N, Wu F, Tang Z, Cheng X, Liu H. Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway. Int Immunopharmacol. 2021 Dec;101:108364. doi: 10.1016/j.intimp.2021.108364. Epub 2021 Nov 26. PMID: 34844873.
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TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice.

Cellular and molecular neurobiology

Lu Y, Cao DL, Ma LJ, Gao YJ.
PMID: 33694132
Cell Mol Neurobiol. 2021 Mar 10; doi: 10.1007/s10571-021-01045-y. Epub 2021 Mar 10.

Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been reported to be expressed in spinal astrocytes and is involved in neuropathic pain. In this study, we investigated the role and mechanism of TRAF6 in complete Freund's adjuvant (CFA)-evoked chronic...

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Lu Y, Cao DL, Ma LJ, et al. TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice. Cell Mol Neurobiol. 2021;doi: 10.1007/s10571-021-01045-y.
Lu, Y., Cao, D. L., Ma, L. J., & Gao, Y. J. (2021). TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice. Cellular and molecular neurobiology, . https://doi.org/10.1007/s10571-021-01045-y
Lu, Ying, et al. "TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice." Cellular and molecular neurobiology vol. (2021). doi: https://doi.org/10.1007/s10571-021-01045-y
Lu Y, Cao DL, Ma LJ, Gao YJ. TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice. Cell Mol Neurobiol. 2021 Mar 10; doi: 10.1007/s10571-021-01045-y. Epub 2021 Mar 10. PMID: 33694132.
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Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation.

Neuromodulation : journal of the International Neuromodulation Society

Huang RY, Poree L, Ho KY, Tsai SY, Liu YC, Tan PH, Wen YR.
PMID: 32558126
Neuromodulation. 2021 Dec;24(8):1458-1466. doi: 10.1111/ner.13169. Epub 2020 Jun 17.

OBJECTIVES: Pulsed radiofrequency (PRF) stimulation is widely used for intractable pain; however, there is no consensus on treatment protocols and appropriate types of pain. We compared effectiveness of bipolar and unipolar PRF on neuropathic or inflammatory pains, and of...

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Huang RY, Poree L, Ho KY, et al. Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation. 2020;24(8):1458-1466doi: 10.1111/ner.13169.
Huang, R. Y., Poree, L., Ho, K. Y., Tsai, S. Y., Liu, Y. C., Tan, P. H., & Wen, Y. R. (2021). Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation : journal of the International Neuromodulation Society, 24(8), 1458-1466. https://doi.org/10.1111/ner.13169
Huang, Ren-Yu, et al. "Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation." Neuromodulation : journal of the International Neuromodulation Society vol. 24,8 (2021): 1458-1466. doi: https://doi.org/10.1111/ner.13169
Huang RY, Poree L, Ho KY, Tsai SY, Liu YC, Tan PH, Wen YR. Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation. Neuromodulation. 2021 Dec;24(8):1458-1466. doi: 10.1111/ner.13169. Epub 2020 Jun 17. PMID: 32558126.
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Complete Freund's adjuvant-induced protein dysregulation correlated with mirror image pain as assessed by quantitative proteomics of the mouse spinal cord.

Biochemical and biophysical research communications

Ma Q, Chen X, Sun J, Wang L, Jiang W, Zhang X, Chen S.
PMID: 34883286
Biochem Biophys Res Commun. 2021 Nov 12;589:23-28. doi: 10.1016/j.bbrc.2021.11.032. Epub 2021 Nov 12.

Inflammation or trauma occurring on one side of the body can cause pathological pain on the contralateral noninjured side in a phenomenon called mirror-image pain (MIP). Although some potential mechanisms involved in MIP have been reported, including those involving...

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Ma Q, Chen X, Sun J, et al. Complete Freund's adjuvant-induced protein dysregulation correlated with mirror image pain as assessed by quantitative proteomics of the mouse spinal cord. Biochem Biophys Res Commun. 2021;589:23-28doi: 10.1016/j.bbrc.2021.11.032.
Ma, Q., Chen, X., Sun, J., Wang, L., Jiang, W., Zhang, X., & Chen, S. (2021). Complete Freund's adjuvant-induced protein dysregulation correlated with mirror image pain as assessed by quantitative proteomics of the mouse spinal cord. Biochemical and biophysical research communications, 58923-28. https://doi.org/10.1016/j.bbrc.2021.11.032
Ma, Quan, et al. "Complete Freund's adjuvant-induced protein dysregulation correlated with mirror image pain as assessed by quantitative proteomics of the mouse spinal cord." Biochemical and biophysical research communications vol. 589 (2021): 23-28. doi: https://doi.org/10.1016/j.bbrc.2021.11.032
Ma Q, Chen X, Sun J, Wang L, Jiang W, Zhang X, Chen S. Complete Freund's adjuvant-induced protein dysregulation correlated with mirror image pain as assessed by quantitative proteomics of the mouse spinal cord. Biochem Biophys Res Commun. 2021 Nov 12;589:23-28. doi: 10.1016/j.bbrc.2021.11.032. Epub 2021 Nov 12. PMID: 34883286.
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Adverse effect of rheumatoid arthritis on male Wistar rat's fertility: protective role of Costus extract.

Environmental science and pollution research international

Kamel S, Tag HM, Ebeid H, Khaled HE, Almallah AA, El-Naggar MS.
PMID: 34403061
Environ Sci Pollut Res Int. 2021 Aug 17; doi: 10.1007/s11356-021-16001-y. Epub 2021 Aug 17.

Rheumatoid arthritis (RA) is a systemic autoimmune complaint. Advanced treatments resort to the traditional herbal therapy. The aim of this study is to assess the protective effect of Costus extract on the fertility of male rats with Freund's adjuvant-induced...

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Kamel S, Tag HM, Ebeid H, et al. Adverse effect of rheumatoid arthritis on male Wistar rat's fertility: protective role of Costus extract. Environ Sci Pollut Res Int. 2021;doi: 10.1007/s11356-021-16001-y.
Kamel, S., Tag, H. M., Ebeid, H., Khaled, H. E., Almallah, A. A., & El-Naggar, M. S. (2021). Adverse effect of rheumatoid arthritis on male Wistar rat's fertility: protective role of Costus extract. Environmental science and pollution research international, . https://doi.org/10.1007/s11356-021-16001-y
Kamel, Samar, et al. "Adverse effect of rheumatoid arthritis on male Wistar rat's fertility: protective role of Costus extract." Environmental science and pollution research international vol. (2021). doi: https://doi.org/10.1007/s11356-021-16001-y
Kamel S, Tag HM, Ebeid H, Khaled HE, Almallah AA, El-Naggar MS. Adverse effect of rheumatoid arthritis on male Wistar rat's fertility: protective role of Costus extract. Environ Sci Pollut Res Int. 2021 Aug 17; doi: 10.1007/s11356-021-16001-y. Epub 2021 Aug 17. PMID: 34403061.
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Showing 457 to 461 of 461 entries