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Showing 25 to 36 of 3295 entries
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GPla Polymorphisms Are Associated with Outcomes in Patients at High Cardiovascular Risk.

Frontiers in cardiovascular medicine

Rath D, Schaeffeler E, Winter S, Levertov S, Müller K, Droppa M, Stimpfle F, Langer HF, Gawaz M, Schwab M, Geisler T.
PMID: 28871283
Front Cardiovasc Med. 2017 Aug 21;4:52. doi: 10.3389/fcvm.2017.00052. eCollection 2017.

BACKGROUND: Platelet membrane glycoprotein receptors mediate thrombus formation. GP Ia/IIa is an essential platelet integrin receptor. Single-nucleotide polymorphisms (SNPs) of the GP Ia/IIa gene alter GP Ia/IIa expression; however, their influence on cardiovascular disease remains unclear. This study aimed...

Dicarbonyl Stress and Glyoxalase-1 in Skeletal Muscle: Implications for Insulin Resistance and Type 2 Diabetes.

Frontiers in cardiovascular medicine

Mey JT, Haus JM.
PMID: 30250846
Front Cardiovasc Med. 2018 Sep 10;5:117. doi: 10.3389/fcvm.2018.00117. eCollection 2018.

Glyoxalase-1 (GLO1) is a ubiquitously expressed cytosolic protein which plays a role in the natural maintenance of cellular health and is abundantly expressed in human skeletal muscle. A consequence of reduced GLO1 protein expression is cellular dicarbonyl stress, which...

Automatic Estimation of Coronary Blood Flow Velocity Step 1 for Developing a Tool to Diagnose Patients With Micro-Vascular Angina Pectoris.

Frontiers in cardiovascular medicine

Khanmohammadi M, Engan K, Sæland C, Eftestøl T, Larsen AI.
PMID: 30740396
Front Cardiovasc Med. 2019 Jan 22;6:1. doi: 10.3389/fcvm.2019.00001. eCollection 2019.

No abstract available.

Higher Dispersion Measures of Conduction and Repolarization in Type 1 Compared to Non-type 1 Brugada Syndrome Patients: An Electrocardiographic Study From a Single Center.

Frontiers in cardiovascular medicine

Tse G, Li KHC, Li G, Liu T, Bazoukis G, Wong WT, Chan MTV, Wong MCS, Xia Y, Letsas KP, Chan GCP, Chan YS, Wu WKK.
PMID: 30338262
Front Cardiovasc Med. 2018 Oct 04;5:132. doi: 10.3389/fcvm.2018.00132. eCollection 2018.

No abstract available.

Relevance of Multi-Omics Studies in Cardiovascular Diseases.

Frontiers in cardiovascular medicine

Leon-Mimila P, Wang J, Huertas-Vazquez A.
PMID: 31380393
Front Cardiovasc Med. 2019 Jul 17;6:91. doi: 10.3389/fcvm.2019.00091. eCollection 2019.

Cardiovascular diseases are the leading cause of death around the world. Despite the larger number of genes and loci identified, the precise mechanisms by which these genes influence risk of cardiovascular disease is not well understood. Recent advances in...

Tailored Practical Management of Patients With Atrial Fibrillation: A Risk Factor-Based Approach.

Frontiers in cardiovascular medicine

Pastori D, Menichelli D, Gingis R, Pignatelli P, Violi F.
PMID: 30915342
Front Cardiovasc Med. 2019 Mar 12;6:17. doi: 10.3389/fcvm.2019.00017. eCollection 2019.

The management of antithrombotic therapy for thromboprophylaxis in patients with atrial fibrillation (AF) has been recently evolved by the progressive replacement of vitamin K antagonists with the non-vitamin K antagonist oral anticoagulants (NOACs). However, while these drugs are effective...

Neutrophils in Post-myocardial Infarction Inflammation: Damage vs. Resolution?.

Frontiers in cardiovascular medicine

Puhl SL, Steffens S.
PMID: 30937305
Front Cardiovasc Med. 2019 Mar 18;6:25. doi: 10.3389/fcvm.2019.00025. eCollection 2019.

Inflammation not only plays a crucial role in acute ischemic cardiac injury, but also contributes to post-infarction repair and remodeling. Traditionally, neutrophils have been merely considered as detrimental in the setting of an acute myocardial infarction. However, recently published...

RNAs and RNA-Binding Proteins in Immuno-Metabolic Homeostasis and Diseases.

Frontiers in cardiovascular medicine

Salem ESB, Vonberg AD, Borra VJ, Gill RK, Nakamura T.
PMID: 31482095
Front Cardiovasc Med. 2019 Aug 20;6:106. doi: 10.3389/fcvm.2019.00106. eCollection 2019.

The increasing prevalence of worldwide obesity has emerged as a major risk factor for type 2 diabetes (T2D), hepatosteatosis, and cardiovascular disease. Accumulating evidence indicates that obesity has strong inflammatory underpinnings tightly linked to the development of metabolic diseases....

Chinese Herbal Medicine as a Potential Treatment of Abdominal Aortic Aneurysm.

Frontiers in cardiovascular medicine

Seto SW, Chang D, Kiat H, Wang N, Bensoussan A.
PMID: 29732374
Front Cardiovasc Med. 2018 Apr 20;5:33. doi: 10.3389/fcvm.2018.00033. eCollection 2018.

Abdominal aortic aneurysm (AAA) is an irreversible condition where the abdominal aorta is dilated leading to potentially fatal consequence of aortic rupture. Multiple mechanisms are involved in the development and progression of AAA, including chronic inflammation, oxidative stress, vascular...

Cell Phenotype Transitions in Cardiovascular Calcification.

Frontiers in cardiovascular medicine

Hortells L, Sur S, St Hilaire C.
PMID: 29632866
Front Cardiovasc Med. 2018 Mar 26;5:27. doi: 10.3389/fcvm.2018.00027. eCollection 2018.

Cardiovascular calcification was originally considered a passive, degenerative process, however with the advance of cellular and molecular biology techniques it is now appreciated that ectopic calcification is an active biological process. Vascular calcification is the most common form of...

Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction.

Frontiers in cardiovascular medicine

Naesgaard PA, Grundt H, Nordøy AF, Staines H, Nilsen DWT.
PMID: 28791297
Front Cardiovasc Med. 2017 Jul 24;4:41. doi: 10.3389/fcvm.2017.00041. eCollection 2017.

BACKGROUND: Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce.OBJECTIVES: We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on...

Prolonged Postoperative Vasoplegia in Pediatric Patients on Chronic Angiotensin II Blocker Treatment.

Frontiers in cardiovascular medicine

Pandya NR, Alphonso N, Tu Q, Venugopal P, Schlapbach LJ.
PMID: 30234130
Front Cardiovasc Med. 2018 Sep 04;5:121. doi: 10.3389/fcvm.2018.00121. eCollection 2018.

Prolonged postoperative vasoplegia is known to occur following cardiac surgery in patients on chronic angiotensin II receptor blocker (ARB) treatment in adults. The perioperative management of these drugs in the pediatric population is not well described and here we...

Showing 25 to 36 of 3295 entries