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Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons.

Journal of pain research

Anand U, Oldfield C, Pacchetti B, Anand P, Sodergren MH.
PMID: 34853533
J Pain Res. 2021 Nov 24;14:3603-3614. doi: 10.2147/JPR.S336773. eCollection 2021.

BACKGROUND: The analgesic effects of MATERIALS AND METHODS: Adult rat DRG were dissected and enzyme digested to obtain a neuronal suspension in BSF2 medium containing 2% fetal calf serum, and the neurotrophic factors NGF and GDNF. After 48 h,...

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Anand U, Oldfield C, Pacchetti B, et al. Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons. J Pain Res. 2021;14:3603-3614doi: 10.2147/JPR.S336773.
Anand, U., Oldfield, C., Pacchetti, B., Anand, P., & Sodergren, M. H. (2021). Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons. Journal of pain research, 143603-3614. https://doi.org/10.2147/JPR.S336773
Anand, Uma, et al. "Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons." Journal of pain research vol. 14 (2021): 3603-3614. doi: https://doi.org/10.2147/JPR.S336773
Anand U, Oldfield C, Pacchetti B, Anand P, Sodergren MH. Dose-Related Inhibition of Capsaicin Responses by Cannabinoids CBG, CBD, THC and their Combination in Cultured Sensory Neurons. J Pain Res. 2021 Nov 24;14:3603-3614. doi: 10.2147/JPR.S336773. eCollection 2021. PMID: 34853533; PMCID: PMC8627890.
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An Evolutionary Orthogonal Component Analysis Method for Incremental Dimensionality Reduction.

IEEE transactions on neural networks and learning systems

Zhang T, Shen F, Zhu T, Zhao J.
PMID: 33112751
IEEE Trans Neural Netw Learn Syst. 2022 Jan;33(1):392-405. doi: 10.1109/TNNLS.2020.3027852. Epub 2022 Jan 05.

In order to quickly discover the low-dimensional representation of high-dimensional noisy data in online environments, we transform the linear dimensionality reduction problem into the problem of learning the bases of linear feature subspaces. Based on that, we propose a...

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Zhang T, Shen F, Zhu T, et al. An Evolutionary Orthogonal Component Analysis Method for Incremental Dimensionality Reduction. IEEE Trans Neural Netw Learn Syst. 2022;33(1):392-405doi: 10.1109/TNNLS.2020.3027852.
Zhang, T., Shen, F., Zhu, T., & Zhao, J. (2022). An Evolutionary Orthogonal Component Analysis Method for Incremental Dimensionality Reduction. IEEE transactions on neural networks and learning systems, 33(1), 392-405. https://doi.org/10.1109/TNNLS.2020.3027852
Zhang, Tianyue, et al. "An Evolutionary Orthogonal Component Analysis Method for Incremental Dimensionality Reduction." IEEE transactions on neural networks and learning systems vol. 33,1 (2022): 392-405. doi: https://doi.org/10.1109/TNNLS.2020.3027852
Zhang T, Shen F, Zhu T, Zhao J. An Evolutionary Orthogonal Component Analysis Method for Incremental Dimensionality Reduction. IEEE Trans Neural Netw Learn Syst. 2022 Jan;33(1):392-405. doi: 10.1109/TNNLS.2020.3027852. Epub 2022 Jan 05. PMID: 33112751.
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Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019.

Vaccine

Li AJ, Manzi F, Kyesi F, Makame Y, Mwengee W, Fleming M, Mkopi A, Mmbaga S, Lyimo D, Loharikar A.
PMID: 34229889
Vaccine. 2021 Jul 03; doi: 10.1016/j.vaccine.2021.06.047. Epub 2021 Jul 03.

BACKGROUND: In April 2018, Tanzania introduced the human papillomavirus (HPV) vaccine nationally to 14-year-old girls, utilizing routine delivery strategies (i.e. vaccinating girls at health facilities and community outreach, including schools). We sought to assess awareness, feasibility, and acceptability of...

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Li AJ, Manzi F, Kyesi F, et al. Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019. Vaccine. 2021;doi: 10.1016/j.vaccine.2021.06.047.
Li, A. J., Manzi, F., Kyesi, F., Makame, Y., Mwengee, W., Fleming, M., Mkopi, A., Mmbaga, S., Lyimo, D., & Loharikar, A. (2021). Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019. Vaccine, . https://doi.org/10.1016/j.vaccine.2021.06.047
Li, Anyie J, et al. "Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019." Vaccine vol. (2021). doi: https://doi.org/10.1016/j.vaccine.2021.06.047
Li AJ, Manzi F, Kyesi F, Makame Y, Mwengee W, Fleming M, Mkopi A, Mmbaga S, Lyimo D, Loharikar A. Tanzania's human papillomavirus (HPV) vaccination program: Community awareness, feasibility, and acceptability of a national HPV vaccination program, 2019. Vaccine. 2021 Jul 03; doi: 10.1016/j.vaccine.2021.06.047. Epub 2021 Jul 03. PMID: 34229889.
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Variability in interbeat duration influences myocardial contractility in rat cardiac trabeculae.

The open cardiovascular medicine journal

Torres CA, Varian KD, Janssen PM.
PMID: 19440237
Open Cardiovasc Med J. 2008;2:100-4. doi: 10.2174/1874192400802010100. Epub 2008 Nov 21.

There is an intense search for positive inotropic strategies. It is well known that the interbeat duration is a critical determinant of cardiac contractility. Generally, when frequency increases, so does contractile strength. We hypothesize that the beat-to-beat variability at...

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Torres CA, Varian KD, Janssen PM. Variability in interbeat duration influences myocardial contractility in rat cardiac trabeculae. Open Cardiovasc Med J. 2008;2:100-4doi: 10.2174/1874192400802010100.
Torres, C. A., Varian, K. D., & Janssen, P. M. (2008). Variability in interbeat duration influences myocardial contractility in rat cardiac trabeculae. The open cardiovascular medicine journal, 2100-4. https://doi.org/10.2174/1874192400802010100
Torres, Carlos A A, et al. "Variability in interbeat duration influences myocardial contractility in rat cardiac trabeculae." The open cardiovascular medicine journal vol. 2 (2008): 100-4. doi: https://doi.org/10.2174/1874192400802010100
Torres CA, Varian KD, Janssen PM. Variability in interbeat duration influences myocardial contractility in rat cardiac trabeculae. Open Cardiovasc Med J. 2008;2:100-4. doi: 10.2174/1874192400802010100. Epub 2008 Nov 21. PMID: 19440237; PMCID: PMC2627530.
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Antigenic Diversity in .

Frontiers in genetics

Allan FK, Jayaraman S, Paxton E, Sindoya E, Kibona T, Fyumagwa R, Mramba F, Torr SJ, Hemmink JD, Toye P, Lembo T, Handel I, Auty HK, Morrison WI, Morrison LJ.
PMID: 34335691
Front Genet. 2021 Jul 15;12:684127. doi: 10.3389/fgene.2021.684127. eCollection 2021.

East Coast fever (ECF) in cattle is caused by the Apicomplexan protozoan parasite

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Allan FK, Jayaraman S, Paxton E, et al. Antigenic Diversity in . Front Genet. 2021;12:684127doi: 10.3389/fgene.2021.684127.
Allan, F. K., Jayaraman, S., Paxton, E., Sindoya, E., Kibona, T., Fyumagwa, R., Mramba, F., Torr, S. J., Hemmink, J. D., Toye, P., Lembo, T., Handel, I., Auty, H. K., Morrison, W. I., & Morrison, L. J. (2021). Antigenic Diversity in . Frontiers in genetics, 12684127. https://doi.org/10.3389/fgene.2021.684127
Allan, Fiona K, et al. "Antigenic Diversity in ." Frontiers in genetics vol. 12 (2021): 684127. doi: https://doi.org/10.3389/fgene.2021.684127
Allan FK, Jayaraman S, Paxton E, Sindoya E, Kibona T, Fyumagwa R, Mramba F, Torr SJ, Hemmink JD, Toye P, Lembo T, Handel I, Auty HK, Morrison WI, Morrison LJ. Antigenic Diversity in . Front Genet. 2021 Jul 15;12:684127. doi: 10.3389/fgene.2021.684127. eCollection 2021. PMID: 34335691; PMCID: PMC8320539.
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Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone.

Cardiovascular research

Gierhardt M, Pak O, Sydykov A, Kraut S, Schäffer J, Garcia C, Veith C, Zeidan EM, Brosien M, Quanz K, Esfandiary A, Saraji A, Hadzic S, Kojonazarov B, Wilhelm J, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Herden C, Schulz R, Weissmann N, Heger J, Sommer N.
PMID: 33119054
Cardiovasc Res. 2022 Jan 07;118(1):305-315. doi: 10.1093/cvr/cvaa310.

AIMS: The pulmonary vascular tone and hypoxia-induced alterations of the pulmonary vasculature may be regulated by the mitochondrial membrane permeability transition pore (mPTP) that controls mitochondrial calcium load and apoptosis. We thus investigated, if the mitochondrial proteins p66shc and...

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Gierhardt M, Pak O, Sydykov A, et al. Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovasc Res. 2022;118(1):305-315doi: 10.1093/cvr/cvaa310.
Gierhardt, M., Pak, O., Sydykov, A., Kraut, S., Schäffer, J., Garcia, C., Veith, C., Zeidan, E. M., Brosien, M., Quanz, K., Esfandiary, A., Saraji, A., Hadzic, S., Kojonazarov, B., Wilhelm, J., Ghofrani, H. A., Schermuly, R. T., Seeger, W., Grimminger, F., Herden, C., Schulz, R., Weissmann, N., Heger, J., & Sommer, N. (2022). Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovascular research, 118(1), 305-315. https://doi.org/10.1093/cvr/cvaa310
Gierhardt, Mareike, et al. "Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone." Cardiovascular research vol. 118,1 (2022): 305-315. doi: https://doi.org/10.1093/cvr/cvaa310
Gierhardt M, Pak O, Sydykov A, Kraut S, Schäffer J, Garcia C, Veith C, Zeidan EM, Brosien M, Quanz K, Esfandiary A, Saraji A, Hadzic S, Kojonazarov B, Wilhelm J, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Herden C, Schulz R, Weissmann N, Heger J, Sommer N. Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone. Cardiovasc Res. 2022 Jan 07;118(1):305-315. doi: 10.1093/cvr/cvaa310. PMID: 33119054.
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A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca.

Bio-protocol

Trabalza S, Buonaurio R, Del Pino AM, Palmerini CA, van den Burg HA, Moretti C.
PMID: 33855111
Bio Protoc. 2021 Mar 20;11(6):e3949. doi: 10.21769/BioProtoc.3949. eCollection 2021 Mar 20.

Calcium signaling is an emerging mechanism by which bacteria respond to environmental cues. To measure the intracellular free-calcium concentration in bacterial cells, [Ca

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Trabalza S, Buonaurio R, Del Pino AM, et al. A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca. Bio Protoc. 2021;11(6):e3949doi: 10.21769/BioProtoc.3949.
Trabalza, S., Buonaurio, R., Del Pino, A. M., Palmerini, C. A., van den Burg, H. A., & Moretti, C. (2021). A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca. Bio-protocol, 11(6), e3949. https://doi.org/10.21769/BioProtoc.3949
Trabalza, Simone, et al. "A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca." Bio-protocol vol. 11,6 (2021): e3949. doi: https://doi.org/10.21769/BioProtoc.3949
Trabalza S, Buonaurio R, Del Pino AM, Palmerini CA, van den Burg HA, Moretti C. A Spectrofluorophotometrical Method Based on Fura-2-AM Probe to Determine Cytosolic Ca. Bio Protoc. 2021 Mar 20;11(6):e3949. doi: 10.21769/BioProtoc.3949. eCollection 2021 Mar 20. PMID: 33855111; PMCID: PMC8032496.
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Performance Assessment of the Universal Vital Assessment Score vs Other Illness Severity Scores for Predicting Risk of In-Hospital Death Among Adult Febrile Inpatients in Northern Tanzania, 2016-2019.

JAMA network open

Bonnewell JP, Rubach MP, Madut DB, Carugati M, Maze MJ, Kilonzo KG, Lyamuya F, Marandu A, Kalengo NH, Lwezaula BF, Mmbaga BT, Maro VP, Crump JA.
PMID: 34913982
JAMA Netw Open. 2021 Dec 01;4(12):e2136398. doi: 10.1001/jamanetworkopen.2021.36398.

IMPORTANCE: Severity scores are used to improve triage of hospitalized patients in high-income settings, but the scores may not translate well to low- and middle-income settings such as sub-Saharan Africa.OBJECTIVE: To assess the performance of the Universal Vital Assessment...

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Bonnewell JP, Rubach MP, Madut DB, et al. Performance Assessment of the Universal Vital Assessment Score vs Other Illness Severity Scores for Predicting Risk of In-Hospital Death Among Adult Febrile Inpatients in Northern Tanzania, 2016-2019. JAMA Netw Open. 2021;4(12):e2136398doi: 10.1001/jamanetworkopen.2021.36398.
Bonnewell, J. P., Rubach, M. P., Madut, D. B., Carugati, M., Maze, M. J., Kilonzo, K. G., Lyamuya, F., Marandu, A., Kalengo, N. H., Lwezaula, B. F., Mmbaga, B. T., Maro, V. P., & Crump, J. A. (2021). Performance Assessment of the Universal Vital Assessment Score vs Other Illness Severity Scores for Predicting Risk of In-Hospital Death Among Adult Febrile Inpatients in Northern Tanzania, 2016-2019. JAMA network open, 4(12), e2136398. https://doi.org/10.1001/jamanetworkopen.2021.36398
Bonnewell, John P, et al. "Performance Assessment of the Universal Vital Assessment Score vs Other Illness Severity Scores for Predicting Risk of In-Hospital Death Among Adult Febrile Inpatients in Northern Tanzania, 2016-2019." JAMA network open vol. 4,12 (2021): e2136398. doi: https://doi.org/10.1001/jamanetworkopen.2021.36398
Bonnewell JP, Rubach MP, Madut DB, Carugati M, Maze MJ, Kilonzo KG, Lyamuya F, Marandu A, Kalengo NH, Lwezaula BF, Mmbaga BT, Maro VP, Crump JA. Performance Assessment of the Universal Vital Assessment Score vs Other Illness Severity Scores for Predicting Risk of In-Hospital Death Among Adult Febrile Inpatients in Northern Tanzania, 2016-2019. JAMA Netw Open. 2021 Dec 01;4(12):e2136398. doi: 10.1001/jamanetworkopen.2021.36398. PMID: 34913982; PMCID: PMC8678687.
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Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review.

Case reports in obstetrics and gynecology

Mvunta DH, Amiji F, Suleiman M, Baraka F, Abdallah I, Kazabula M, Wangwe PJT, August F.
PMID: 33833884
Case Rep Obstet Gynecol. 2021 Mar 24;2021:6695117. doi: 10.1155/2021/6695117. eCollection 2021.

BACKGROUND: Pregnancy luteomas are rare, benign, ovarian neoplasms resulting from increased androgenic activity during pregnancy. Often, they occur asymptomatically and are only diagnosed incidentally during imaging or surgery: cesarean section or postpartum tubal ligation. Most common symptoms associated with...

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Mvunta DH, Amiji F, Suleiman M, et al. Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review. Case Rep Obstet Gynecol. 2021;2021:6695117doi: 10.1155/2021/6695117.
Mvunta, D. H., Amiji, F., Suleiman, M., Baraka, F., Abdallah, I., Kazabula, M., Wangwe, P. J. T., & August, F. (2021). Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review. Case reports in obstetrics and gynecology, 20216695117. https://doi.org/10.1155/2021/6695117
Mvunta, David Hamisi, et al. "Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review." Case reports in obstetrics and gynecology vol. 2021 (2021): 6695117. doi: https://doi.org/10.1155/2021/6695117
Mvunta DH, Amiji F, Suleiman M, Baraka F, Abdallah I, Kazabula M, Wangwe PJT, August F. Hirsutism Caused by Pregnancy Luteoma in a Low-Resource Setting: A Case Report and Literature Review. Case Rep Obstet Gynecol. 2021 Mar 24;2021:6695117. doi: 10.1155/2021/6695117. eCollection 2021. PMID: 33833884; PMCID: PMC8016591.
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Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia.

International journal of biological macromolecules

Dong Z, Dong G, Lai F, Wu H, Zhan Q.
PMID: 34478790
Int J Biol Macromol. 2021 Nov 01;190:101-112. doi: 10.1016/j.ijbiomac.2021.08.189. Epub 2021 Aug 31.

The development of selenized polysaccharides is a promising strategy for the dietary selenium supplementation. The purpose of this research is to determine the influence of selenium on the structure and bioactivity of a polysaccharide fraction (MPN) isolated from Ganoderma...

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Dong Z, Dong G, Lai F, et al. Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia. Int J Biol Macromol. 2021;190:101-112doi: 10.1016/j.ijbiomac.2021.08.189.
Dong, Z., Dong, G., Lai, F., Wu, H., & Zhan, Q. (2021). Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia. International journal of biological macromolecules, 190101-112. https://doi.org/10.1016/j.ijbiomac.2021.08.189
Dong, Zhou, et al. "Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia." International journal of biological macromolecules vol. 190 (2021): 101-112. doi: https://doi.org/10.1016/j.ijbiomac.2021.08.189
Dong Z, Dong G, Lai F, Wu H, Zhan Q. Purification and comparative study of bioactivities of a natural selenized polysaccharide from Ganoderma Lucidum mycelia. Int J Biol Macromol. 2021 Nov 01;190:101-112. doi: 10.1016/j.ijbiomac.2021.08.189. Epub 2021 Aug 31. PMID: 34478790.
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Loading acetoxymethyl ester fluorescent dyes into the cytoplasm of Arabidopsis and Commelina guard cells.

The New phytologist

Kuchitsu K, Ward JM, Allen GJ, Schelle I, Schroeder JI.
PMID: 33863225
New Phytol. 2002 Mar;153(3):527-533. doi: 10.1046/j.0028-646X.2001.00346.x. Epub 2002 Mar 05.

•  Cytosolic calcium and pH changes are integral components of guard cell signal transduction. Acetoxymethyl (AM) ester-linked Ca

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Kuchitsu K, Ward JM, Allen GJ, et al. Loading acetoxymethyl ester fluorescent dyes into the cytoplasm of Arabidopsis and Commelina guard cells. New Phytol. 2002;153(3):527-533doi: 10.1046/j.0028-646X.2001.00346.x.
Kuchitsu, K., Ward, J. M., Allen, G. J., Schelle, I., & Schroeder, J. I. (2002). Loading acetoxymethyl ester fluorescent dyes into the cytoplasm of Arabidopsis and Commelina guard cells. The New phytologist, 153(3), 527-533. https://doi.org/10.1046/j.0028-646X.2001.00346.x
Kuchitsu, Kazuyuki, et al. "Loading acetoxymethyl ester fluorescent dyes into the cytoplasm of Arabidopsis and Commelina guard cells." The New phytologist vol. 153,3 (2002): 527-533. doi: https://doi.org/10.1046/j.0028-646X.2001.00346.x
Kuchitsu K, Ward JM, Allen GJ, Schelle I, Schroeder JI. Loading acetoxymethyl ester fluorescent dyes into the cytoplasm of Arabidopsis and Commelina guard cells. New Phytol. 2002 Mar;153(3):527-533. doi: 10.1046/j.0028-646X.2001.00346.x. Epub 2002 Mar 05. PMID: 33863225.
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CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis.

European journal of clinical investigation

Yu J, Chen X, Li J, Wang F.
PMID: 33769559
Eur J Clin Invest. 2021 Jul;51(7):e13540. doi: 10.1111/eci.13540. Epub 2021 Mar 26.

BACKGROUND: Circular RNAs (circRNAs) have emerged as vital regulators in human cancers, including colorectal cancer (CRC). In this study, we aimed to explore the roles of circRUNX1 in CRC.METHODS: The levels of circRUNX1, RUNX1 mRNA, solute carrier family 38...

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Yu J, Chen X, Li J, et al. CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis. Eur J Clin Invest. 2021;51(7):e13540doi: 10.1111/eci.13540.
Yu, J., Chen, X., Li, J., & Wang, F. (2021). CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis. European journal of clinical investigation, 51(7), e13540. https://doi.org/10.1111/eci.13540
Yu, Juan, et al. "CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis." European journal of clinical investigation vol. 51,7 (2021): e13540. doi: https://doi.org/10.1111/eci.13540
Yu J, Chen X, Li J, Wang F. CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis. Eur J Clin Invest. 2021 Jul;51(7):e13540. doi: 10.1111/eci.13540. Epub 2021 Mar 26. PMID: 33769559.
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